Astroglial dysfunctions drive aberrant synaptogenesis and social behavioral deficits in mice with neonatal exposure to lengthy general anesthesia

Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial

(2019) Mary Ellen McCann et al.   LANCET

Sevoflurane induces cognitive impairment in young mice via autophagy

(2019) Xiaoning Wang et al.   PLoS One

Neuropsychological and Behavioral Outcomes after Exposure of Young Children to Procedures Requiring General Anesthesia

(2018) David O. Warner et al.   ANESTHESIOLOGY

Astrocytes, neurons, synapses: a tripartite view on cortical circuit development

(2018) Isabella Farhy-Tselnicker et al.   Neural Development

An Optical Neuron-Astrocyte Proximity Assay at Synaptic Distance Scales

(2018) J. Christopher Octeau et al.   NEURON

The influence of propofol anesthesia exposure on nonaversive memory retrieval and expression of molecules involved in memory process in the dorsal hippocampus in peripubertal rats

(2018) Željko Pavković et al.   PEDIATRIC ANESTHESIA

Disrupted Neuroglial Metabolic Coupling after Peripheral Surgery

(2017) Teresa Femenía et al.   JOURNAL OF NEUROSCIENCE

Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis

(2017) Jeff A. Stogsdill et al.   NATURE

Cell Biology of Astrocyte-Synapse Interactions

(2017) Nicola J. Allen et al.   NEURON

Early postnatal exposure to isoflurane causes cognitive deficits and disrupts development of newborn hippocampal neurons via activation of the mTOR pathway

(2017) Eunchai Kang et al.   PLOS BIOLOGY

Automated Functional Analysis of Astrocytes from Chronic Time-Lapse Calcium Imaging Data

(2017) Yinxue Wang et al.   Frontiers in Neuroinformatics

Sevoflurane Inhibits Glutamate-Aspartate Transporter and Glial Fibrillary Acidic Protein Expression in Hippocampal Astrocytes of Neonatal Rats Through the Janus Kinase/Signal Transducer and Activator of Transcription (JAK/STAT) Pathway

(2016) Wei Wang et al.   ANESTHESIA AND ANALGESIA

Learning, memory and synaptic plasticity in hippocampus in rats exposed to sevoflurane

(2016) Hongyan Xiao et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood

(2016) Lena S. Sun et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Propofol exposure during late stages of pregnancy impairs learning and memory in rat offspringviathe BDNF-TrkB signalling pathway

(2016) Liang Zhong et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Dysfunctional Calcium and Glutamate Signaling in Striatal Astrocytes from Huntington's Disease Model Mice

(2016) R. Jiang et al.   JOURNAL OF NEUROSCIENCE

Neurodevelopmental outcome at 2 years of age after general anaesthesia and awake-regional anaesthesia in infancy (GAS): an international multicentre, randomised controlled trial

(2016) Andrew J Davidson et al.   LANCET

Lasting impact of general anaesthesia on the brain: mechanisms and relevance

(2016) Laszlo Vutskits et al.   NATURE REVIEWS NEUROSCIENCE

Probing the Complexities of Astrocyte Calcium Signaling

(2016) Eiji Shigetomi et al.   TRENDS IN CELL BIOLOGY

Long-term Effects of Single or Multiple Neonatal Sevoflurane Exposures on Rat Hippocampal Ultrastructure

(2015) Levana G. Amrock et al.   ANESTHESIOLOGY

Ca2+ signaling in astrocytes from Ip3r2 −/− mice in brain slices and during startle responses in vivo

(2015) Rahul Srinivasan et al.   NATURE NEUROSCIENCE

Time-Resolved Imaging Reveals Heterogeneous Landscapes of Nanomolar Ca2+ in Neurons and Astroglia

(2015) Kaiyu Zheng et al.   NEURON

Do stars govern our actions? Astrocyte involvement in rodent behavior

(2015) João Filipe Oliveira et al.   TRENDS IN NEUROSCIENCES

Astrocytes Control Synapse Formation, Function, and Elimination

(2015) Won-Suk Chung et al.   Cold Spring Harbor Perspectives in Biology

Activity-Dependent Structural Plasticity of Perisynaptic Astrocytic Domains Promotes Excitatory Synapse Stability

(2014) Yann Bernardinelli et al.   CURRENT BIOLOGY

Isoflurane Impairs the Capacity of Astrocytes to Support Neuronal Development in a Mouse Dissociated Coculture Model

(2014) Yun Kyoung Ryu et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

(2014) Xiaoping Tong et al.   NATURE NEUROSCIENCE

Isoflurane exposure in newborn rats induces long-term cognitive dysfunction in males but not females

(2014) Bradley H. Lee et al.   NEUROPHARMACOLOGY

Glia selectively approach synapses on thin dendritic spines

(2014) N. Medvedev et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Early Exposure to Volatile Anesthetics Impairs Long-Term Associative Learning and Recognition Memory

(2014) Bradley H. Lee et al.   PLoS One

AMPA-silent synapses in brain development and pathology

(2013) Eric Hanse et al.   NATURE REVIEWS NEUROSCIENCE

Transformation of odor selectivity from projection neurons to single mushroom body neurons mapped with dual-color calcium imaging

(2013) H. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Duration of exposure to cranial vault surgery: associations with neurodevelopment among children with single-suture craniosynostosis

(2012) Heather L. Naumann et al.   PEDIATRIC ANESTHESIA

General anesthesia selectively disrupts astrocyte calcium signaling in the awake mouse cortex

(2012) A. S. Thrane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sevoflurane exposure in 7-day-old rats affects neurogenesis, neurodegeneration and neurocognitive function

(2012) Fang Fang et al.   Neuroscience Bulletin

Comparison of the Neuroapoptotic Properties of Equipotent Anesthetic Concentrations of Desflurane, Isoflurane, or Sevoflurane in Neonatal Mice

(2011) George K. Istaphanous et al.   ANESTHESIOLOGY

Developmental Stage-dependent Persistent Impact of Propofol Anesthesia on Dendritic Spines in the Rat Medial Prefrontal Cortex

(2011) Adrian Briner et al.   ANESTHESIOLOGY

Structural plasticity of perisynaptic astrocyte processes involves ezrin and metabotropic glutamate receptors

(2011) M. Lavialle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isoflurane-induced Neuroapoptosis in the Neonatal Rhesus Macaque Brain

(2010) Ansgar M. Brambrink et al.   ANESTHESIOLOGY

Behavioural phenotyping assays for mouse models of autism

(2010) Jill L. Silverman et al.   NATURE REVIEWS NEUROSCIENCE

Alterations of cortical pyramidal neurons in mice lacking high-affinity nicotinic receptors

(2010) I. Ballesteros-Yanez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neonatal Exposure to Sevoflurane Induces Abnormal Social Behaviors and Deficits in Fear Conditioning in Mice

(2009) Maiko Satomoto et al.   ANESTHESIOLOGY