Involvement of NLRP3 and NLRC4 Inflammasome in Uropathogenic E. coli Mediated Urinary Tract Infections

The genetic polymorphism and expression profiles of NLRP3 inflammasome in patients with chronic myeloid leukemia

(2018) Amin Zhang et al.   HUMAN IMMUNOLOGY

NLRP3 expression and urinary HSP72 in relation to biomarkers of inflammation and oxidative stress in diabetic nephropathy patients

(2017) Hemat El-Sayed El-Horany et al.   IUBMB LIFE

Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation

(2016) Anna Waldhuber et al.   JOURNAL OF CLINICAL INVESTIGATION

Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice

(2016) Yue Zhao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The choice of phorbol 12-myristate 13-acetate differentiation protocol influences the response of THP-1 macrophages to a pro-inflammatory stimulus

(2016) Maria E. Lund et al.   JOURNAL OF IMMUNOLOGICAL METHODS

The NLRP3 Inflammasome Mediates Inflammation Produced by Bladder Outlet Obstruction

(2016) Francis M. Hughes et al.   JOURNAL OF UROLOGY

NLRP3 Inflammasome Expression and Activation in Human Atherosclerosis

(2016) Geena Paramel Varghese et al.   Journal of the American Heart Association

Inflammasomes and Their Role in Innate Immunity of Sexually Transmitted Infections

(2016) Vivek Verma et al.   Frontiers in Immunology

Molecular mechanisms regulating NLRP3 inflammasome activation

(2015) Eun-Kyeong Jo et al.   Cellular & Molecular Immunology

The NAIP-NLRC4 inflammasome in innate immune detection of bacterial flagellin and type III secretion apparatus

(2015) Yue Zhao et al.   IMMUNOLOGICAL REVIEWS

Increased expression of the NLRP3 inflammasome components in patients with Behçet’s disease

(2015) En Hyung Kim et al.   Journal of Inflammation-London

The Expression and Significance of NLRP3 Inflammasome in Patients with Primary Glomerular Diseases

(2015) Jing Xiong et al.   KIDNEY & BLOOD PRESSURE RESEARCH

Strain- and host species-specific inflammasome activation, IL-1β release and cell death in macrophages infected with uropathogenic Escherichia coli

(2015) K Schaale et al.   Mucosal Immunology

ATG16L1 deficiency in macrophages drives clearance of uropathogenic E. coli in an IL-1β-dependent manner

(2015) J W Symington et al.   Mucosal Immunology

Upregulation of NLRP3 Inflammasome in the Tears and Ocular Surface of Dry Eye Patients

(2015) Liangliang Niu et al.   PLoS One

Dysregulation ofEscherichia coliα-hemolysin expression alters the course of acute and persistent urinary tract infection

(2015) Kanna Nagamatsu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhanced activity of NLRP3 inflammasome in peripheral blood cells of patients with active rheumatoid arthritis

(2015) Christianna Choulaki et al.   ARTHRITIS RESEARCH & THERAPY

Epithelium-Intrinsic NAIP/NLRC4 Inflammasome Drives Infected Enterocyte Expulsion to Restrict Salmonella Replication in the Intestinal Mucosa

(2014) Mikael E. Sellin et al.   Cell Host & Microbe

CCR2 Mediates Homeostatic and Inflammatory Release of Gr1high Monocytes from the Bone Marrow, but Is Dispensable for Bladder Infiltration in Bacterial Urinary Tract Infection

(2014) D. R. Engel et al.   JOURNAL OF IMMUNOLOGY

Molecular Basis for Specific Recognition of Bacterial Ligands by NAIP/NLRC4 Inflammasomes

(2014) Jeannette L. Tenthorey et al.   MOLECULAR CELL

Mechanisms and biological functions of autophagy in diseased and ageing kidneys

(2014) Sophie Fougeray et al.   Nature Reviews Nephrology

Association of Angiotensin II Type 1 Receptor (A1166C) Gene Polymorphism and Its Increased Expression in Essential Hypertension: A Case-Control Study

(2014) Sudhir Chandra et al.   PLoS One

Actin polymerization as a key innate immune effector mechanism to controlSalmonellainfection

(2014) Si Ming Man et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder

(2013) Elísabet Alcocer-Gómez et al.   BRAIN BEHAVIOR AND IMMUNITY

NLRP3 inflammasome activation in coronary artery disease: results from prospective and randomized study of treatment with atorvastatin or rosuvastatin

(2013) Mamoru Satoh et al.   CLINICAL SCIENCE

Uropathogenic Escherichia coli virulence and innate immune responses during urinary tract infection

(2013) Glen C Ulett et al.   CURRENT OPINION IN MICROBIOLOGY

Human Bladder Uroepithelial Cells Synergize with Monocytes to Promote IL-10 Synthesis and Other Cytokine Responses to Uropathogenic Escherichia coli

(2013) Benjamin L. Duell et al.   PLoS One

Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation

(2013) J. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential effects of LPS fromEscherichia coliandPorphyromonas gingivalison IL-6 production in human periodontal ligament cells

(2012) Daniel Nebel et al.   ACTA ODONTOLOGICA SCANDINAVICA

Antioxidative properties of paraoxonase 2 in intestinal epithelial cells

(2012) Louis-Philippe Précourt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Expression and Cellular Localization of Inducible Nitric Oxide Synthase in Lipopolysaccharide-treated Rat Kidneys

(2012) Jae-Youn Choi et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Expression analysis of inflammasomes in experimental models of inflammatory and fibrotic liver disease

(2012) Sorina Georgiana Boaru et al.   Journal of Inflammation-London

Rapid induction of inflammatory lipid mediators by the inflammasome in vivo

(2012) Jakob von Moltke et al.   NATURE

BarA-UvrY Two-Component System Regulates Virulence of Uropathogenic E. coli CFT073

(2012) Senthilkumar Palaniyandi et al.   PLoS One

The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus

(2011) Yue Zhao et al.   NATURE

Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity

(2011) Eric M. Kofoed et al.   NATURE

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Targeting IL-1β in disease; the expanding role of NLRP3 inflammasome

(2010) Ioannis Mitroulis et al.   European Journal of Internal Medicine

The regulatory role of nitric oxide in proinflammatory cytokine expression during the induction and resolution of inflammation

(2010) Yoshiro Kobayashi   JOURNAL OF LEUKOCYTE BIOLOGY

Inhibition of TIR Domain Signaling by TcpC: MyD88-Dependent and Independent Effects on Escherichia coli Virulence

(2010) Manisha Yadav et al.   PLoS Pathogens

The Inflammasomes: Guardians of the Body

(2009) Fabio Martinon et al.   Annual Review of Immunology

Hemolysin of Uropathogenic Escherichia coli Evokes Extensive Shedding of the Uroepithelium and Hemorrhage in Bladder Tissue within the First 24 Hours after Intraurethral Inoculation of Mice

(2008) Y. C. Smith et al.   INFECTION AND IMMUNITY

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE

Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin

(2008) Karla L Lightfield et al.   NATURE IMMUNOLOGY

Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

(2008) Veit Hornung et al.   NATURE IMMUNOLOGY

Subversion of Toll-like receptor signaling by a unique family of bacterial Toll/interleukin-1 receptor domain–containing proteins

(2008) Christine Cirl et al.   NATURE MEDICINE

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE