Interferon lambda 4 impacts the genetic diversity of hepatitis C virus

IFITM s mediate viral evasion in acute and chronic hepatitis C virus infection

(2019) Florian Wrensch et al.   HEPATOLOGY

Interpreting Viral Deep Sequencing Data with GLUE

(2019) Joshua Singer et al.   Viruses-Basel

Correcting for Population Stratification Reduces False Positive and False Negative Results in Joint Analyses of Host and Pathogen Genomes

(2018) Olivier Naret et al.   Frontiers in Genetics

A polymorphic residue that attenuates the antiviral potential of interferon lambda 4 in hominid lineages

(2018) Connor G. G. Bamford et al.   PLoS Pathogens

IFN-λ3, not IFN-λ4, likely mediates IFNL3–IFNL4 haplotype–dependent hepatic inflammation and fibrosis

(2017) Mohammed Eslam et al.   NATURE GENETICS

Genome-to-genome analysis highlights the effect of the human innate and adaptive immune systems on the hepatitis C virus

(2017) M Azim Ansari et al.   NATURE GENETICS

The Role of Type III Interferons in Hepatitis C Virus Infection and Therapy

(2017) Janina Bruening et al.   Journal of Immunology Research

HLA-B*57 and IFNL4-related polymorphisms are associated with protection against HIV-1 disease progression in controllers

(2016) B Dominguez-Molina et al.   CLINICAL INFECTIOUS DISEASES

Bayesian Inference of the Evolution of a Phenotype Distribution on a Phylogenetic Tree

(2016) M. Azim Ansari et al.   GENETICS

Impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis

(2016) Graham R. Foster et al.   JOURNAL OF HEPATOLOGY

Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design

(2016) Brian G. Pierce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bayesian Inference of the Evolution of a Phenotype Distribution on a Phylogenetic Tree

(2016) M. Azim Ansari et al.   GENETICS

Association of Single-Nucleotide Polymorphisms inIL28B,but NotTNF-α,With Severity of Disease Caused by Andes Virus

(2015) Jenniffer Angulo et al.   CLINICAL INFECTIOUS DISEASES

Efficacy of Sofosbuvir Plus Ribavirin With or Without Peginterferon-Alfa in Patients With Hepatitis C Virus Genotype 3 Infection and Treatment-Experienced Patients With Cirrhosis and Hepatitis C Virus Genotype 2 Infection

(2015) Graham R. Foster et al.   GASTROENTEROLOGY

The broad assessment of HCV genotypes 1 and 3 antigenic targets reveals limited cross-reactivity with implications for vaccine design

(2015) Annette von Delft et al.   GUT

IFN-  is able to augment TLR-mediated activation and subsequent function of primary human B cells

(2015) R. A. de Groen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Viral genotype correlates with distinct liver gene transcription signatures in chronic hepatitis C virus infection

(2015) Mark W. Robinson et al.   LIVER INTERNATIONAL

A global reference for human genetic variation

(2015) Richard A. Gibbs et al.   NATURE

Longitudinal Sequence and Functional Evolution within Glycoprotein E2 in Hepatitis C Virus Genotype 3a Infection

(2015) Yousef M. O. Alhammad et al.   PLoS One

The past, present and future of neutralizing antibodies for hepatitis C virus

(2014) Jonathan K. Ball et al.   ANTIVIRAL RESEARCH

RAxML version 8: a tool for phylogenetic analysis and post-analysis of large phylogenies

(2014) Alexandros Stamatakis   BIOINFORMATICS

Association of serum IFN-λ3 with inflammatory and fibrosis markers in patients with chronic hepatitis C virus infection

(2014) Yoshihiko Aoki et al.   JOURNAL OF GASTROENTEROLOGY

Immunomodulatory Function of Interleukin 28B During Primary Infection With Cytomegalovirus

(2014) Adrian Egli et al.   JOURNAL OF INFECTIOUS DISEASES

Fast Principal Component Analysis of Large-Scale Genome-Wide Data

(2014) Gad Abraham et al.   PLoS One

Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes

(2014) Ewa Terczyńska-Dyla et al.   Nature Communications

IL-28B is a Key Regulator of B- and T-Cell Vaccine Responses against Influenza

(2014) Adrian Egli et al.   PLoS Pathogens

Modelling mutational and selection pressures on dinucleotides in eukaryotic phyla –selection against CpG and UpA in cytoplasmically expressed RNA and in RNA viruses

(2013) Peter Simmonds et al.   BMC GENOMICS

Association of IL28B genotype with fibrosis progression and clinical outcomes in patients with chronic hepatitis C: A longitudinal analysis

(2013) Mazen Noureddin et al.   HEPATOLOGY

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus

(2013) Ludmila Prokunina-Olsson et al.   NATURE GENETICS

Hepatitis C Virus E2 Envelope Glycoprotein Core Structure

(2013) L. Kong et al.   SCIENCE

Imputation-Based Meta-Analysis of Severe Malaria in Three African Populations

(2013) Gavin Band et al.   PLoS Genetics

Genome-Wide Association Study Identifies Variants Associated With Progression of Liver Fibrosis From HCV Infection

(2012) Etienne Patin et al.   GASTROENTEROLOGY

New advances in the molecular biology of hepatitis C virus infection: towards the identification of new treatment targets

(2012) Alexander Ploss et al.   GUT

Characterization of Hepatitis C Virus Particle Subpopulations Reveals Multiple Usage of the Scavenger Receptor BI for Entry Steps

(2012) Viet Loan Dao Thi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Improved whole-chromosome phasing for disease and population genetic studies

(2012) Olivier Delaneau et al.   NATURE METHODS

Structural basis of hepatitis C virus neutralization by broadly neutralizing antibody HCV1

(2012) L. Kong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluation of interleukin 28B single nucleotide polymorphisms in infants suffering from bronchiolitis

(2012) Carolina Scagnolari et al.   VIRUS RESEARCH

Scavenger receptor class B type I and the hypervariable region-1 of hepatitis C virus in cell entry and neutralisation

(2011) Viet Loan Dao Thi et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Genetic Variation in IL28B Is Associated With Chronic Hepatitis C and Treatment Failure: A Genome-Wide Association Study

(2010) Andri Rauch et al.   GASTROENTEROLOGY

The variable regions of hepatitis C virus glycoprotein E2 have an essential structural role in glycoprotein assembly and virion infectivity

(2010) K. McCaffrey et al.   JOURNAL OF GENERAL VIROLOGY

Identification of New Functional Regions in Hepatitis C Virus Envelope Glycoprotein E2

(2010) A. Albecka et al.   JOURNAL OF VIROLOGY

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

(2009) David L. Thomas et al.   NATURE

IL28B is associated with response to chronic hepatitis C interferon-α and ribavirin therapy

(2009) Vijayaprakash Suppiah et al.   NATURE GENETICS

Genome-wide association of IL28B with response to pegylated interferon-α and ribavirin therapy for chronic hepatitis C

(2009) Yasuhito Tanaka et al.   NATURE GENETICS

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics