Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects
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Title
Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects
Authors
Keywords
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Journal
Frontiers in Aging Neuroscience
Volume 11, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-08-07
DOI
10.3389/fnagi.2019.00204
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Note: Only part of the references are listed.- Why Microtubules Should Be Considered as One of the Supplementary Targets for Designing Neurotherapeutics
- (2019) Gaurav Das et al. ACS Chemical Neuroscience
- Tau regulates the microtubule-dependent migration of glioblastoma cells via the Rho-ROCK signaling pathway
- (2019) Gilles Breuzard et al. JOURNAL OF CELL SCIENCE
- Microtubules Deform the Nuclear Membrane and Disrupt Nucleocytoplasmic Transport in Tau-Mediated Frontotemporal Dementia
- (2019) Francesco Paonessa et al. Cell Reports
- The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?
- (2019) Yann Fichou et al. Acta Neuropathologica Communications
- A walk through tau therapeutic strategies
- (2019) Santosh Jadhav et al. Acta Neuropathologica Communications
- Tau: It’s Not What You Think
- (2019) Peter W. Baas et al. TRENDS IN CELL BIOLOGY
- An acetylation mimicking mutation, K274Q, in tau imparts neurotoxicity by enhancing tau aggregation and inhibiting tubulin polymerization
- (2019) Jitendra S. Rane et al. BIOCHEMICAL JOURNAL
- The Binding Mode of a Tau Peptide with Tubulin
- (2018) Harindranath Kadavath et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Tau Does Not Stabilize Axonal Microtubules but Rather Enables Them to Have Long Labile Domains
- (2018) Liang Qiang et al. CURRENT BIOLOGY
- Tau protein liquid–liquid phase separation can initiate tau aggregation
- (2018) Susanne Wegmann et al. EMBO JOURNAL
- SIRT1 Deacetylates Tau and Reduces Pathogenic Tau Spread in a Mouse Model of Tauopathy
- (2018) Sang-Won Min et al. JOURNAL OF NEUROSCIENCE
- Cytotoxicity of Tanshinone IIA combined with Taxol on drug-resist breast cancer cells MCF-7 through inhibition of Tau
- (2018) Hui Lin et al. PHYTOTHERAPY RESEARCH
- Near-atomic model of microtubule-tau interactions
- (2018) Elizabeth H. Kellogg et al. SCIENCE
- Tau Protein Disrupts Nucleocytoplasmic Transport in Alzheimer’s Disease
- (2018) Bahareh Eftekharzadeh et al. NEURON
- Two Tau binding sites on tubulin revealed by thiol-disulfide exchanges
- (2018) Marlène Martinho et al. Scientific Reports
- FTDP-17 Mutations Alter the Aggregation and Microtubule Stabilization Propensity of Tau in an Isoform-Specific Fashion
- (2018) Yamini Mutreja et al. BIOCHEMISTRY
- Loss of tubulin deglutamylase CCP1 causes infantile‐onset neurodegeneration
- (2018) Vandana Shashi et al. EMBO JOURNAL
- Excessive tubulin polyglutamylation causes neurodegeneration and perturbs neuronal transport
- (2018) Maria M Magiera et al. EMBO JOURNAL
- Zinc Induces Temperature-Dependent Reversible Self-Assembly of Tau
- (2018) Andrei Yu. Roman et al. JOURNAL OF MOLECULAR BIOLOGY
- An acetylation–phosphorylation switch that regulates tau aggregation propensity and function
- (2017) Yari Carlomagno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The tubulin code at a glance
- (2017) Sudarshan Gadadhar et al. JOURNAL OF CELL SCIENCE
- Interactions between Tau and Different Conformations of Tubulin: Implications for Tau Function and Mechanism
- (2017) Aranda R. Duan et al. JOURNAL OF MOLECULAR BIOLOGY
- Bacterial co-expression of human Tau protein with protein kinase A and 14-3-3 for studies of 14-3-3/phospho-Tau interaction
- (2017) Kristina V. Tugaeva et al. PLoS One
- HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients
- (2017) Wenting Guo et al. Nature Communications
- Local Nucleation of Microtubule Bundles through Tubulin Concentration into a Condensed Tau Phase
- (2017) Amayra Hernández-Vega et al. Cell Reports
- The Distance between N and C Termini of Tau and of FTDP-17 Mutants Is Modulated by Microtubule Interactions in Living Cells
- (2017) Cristina Di Primio et al. Frontiers in Molecular Neuroscience
- EuroTau: towing scientists to tau without tautology
- (2017) Amrit Mudher et al. Acta Neuropathologica Communications
- Stability properties of neuronal microtubules
- (2016) Peter W. Baas et al. Cytoskeleton
- Do Cancer Drugs Counteract Neurodegeneration? Repurposing for Alzheimer’s Disease
- (2016) Fiammetta Monacelli et al. JOURNAL OF ALZHEIMERS DISEASE
- Regulation of Microtubule Assembly by Tau and not by Pin1
- (2016) Steffen Kutter et al. JOURNAL OF MOLECULAR BIOLOGY
- Microtubule-Tau Interaction as a Therapeutic Target for Alzheimer’s Disease
- (2016) Yanina Ivashko Pachima et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- A functional role for intrinsic disorder in the tau-tubulin complex
- (2016) Ana M. Melo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Microtubule stabilising peptides rescue tau phenotypes in-vivo
- (2016) Shmma Quraishe et al. Scientific Reports
- Folding of the Tau Protein on Microtubules
- (2015) Harindranath Kadavath et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Mechanistic Origin of Microtubule Dynamic Instability and Its Modulation by EB Proteins
- (2015) Rui Zhang et al. CELL
- Involvement of 14-3-3 in tubulin instability and impaired axon development is mediated by Tau
- (2015) Yuyoung Joo et al. FASEB JOURNAL
- Tau Binds to Multiple Tubulin Dimers with Helical Structure
- (2015) Xiao-Han Li et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits
- (2015) Sang-Won Min et al. NATURE MEDICINE
- Tau post-translational modifications in wild-type and human amyloid precursor protein transgenic mice
- (2015) Meaghan Morris et al. NATURE NEUROSCIENCE
- Stathmin Potentiates Vinflunine and Inhibits Paclitaxel Activity
- (2015) Soazig Malesinski et al. PLoS One
- Tau stabilizes microtubules by binding at the interface between tubulin heterodimers
- (2015) Harindranath Kadavath et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural Impact of Tau Phosphorylation at Threonine 231
- (2015) Martin Schwalbe et al. STRUCTURE
- Regulation of Microtubule Growth and Catastrophe: Unifying Theory and Experiment
- (2015) Hugo Bowne-Anderson et al. TRENDS IN CELL BIOLOGY
- Posttranslational modifications of α-tubulin in alzheimer disease
- (2015) Fan Zhang et al. Translational Neurodegeneration
- Nuclear Magnetic Resonance Analysis of the Acetylation Pattern of the Neuronal Tau Protein
- (2014) Amina Kamah et al. BIOCHEMISTRY
- High-Resolution Microtubule Structures Reveal the Structural Transitions in αβ-Tubulin upon GTP Hydrolysis
- (2014) Gregory M. Alushin et al. CELL
- Molecular Basis for Age-Dependent Microtubule Acetylation by Tubulin Acetyltransferase
- (2014) Agnieszka Szyk et al. CELL
- A Slow Dance for Microtubule Acetylation
- (2014) F. Jon Kull et al. CELL
- Quantitative Analysis of Tau-Microtubule Interaction Using FRET
- (2014) Isabelle Maïo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mechanism of Tau-Promoted Microtubule Assembly As Probed by NMR Spectroscopy
- (2014) Benoît Gigant et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Single-molecule tracking of tau reveals fast kiss-and-hop interaction with microtubules in living neurons
- (2014) Dennis Janning et al. MOLECULAR BIOLOGY OF THE CELL
- The NAP motif of activity-dependent neuroprotective protein (ADNP) regulates dendritic spines through microtubule end binding proteins
- (2014) S Oz et al. MOLECULAR PSYCHIATRY
- Increasing microtubule acetylation rescues axonal transport and locomotor deficits caused by LRRK2 Roc-COR domain mutations
- (2014) Vinay K. Godena et al. Nature Communications
- Histone deacetylase 6 inhibition improves memory and reduces total tau levels in a mouse model of tau deposition
- (2014) Maj-Linda Selenica et al. Alzheimers Research & Therapy
- Acetylated Tau Neuropathology in Sporadic and Hereditary Tauopathies
- (2013) David J. Irwin et al. AMERICAN JOURNAL OF PATHOLOGY
- Interaction of 14-3-3ζ with Microtubule-Associated Protein Tau within Alzheimer’s Disease Neurofibrillary Tangles
- (2013) Hamid Y. Qureshi et al. BIOCHEMISTRY
- FRET and FRAP imaging: Approaches to characterise tau and stathmin interactions with microtubules in cells
- (2013) Roqiya Nouar et al. BIOLOGY OF THE CELL
- Molecular mechanisms of Tau binding to microtubules and its role in microtubule dynamics in live cells
- (2013) G. Breuzard et al. JOURNAL OF CELL SCIENCE
- Tau protein as a potential predictive marker in epithelial ovarian cancer patients treated with paclitaxel/platinum first-line chemotherapy
- (2013) Marta Smoter et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Tau proteins expressions in advanced breast cancer and its significance in taxane-containing neoadjuvant chemotherapy
- (2013) Zhi-hua Li et al. MEDICAL ONCOLOGY
- NAP (davunetide) rescues neuronal dysfunction in a Drosophila model of tauopathy
- (2013) S Quraishe et al. MOLECULAR PSYCHIATRY
- HDAC6 mutations rescue human tau-induced microtubule defects in Drosophila
- (2013) Y. Xiong et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Predictive Atomic Resolution Descriptions of Intrinsically Disordered hTau40 and α-Synuclein in Solution from NMR and Small Angle Scattering
- (2013) Martin Schwalbe et al. STRUCTURE
- FTDP-17 Tau Mutations Induce Distinct Effects on Aggregation and Microtubule Interactions
- (2012) Benjamin Combs et al. BIOCHEMISTRY
- Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies
- (2012) David J. Irwin et al. BRAIN
- Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease
- (2012) Nambirajan Govindarajan et al. EMBO Molecular Medicine
- Tau Protein Diffuses along the Microtubule Lattice
- (2012) Maike H. Hinrichs et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end
- (2012) Ludovic Pecqueur et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Systematic Identification of Tubulin-interacting Fragments of the Microtubule-associated Protein Tau Leads to a Highly Efficient Promoter of Microtubule Assembly
- (2011) Caroline Fauquant et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Determinants That Govern Microtubule Assembly from the Atomic Structure of GTP-Tubulin
- (2011) Agata Nawrotek et al. JOURNAL OF MOLECULAR BIOLOGY
- Structural characterization by nuclear magnetic resonance of the impact of phosphorylation in the proline-rich region of the disordered Tau protein
- (2011) Nathalie Sibille et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- The acetylation of tau inhibits its function and promotes pathological tau aggregation
- (2011) Todd J. Cohen et al. Nature Communications
- Modulation of Protein-Protein Interactions as a Therapeutic Strategy for the Treatment of Neurodegenerative Tauopathies
- (2010) C. Ballatore et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Stathmin and Interfacial Microtubule Inhibitors Recognize a Naturally Curved Conformation of Tubulin Dimers
- (2010) Pascale Barbier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Acetylation of Tau Inhibits Its Degradation and Contributes to Tauopathy
- (2010) Sang-Won Min et al. NEURON
- The characterization of microtubule-stabilizing drugs as possible therapeutic agents for Alzheimer's disease and related tauopathies
- (2010) Kurt R. Brunden et al. PHARMACOLOGICAL RESEARCH
- Regulation of microtubule dynamic instability
- (2009) Babet van der Vaart et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Advances in tau-focused drug discovery for Alzheimer's disease and related tauopathies
- (2009) Kurt R. Brunden et al. NATURE REVIEWS DRUG DISCOVERY
- Inhibitors of Class 1 Histone Deacetylases Reverse Contextual Memory Deficits in a Mouse Model of Alzheimer's Disease
- (2009) Mark Kilgore et al. NEUROPSYCHOPHARMACOLOGY
- Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
- (2009) Marco D Mukrasch et al. PLOS BIOLOGY
- Alzheimer disease specific phosphoepitopes of Tau interfere with assembly of tubulin but not binding to microtubules
- (2008) Laziza Amniai et al. FASEB JOURNAL
- FTDP-17 Mutations in Tau Alter the Regulation of Microtubule Dynamics
- (2008) Adria C. LeBoeuf et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Complementary dimerization of microtubule-associated tau protein: Implications for microtubule bundling and tau-mediated pathogenesis
- (2008) K. J. Rosenberg et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions
- (2007) Peter Tompa et al. TRENDS IN BIOCHEMICAL SCIENCES
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