A Novel Tool for the Generation of Conditional Knockouts To Study Gene Function across the Plasmodium falciparum Life Cycle

Challenges and recent progress in drug discovery for tropical diseases

(2018) Manu De Rycker et al.   NATURE

Open-source discovery of chemical leads for next-generation chemoprotective antimalarials

(2018) Yevgeniya Antonova-Koch et al.   SCIENCE

A genetic system to study Plasmodium falciparum protein function

(2017) Jakob Birnbaum et al.   NATURE METHODS

Essential Role of the PfRh5/PfRipr/CyRPA Complex during Plasmodium falciparum Invasion of Erythrocytes

(2016) Jennifer C. Volz et al.   Cell Host & Microbe

Regulation and Essentiality of the StAR-related Lipid Transfer (START) Domain-containing Phospholipid Transfer Protein PFA0210c in Malaria Parasites

(2016) Ross J. Hill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Routine in vitro culture of P. falciparum gametocytes to evaluate novel transmission-blocking interventions

(2016) Michael J Delves et al.   Nature Protocols

Synthetic RNA–protein modules integrated with native translation mechanisms to control gene expression in malaria parasites

(2016) Suresh M. Ganesan et al.   Nature Communications

A versatile strategy for rapid conditional genome engineering using loxP sites in a small synthetic intron in Plasmodium falciparum

(2016) Matthew L. Jones et al.   Scientific Reports

Molecular Analysis of Pfs47-Mediated Plasmodium Evasion of Mosquito Immunity

(2016) Gaspar E. Canepa et al.   PLoS One

Processing of Plasmodium falciparum Merozoite Surface Protein MSP1 Activates a Spectrin-Binding Function Enabling Parasite Egress from RBCs

(2015) Sujaan Das et al.   Cell Host & Microbe

Advances in molecular genetic systems in malaria

(2015) Tania F. de Koning-Ward et al.   NATURE REVIEWS MICROBIOLOGY

A New Role of the Mosquito Complement-like Cascade in Male Fertility in Anopheles gambiae

(2015) Julien Pompon et al.   PLOS BIOLOGY

Conditional expression of apical membrane antigen 1 inPlasmodium falciparumshows it is required for erythrocyte invasion by merozoites

(2014) Alan Yap et al.   CELLULAR MICROBIOLOGY

Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum

(2014) Marije C Behet et al.   MALARIA JOURNAL

Versatile control of Plasmodium falciparum gene expression with an inducible protein–RNA interaction

(2014) Stephen J. Goldfless et al.   Nature Communications

Male and Female Plasmodium falciparum Mature Gametocytes Show Different Responses to Antimalarial Drugs

(2013) Michael J. Delves et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Robust inducible Cre recombinase activity in the human malaria parasitePlasmodium falciparumenables efficient gene deletion within a single asexual erythrocytic growth cycle

(2013) Christine R. Collins et al.   MOLECULAR MICROBIOLOGY

Inducible Knockdown of Plasmodium Gene Expression Using the glmS Ribozyme

(2013) Parichat Prommana et al.   PLoS One

The Human Malaria Parasite Pfs47 Gene Mediates Evasion of the Mosquito Immune System

(2013) A. Molina-Cruz et al.   SCIENCE

A Tetracycline-Repressible Transactivator System to Study Essential Genes in Malaria Parasites

(2012) Paco Pino et al.   Cell Host & Microbe

Icy: an open bioimage informatics platform for extended reproducible research

(2012) Fabrice de Chaumont et al.   NATURE METHODS

Directional gene expression and antisense transcripts in sexual and asexual stages of Plasmodium falciparum

(2011) María J López-Barragán et al.   BMC GENOMICS

Independent Roles of Apical Membrane Antigen 1 and Rhoptry Neck Proteins during Host Cell Invasion by Apicomplexa

(2011) Donatella Giovannini et al.   Cell Host & Microbe

Plasmodium falciparum FIKK Kinase Members Target Distinct Components of the Erythrocyte Membrane

(2010) Marta C. Nunes et al.   PLoS One

Removal of Heterologous Sequences from Plasmodium falciparum Mutants Using FLPe-Recombinase

(2010) Ben C. L. van Schaijk et al.   PLoS One

Protein Kinase A Dependent Phosphorylation of Apical Membrane Antigen 1 Plays an Important Role in Erythrocyte Invasion by the Malaria Parasite

(2010) Kerstin Leykauf et al.   PLoS Pathogens

Characterisation of Plasmodium invasive organelles; an ookinete microneme proteome

(2009) Kalpana Lal et al.   PROTEOMICS

Functional Analysis of the Leading Malaria Vaccine Candidate AMA-1 Reveals an Essential Role for the Cytoplasmic Domain in the Invasion Process

(2009) Moritz Treeck et al.   PLoS Pathogens