Myeloid and CD4 T Cells Comprise the Latent Reservoir in Antiretroviral Therapy-Suppressed SIVmac251-Infected Macaques

HIV-1 reservoirs in urethral macrophages of patients under suppressive antiretroviral therapy

(2019) Yonatan Ganor et al.   Nature Microbiology

Infectious virus persists in CD4+ T cells and macrophages in ART-suppressed SIV-infected Macaques

(2019) Celina M. Abreu et al.   JOURNAL OF VIROLOGY

Performance Characteristics of Cerebrospinal Fluid Cytology: An Analysis of Responses From the College of American Pathologists Nongynecologic Cytopathology Education Program

(2018) Z. Laura Tabatabai et al.   ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

Temporal/compartmental changes in viral RNA and neuronal injury in a primate model of NeuroAIDS

(2018) R. Gilberto González et al.   PLoS One

Correlates of Protection Against SIV mac251 Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors

(2018) Steven Tuyishime et al.   EBioMedicine

No recovery of replication-competent HIV-1 from human liver macrophages

(2018) Abraham J. Kandathil et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophages but not Astrocytes Harbor HIV DNA in the Brains of HIV-1-Infected Aviremic Individuals on Suppressive Antiretroviral Therapy

(2018) Allen Ko et al.   Journal of Neuroimmune Pharmacology

An SIV/macaque model targeted to study HIV-associated neurocognitive disorders

(2017) Sarah E. Beck et al.   JOURNAL OF NEUROVIROLOGY

Identification of Emerging Macrophage-Tropic HIV-1 R5 Variants in Brain Tissue of AIDS Patients without Severe Neurological Complications

(2017) Maria Paz Gonzalez-Perez et al.   JOURNAL OF VIROLOGY

Insights into the Impact of CD8 + Immune Modulation on Human Immunodeficiency Virus Evolutionary Dynamics in Distinct Anatomical Compartments by Using Simian Immunodeficiency Virus-Infected Macaque Models of AIDS Progression

(2017) Brittany Rife Magalis et al.   JOURNAL OF VIROLOGY

HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy

(2017) Jenna B Honeycutt et al.   NATURE MEDICINE

Brain Macrophages in Simian Immunodeficiency Virus-Infected, Antiretroviral-Suppressed Macaques: a Functional Latent Reservoir

(2017) Claudia R. Avalos et al.   mBio

Role of Monocyte/Macrophages during HIV/SIV Infection in Adult and Pediatric Acquired Immune Deficiency Syndrome

(2017) Kristen M. Merino et al.   Frontiers in Immunology

Macrophages and HIV-1: An Unhealthy Constellation

(2016) Quentin J. Sattentau et al.   Cell Host & Microbe

Quantitation of Productively Infected Monocytes and Macrophages of Simian Immunodeficiency Virus-Infected Macaques

(2016) Claudia R. Avalos et al.   JOURNAL OF VIROLOGY

Magnitude and Quality of Cytokine and Chemokine Storm during Acute Infection Distinguish Nonprogressive and Progressive Simian Immunodeficiency Virus Infections of Nonhuman Primates

(2016) Sheila M. Keating et al.   JOURNAL OF VIROLOGY

Proliferation of Perivascular Macrophages Contributes to the Development of Encephalitic Lesions in HIV-Infected Humans and in SIV-Infected Macaques

(2016) Adam R. Filipowicz et al.   Scientific Reports

Paving the path to HIV neurotherapy: Predicting SIV CNS disease

(2015) Sarah E. Beck et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Increased monocyte turnover is associated with interstitial macrophage accumulation and pulmonary tissue damage in SIV-infected rhesus macaques

(2015) Yanhui Cai et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Role of the macrophage in HIV-associated neurocognitive disorders and other comorbidities in patients on effective antiretroviral treatment

(2015) Jay Rappaport et al.   JOURNAL OF NEUROVIROLOGY

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

(2015) D. H. Barouch et al.   SCIENCE

Elevated Numbers of CD163+ Macrophages in Hearts of Simian Immunodeficiency Virus-Infected Monkeys Correlate with Cardiac Pathology and Fibrosis

(2014) Joshua A. Walker et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Antiretroviral-Free HIV-1 Remission and Viral Rebound After Allogeneic Stem Cell Transplantation

(2014) Timothy J. Henrich et al.   ANNALS OF INTERNAL MEDICINE

Macrophage Infection via Selective Capture of HIV-1-Infected CD4+ T Cells

(2014) Amy E. Baxter et al.   Cell Host & Microbe

Spatiotemporal dynamics of simian immunodeficiency virus brain infection in CD8+ lymphocyte-depleted rhesus macaques with neuroAIDS

(2014) S. L. Strickland et al.   JOURNAL OF GENERAL VIROLOGY

HIV-1 target cells in the CNS

(2014) Sarah B. Joseph et al.   JOURNAL OF NEUROVIROLOGY

Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys

(2014) James B. Whitney et al.   NATURE

Analysis of Multiply Spliced Transcripts in Lymphoid Tissue Reservoirs of Rhesus Macaques Infected with RT-SHIV during HAART

(2014) Jesse D. Deere et al.   PLoS One

Residual Viremia in an RT-SHIV Rhesus Macaque HAART Model Marked by the Presence of a Predominant Plasma Clone and a Lack of Viral Evolution

(2014) Robert C. Kauffman et al.   PLoS One

CD4 Depletion in SIV-Infected Macaques Results in Macrophage and Microglia Infection with Rapid Turnover of Infected Cells

(2014) Luca Micci et al.   PLoS Pathogens

Infection-Induced Changes in Hematopoiesis

(2013) A. G. Zaretsky et al.   JOURNAL OF IMMUNOLOGY

Long-Term Reduction in Peripheral Blood HIV Type 1 Reservoirs Following Reduced-Intensity Conditioning Allogeneic Stem Cell Transplantation

(2013) T. J. Henrich et al.   JOURNAL OF INFECTIOUS DISEASES

Protection Afforded by an HIV Vaccine Candidate in Macaques Depends on the Dose of SIVmac251 at Challenge Exposure

(2013) M. Vaccari et al.   JOURNAL OF VIROLOGY

Absence of Detectable HIV-1 Viremia after Treatment Cessation in an Infant

(2013) Deborah Persaud et al.   NEW ENGLAND JOURNAL OF MEDICINE

HIV-1 infection, response to treatment and establishment of viral latency in a novel humanized T cell-only mouse (TOM) model

(2013) Jenna B Honeycutt et al.   Retrovirology

Beyond Stem Cells: Self-Renewal of Differentiated Macrophages

(2013) M. H. Sieweke et al.   SCIENCE

Experimental Analysis of Sources of Error in Evolutionary Studies Based on Roche/454 Pyrosequencing of Viral Genomes

(2012) E. A. Becker et al.   Genome Biology and Evolution

Neurovirological Correlation With HIV-Associated Neurocognitive Disorders and Encephalitis in a HAART-Era Cohort

(2012) Benjamin B. Gelman et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Expansion of a subset of CD14high CD16neg CCR2low/neg monocytes functionally similar to myeloid-derived suppressor cells during SIV and HIV infection

(2012) Lucio Gama et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Macaque studies of vaccine and microbicide combinations for preventing HIV-1 sexual transmission

(2012) D. H. Barouch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer

(2012) Ende Zhao et al.   OncoImmunology

Early Minocycline Treatment Prevents a Decrease in Striatal Dopamine in an SIV Model of HIV-Associated Neurological Disease

(2011) Kelly A. Meulendyke et al.   Journal of Neuroimmune Pharmacology

HIV-1 Replication in the Central Nervous System Occurs in Two Distinct Cell Types

(2011) Gretja Schnell et al.   PLoS Pathogens

Impact of Short-Term Combined Antiretroviral Therapy on Brain Virus Burden in Simian Immunodeficiency Virus-Infected and CD8+ Lymphocyte-Depleted Rhesus Macaques

(2010) Lakshmanan Annamalai et al.   AMERICAN JOURNAL OF PATHOLOGY

Simian Immunodeficiency Virus–Infected Macaques Treated with Highly Active Antiretroviral Therapy Have Reduced Central Nervous System Viral Replication and Inflammation but Persistence of Viral DNA

(2010) M. Christine Zink et al.   JOURNAL OF INFECTIOUS DISEASES

Macrophages: do they impact AIDS progression more than CD4 T cells?

(2010) Marcelo J. Kuroda   JOURNAL OF LEUKOCYTE BIOLOGY

HIV DNA in circulating monocytes as a mechanism to dementia and other HIV complications

(2010) Victor G. Valcour et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Initiation of HAART during acute simian immunodeficiency virus infection rapidly controls virus replication in the CNS by enhancing immune activity and preserving protective immune responses

(2010) David R. Graham et al.   JOURNAL OF NEUROVIROLOGY

Proton Magnetic Resonance Spectroscopy Reveals Neuroprotection by Oral Minocycline in a Nonhuman Primate Model of Accelerated NeuroAIDS

(2010) Eva-Maria Ratai et al.   PLoS One

A simian immunodeficiency virus macaque model of highly active antiretroviral treatment: viral latency in the periphery and the central nervous system

(2010) Janice E Clements et al.   Current Opinion in HIV and AIDS

A Simian Immunodeficiency Virus-Infected Macaque Model To Study Viral Reservoirs That Persist during Highly Active Antiretroviral Therapy

(2009) J. B. Dinoso et al.   JOURNAL OF VIROLOGY

Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques

(2008) William R. Wikoff et al.   JOURNAL OF CLINICAL INVESTIGATION

The accelerated simian immunodeficiency virus macaque model of human immunodeficiency virus–associated neurological disease: From mechanism to treatment

(2008) Janice E Clements et al.   JOURNAL OF NEUROVIROLOGY

Metabolic markers of neuronal injury correlate with SIV CNS disease severity and inoculum in the macaque model of neuroAIDS

(2008) Margaret R. Lentz et al.   MAGNETIC RESONANCE IN MEDICINE