Regulator of G protein signaling 12 enhances osteoclastogenesis by suppressing Nrf2-dependent antioxidant proteins to promote the generation of reactive oxygen species

Regulator of G protein signaling-12 modulates the dopamine transporter in ventral striatum and locomotor responses to psychostimulants

(2018) Joshua D Gross et al.   JOURNAL OF PSYCHOPHARMACOLOGY

IonStar enables high-precision, low-missing-data proteomics quantification in large biological cohorts

(2018) Xiaomeng Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulator of G protein signaling protein 12 (Rgs12) controls mouse osteoblast differentiation via calcium channel/oscillation and Gαi-ERK signaling

(2018) Ziqing Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

An IonStar Experimental Strategy for MS1 Ion Current-Based Quantification Using Ultrahigh-Field Orbitrap: Reproducible, In-Depth, and Accurate Protein Measurement in Large Cohorts

(2017) Xiaomeng Shen et al.   JOURNAL OF PROTEOME RESEARCH

Transcription factor proteomics-Tools, applications, and challenges

(2017) Jovan Simicevic et al.   PROTEOMICS

Advanced glycation end products biphasically modulate bone resorption in osteoclast-like cells

(2016) Ziqing Li et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Pivotal Role of Regulator of G-protein Signaling 12 in Pathological Cardiac HypertrophyNovelty and Significance

(2016) Jia Huang et al.   HYPERTENSION

Energy metabolism in osteoclast formation and activity

(2016) Silvia Lemma et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Heparan Sulfate Regulates the Structure and Function of Osteoprotegerin in Osteoclastogenesis

(2016) Miaomiao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomic approaches to study osteoclast biology

(2016) Sandra Segeletz et al.   PROTEOMICS

Ciliary IFT80 balances canonical versus non-canonical hedgehog signalling for osteoblast differentiation

(2016) Xue Yuan et al.   Nature Communications

Regulators of G protein signaling 12 promotes osteoclastogenesis in bone remodeling and pathological bone loss

(2015) X Yuan et al.   CELL DEATH AND DIFFERENTIATION

Reactive oxygen species and oxidative stress in osteoclastogenesis, skeletal aging and bone diseases

(2015) Danielle A. Callaway et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Role of regulator of G protein signaling proteins in bone

(2014) David Keinan   Frontiers in Bioscience-Landmark

Comparative analysis of the efficiency and specificity of myeloid-Cre deleting strains using ROSA-EYFP reporter mice

(2014) Clare L. Abram et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Characterization of Functional Reprogramming during Osteoclast Development Using Quantitative Proteomics and mRNA Profiling

(2014) Eunkyung An et al.   MOLECULAR & CELLULAR PROTEOMICS

Integrating Phosphoproteome and Transcriptome Reveals New Determinants of Macrophage Multinucleation

(2014) Maxime Rotival et al.   MOLECULAR & CELLULAR PROTEOMICS

FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation

(2014) Shoshana M. Bartell et al.   Nature Communications

Nrf2 deficiency induces oxidative stress and promotes RANKL-induced osteoclast differentiation

(2013) Seungha Hyeon et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mx1-Cre mediatedRgs12conditional knockout mice exhibit increased bone mass phenotype

(2013) Shuying Yang et al.   GENESIS

The Keap1/Nrf2 Protein Axis Plays a Role in Osteoclast Differentiation by Regulating Intracellular Reactive Oxygen Species Signaling

(2013) Hiroyuki Kanzaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Trends in Fracture Incidence: A Population-Based Study Over 20 Years

(2013) Shreyasee Amin et al.   JOURNAL OF BONE AND MINERAL RESEARCH

The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer

(2013) Emilia Kansanen et al.   Redox Biology

Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction

(2012) Jian Ye et al.   BMC BIOINFORMATICS

Proteomic analysis of podosome fractions from macrophages reveals similarities to spreading initiation centres

(2012) Pasquale Cervero et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Inhibitory effects of tert-butylhydroquinone on osteoclast differentiation via up-regulation of heme oxygenase-1 and down-regulation of HMGB1 release and NFATc1 expression

(2012) Yu Yamaguchi et al.   JOURNAL OF APPLIED TOXICOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The quantitative proteome of a human cell line

(2011) M. Beck et al.   Molecular Systems Biology

Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole

(2011) Yumi Abiko et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

RANKL-mediated Reactive Oxygen Species Pathway That Induces Long Lasting Ca2+Oscillations Essential for Osteoclastogenesis

(2010) Min Seuk Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Nrf2-Antioxidant Response Element Signaling Pathway and Its Activation by Oxidative Stress

(2009) Truyen Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of PGC-1β and iron uptake in mitochondrial biogenesis and osteoclast activation

(2009) Kiyo-aki Ishii et al.   NATURE MEDICINE

Regulation of Reactive Oxygen Species and Genomic Stability in Hematopoietic Stem Cells

(2008) Kazuhito Naka et al.   ANTIOXIDANTS & REDOX SIGNALING