Unexpected Compensatory Increase in Shank3 Transcripts in Shank3 Knock-Out Mice Having Partial Deletions of Exons

An autism-linked missense mutation in SHANK3 reveals the modularity of Shank3 function

(2019) Li Wang et al.   MOLECULAR PSYCHIATRY

Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice

(2019) Yinhua Zhang et al.   Frontiers in Molecular Neuroscience

Transcriptome analyses suggest minimal effects of Shank3 dosage on directional gene expression changes in the mouse striatum

(2019) Yeunkum Lee et al.   Animal Cells and Systems

USP8 Deubiquitinates SHANK3 to Control Synapse Density and SHANK3 Activity-dependent Protein Levels

(2018) Meghan Kerrisk Campbell et al.   JOURNAL OF NEUROSCIENCE

Social deficits in Shank3-deficient mouse models of autism are rescued by histone deacetylase (HDAC) inhibition

(2018) Luye Qin et al.   NATURE NEUROSCIENCE

Functional Relevance of Missense Mutations Affecting the N-Terminal Part of Shank3 Found in Autistic Patients

(2018) Fatemeh Hassani Nia et al.   Frontiers in Molecular Neuroscience

Integrative Brain Transcriptome Analysis Reveals Region-Specific and Broad Molecular Changes in Shank3-Overexpressing Mice

(2018) Chunmei Jin et al.   Frontiers in Molecular Neuroscience

Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2−/− Mice

(2018) Changuk Chung et al.   BIOLOGICAL PSYCHIATRY

Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background

(2018) Chunmei Jin et al.   Molecular Brain

Transcriptome analysis of Shank3-overexpressing mice reveals unique molecular changes in the hypothalamus

(2018) Chunmei Jin et al.   Molecular Brain

SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras

(2017) Johanna Lilja et al.   NATURE CELL BIOLOGY

SHANK proteins: roles at the synapse and in autism spectrum disorder

(2017) Patricia Monteiro et al.   NATURE REVIEWS NEUROSCIENCE

Age-dependent decrease of GAD65/67 mRNAs but normal densities of GABAergic interneurons in the brain regions of Shank3 -overexpressing manic mouse model

(2017) Bokyoung Lee et al.   NEUROSCIENCE LETTERS

Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling

(2017) Yeunkum Lee et al.   Frontiers in Molecular Neuroscience

Integrative Analysis of Brain Region-specific Shank3 Interactomes for Understanding the Heterogeneity of Neuronal Pathophysiology Related to SHANK3 Mutations

(2017) Yeunkum Lee et al.   Frontiers in Molecular Neuroscience

Bipolar Disorder Associated microRNA, miR-1908-5p, Regulates the Expression of Genes Functioning in Neuronal Glutamatergic Synapses

(2016) Yoonhee Kim et al.   Experimental Neurobiology

Shank3-mutant mice lacking exon 9 show altered excitation/inhibition balance, enhanced rearing, and spatial memory deficit

(2015) Jiseok Lee et al.   Frontiers in Cellular Neuroscience

Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders

(2015) Su-Yeon Choi et al.   Molecular Brain

Phenotypic and functional analysis of SHANK3 stop mutations identified in individuals with ASD and/or ID

(2015) Daniela M Cochoy et al.   Molecular Autism

Fragile X-like behaviors and abnormal cortical dendritic spines in Cytoplasmic FMR1-interacting protein 2-mutant mice

(2014) Kihoon Han et al.   HUMAN MOLECULAR GENETICS

Transcriptional and functional complexity of Shank3 provides a molecular framework to understand the phenotypic heterogeneity of SHANK3 causing autism and Shank3 mutant mice

(2014) Xiaoming Wang et al.   Molecular Autism

Human-specific regulation of MeCP2 levels in fetal brains by microRNA miR-483-5p

(2013) K. Han et al.   GENES & DEVELOPMENT

Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders

(2013) Li Zhu et al.   HUMAN MOLECULAR GENETICS

Loss of Predominant Shank3 Isoforms Results in Hippocampus-Dependent Impairments in Behavior and Synaptic Transmission

(2013) M. Kouser et al.   JOURNAL OF NEUROSCIENCE

SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties

(2013) Kihoon Han et al.   NATURE

Modeling Autism by SHANK Gene Mutations in Mice

(2013) Yong-hui Jiang et al.   NEURON

Synaptic dysfunction and abnormal behaviors in mice lacking major isoforms of Shank3

(2011) Xiaoming Wang et al.   HUMAN MOLECULAR GENETICS

Shank3 mutant mice display autistic-like behaviours and striatal dysfunction

(2011) João Peça et al.   NATURE

Postsynaptic ProSAP/Shank scaffolds in the cross-hair of synaptopathies

(2011) Andreas M. Grabrucker et al.   TRENDS IN CELL BIOLOGY

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

(2011) Ozlem Bozdagi et al.   Molecular Autism

The Postsynaptic Density Proteins Homer and Shank Form a Polymeric Network Structure

(2009) Mariko Kato Hayashi et al.   CELL

Regulated RalBP1 Binding to RalA and PSD-95 Controls AMPA Receptor Endocytosis and LTD

(2009) Kihoon Han et al.   PLOS BIOLOGY