The Rich Tapestry of Bacterial Protein Translocation Systems

Motor properties of PilT-independent type 4 pilus retraction in gonococci

(2019) Robert Zöllner et al.   JOURNAL OF BACTERIOLOGY

In situ and high‐resolution cryo‐EM structure of a bacterial type VI secretion system membrane complex

(2019) Chiara Rapisarda et al.   EMBO JOURNAL

In situ structures of polar and lateral flagella revealed by cryo-electron tomography

(2019) Shiwei Zhu et al.   JOURNAL OF BACTERIOLOGY

Type IV pili: dynamics, biophysics and functional consequences

(2019) Lisa Craig et al.   NATURE REVIEWS MICROBIOLOGY

In Situ Molecular Architecture of the Helicobacter pylori Cag Type IV Secretion System

(2019) Bo Hu et al.   mBio

Stenotrophomonas maltophilia Encodes a VirB/D4 Type IV Secretion System That Modulates Apoptosis in Human Cells and Promotes Competition Against Heterologous Bacteria Including Pseudomonas aeruginosa

(2019) Megan Y. Nas et al.   INFECTION AND IMMUNITY

Protein-Injection Machines in Bacteria

(2018) Jorge E. Galán et al.   CELL

Secretins revealed: structural insights into the giant gated outer membrane portals of bacteria

(2018) Dorothy D Majewski et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

An N-Terminal Retention Module Anchors the Giant Adhesin LapA of Pseudomonas fluorescens at the Cell Surface: a Novel Subfamily of Type I Secretion Systems

(2018) T. Jarrod Smith et al.   JOURNAL OF BACTERIOLOGY

Type 1 Does The Two-Step: Type 1 Secretion Substrates With A Functional Periplasmic Intermediate

(2018) Timothy J. Smith et al.   JOURNAL OF BACTERIOLOGY

The role of functional amyloids in bacterial virulence

(2018) Nani Van Gerven et al.   JOURNAL OF MOLECULAR BIOLOGY

Contractile injection systems of bacteriophages and related systems

(2018) Nicholas M. I. Taylor et al.   MOLECULAR MICROBIOLOGY

Type IV secretion in Gram-negative and Gram-positive bacteria

(2018) Elisabeth Grohmann et al.   MOLECULAR MICROBIOLOGY

Structure of the core of the type III secretion system export apparatus

(2018) Lucas Kuhlen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of the core of the type III secretion system export apparatus

(2018) Lucas Kuhlen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Role of the Mycobacterium marinum ESX-1 Secretion System in Sliding Motility and Biofilm Formation

(2018) Li-Yin Lai et al.   Frontiers in Microbiology

A unique cytoplasmic ATPase complex defines the Legionella pneumophila type IV secretion channel

(2018) David Chetrit et al.   Nature Microbiology

Retraction of DNA-bound type IV competence pili initiates DNA uptake during natural transformation in Vibrio cholerae

(2018) Courtney K. Ellison et al.   Nature Microbiology

Two pKM101-Encoded Proteins, the Pilus-Tip Protein TraC and Pep, Assemble on the Escherichia coli Cell Surface as Adhesins Required for Efficient Conjugative DNA Transfer

(2018) Christian Gonzalez-Rivera et al.   MOLECULAR MICROBIOLOGY

Cryo-EM analysis of the T3S injectisome reveals the structure of the needle and open secretin

(2018) J. Hu et al.   Nature Communications

Type 9 secretion system structures reveal a new protein transport mechanism

(2018) Frédéric Lauber et al.   NATURE

Visualization of the type III secretion mediated Salmonella–host cell interface using cryo-electron tomography

(2018) Donghyun Park et al.   eLife

Cryo-EM structure of the bacteria-killing type IV secretion system core complex from Xanthomonas citri

(2018) Germán G. Sgro et al.   Nature Microbiology

Biogenesis and structure of a type VI secretion baseplate

(2018) Yassine Cherrak et al.   Nature Microbiology

Untangling Flavobacterium johnsoniae Gliding Motility and Protein Secretion

(2017) Joseph J. Johnston et al.   JOURNAL OF BACTERIOLOGY

Structural basis for substrate selection by the translocation and assembly module of the β-barrel assembly machinery

(2017) Rebecca S. Bamert et al.   MOLECULAR MICROBIOLOGY

Versatile cell surface structures of archaea

(2017) Paushali Chaudhury et al.   MOLECULAR MICROBIOLOGY

Type IX secretion: the generation of bacterial cell surface coatings involved in virulence, gliding motility and the degradation of complex biopolymers

(2017) Paul D. Veith et al.   MOLECULAR MICROBIOLOGY

Job contenders: roles of the β-barrel assembly machinery and the translocation and assembly module in autotransporter secretion

(2017) Cécile Albenne et al.   MOLECULAR MICROBIOLOGY

Assembly, structure, function and regulation of type III secretion systems

(2017) Wanyin Deng et al.   NATURE REVIEWS MICROBIOLOGY

Manganese scavenging and oxidative stress response mediated by type VI secretion system inBurkholderia thailandensis

(2017) Meiru Si et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obstruction of pilus retraction stimulates bacterial surface sensing

(2017) Courtney K. Ellison et al.   SCIENCE

Adaptor Proteins of Type VI Secretion System Effectors

(2017) Daniel Unterweger et al.   TRENDS IN MICROBIOLOGY

Structural Basis of Type 2 Secretion System Engagement between the Inner and Outer Bacterial Membranes

(2017) Iain D. Hay et al.   mBio

A Pseudomonas T6SS effector recruits PQS-containing outer membrane vesicles for iron acquisition

(2017) Jinshui Lin et al.   Nature Communications

Cryo-EM structure of the extended type VI secretion system sheath–tube complex

(2017) Jing Wang et al.   Nature Microbiology

Structure of the calcium-dependent type 2 secretion pseudopilus

(2017) Aracelys López-Castilla et al.   Nature Microbiology

Structure of a 1.5-MDa adhesin that binds its Antarctic bacterium to diatoms and ice

(2017) Shuaiqi Guo et al.   Science Advances

PorV is an Outer Membrane Shuttle Protein for the Type IX Secretion System

(2017) Michelle D. Glew et al.   Scientific Reports

Mechanical Unfolding of an Autotransporter Passenger Protein Reveals the Secretion Starting Point and Processive Transport Intermediates

(2016) Marian Baclayon et al.   ACS Nano

The Self-Identity Protein IdsD Is Communicated between Cells in Swarming Proteus mirabilis Colonies

(2016) Christina C. Saak et al.   JOURNAL OF BACTERIOLOGY

ESX secretion systems: mycobacterial evolution to counter host immunity

(2016) Matthias I. Gröschel et al.   NATURE REVIEWS MICROBIOLOGY

Protein export through the bacterial Sec pathway

(2016) Alexandra Tsirigotaki et al.   NATURE REVIEWS MICROBIOLOGY

SalmonellaTyphimurium utilizes a T6SS-mediated antibacterial weapon to establish in the host gut

(2016) Thibault G. Sana et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis of Pullulanase Membrane Binding and Secretion Revealed by X-Ray Crystallography, Molecular Dynamics and Biochemical Analysis

(2016) Alexandra East et al.   STRUCTURE

The outer-membrane export signal of Porphyromonas gingivalis type IX secretion system (T9SS) is a conserved C-terminal β-sandwich domain

(2016) Iñaki de Diego et al.   Scientific Reports

Effective assembly of fimbriae in Escherichia coli depends on the translocation assembly module nanomachine

(2016) Christopher Stubenrauch et al.   Nature Microbiology

The Twin-Arginine Protein Translocation Pathway

(2015) Ben C. Berks   Annual Review of Biochemistry

Structure of the Type VI Secretion System Contractile Sheath

(2015) Mikhail Kudryashev et al.   CELL

Molecular weaponry: diverse effectors delivered by the Type VI secretion system

(2015) Juliana Alcoforado Diniz et al.   CELLULAR MICROBIOLOGY

Towards a model for Flavobacterium gliding

(2015) Abhishek Shrivastava et al.   CURRENT OPINION IN MICROBIOLOGY

SepD/SepL-Dependent Secretion Signals of the Type III Secretion System Translocator Proteins in Enteropathogenic Escherichia coli

(2015) Wanyin Deng et al.   JOURNAL OF BACTERIOLOGY

The Bacterial Curli System Possesses a Potent and Selective Inhibitor of Amyloid Formation

(2015) Margery L. Evans et al.   MOLECULAR CELL

Assembly of the secretion pores GspD, Wza and CsgG into bacterial outer membranes does not require the Omp85 proteins BamA or TamA

(2015) Rhys A. Dunstan et al.   MOLECULAR MICROBIOLOGY

Secretion systems in Gram-negative bacteria: structural and mechanistic insights

(2015) Tiago R. D. Costa et al.   NATURE REVIEWS MICROBIOLOGY

Urinary tract infections: epidemiology, mechanisms of infection and treatment options

(2015) Ana L. Flores-Mireles et al.   NATURE REVIEWS MICROBIOLOGY

The pilus usher controls protein interactions via domain masking and is functional as an oligomer

(2015) Glenn T Werneburg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Type III secretion systems: the bacterial flagellum and the injectisome

(2015) Andreas Diepold et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Visualization of the type III secretion sorting platform ofShigella flexneri

(2015) Bo Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial killing via a type IV secretion system

(2015) Diorge P. Souza et al.   Nature Communications

The pilus usher controls protein interactions via domain masking and is functional as an oligomer

(2015) Glenn T Werneburg et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Directionality of substrate translocation of the hemolysin A Type I secretion system

(2015) Michael H. H. Lenders et al.   Scientific Reports

The Type VI Secretion TssEFGK-VgrG Phage-Like Baseplate Is Recruited to the TssJLM Membrane Complex via Multiple Contacts and Serves As Assembly Platform for Tail Tube/Sheath Polymerization

(2015) Yannick R. Brunet et al.   PLoS Genetics

Type VI Secretion System Transports Zn2+ to Combat Multiple Stresses and Host Immunity

(2015) Tietao Wang et al.   PLoS Pathogens

Architecture and assembly of the Type VI secretion system

(2014) Abdelrahim Zoued et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Secretion and functional display of fusion proteins through the curli biogenesis pathway

(2014) Nani Van Gerven et al.   MOLECULAR MICROBIOLOGY

Enterococcus faecalis pCF10-encoded surface proteins PrgA, PrgB (aggregation substance) and PrgC contribute to plasmid transfer, biofilm formation and virulence

(2014) Minny Bhatty et al.   MOLECULAR MICROBIOLOGY

Structure of a type IV secretion system

(2014) Harry H. Low et al.   NATURE

Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG

(2014) Parveen Goyal et al.   NATURE

Structure of the AcrAB–TolC multidrug efflux pump

(2014) Dijun Du et al.   NATURE

Type VI secretion system effectors: poisons with a purpose

(2014) Alistair B. Russell et al.   NATURE REVIEWS MICROBIOLOGY

WXG100 Protein Superfamily Consists of Three Subfamilies and Exhibits an α-Helical C-Terminal Conserved Residue Pattern

(2014) Christian Poulsen et al.   PLoS One

Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion

(2014) D. C. Ekiert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VgrG, Tae, Tle, and beyond: the versatile arsenal of Type VI secretion effectors

(2014) Eric Durand et al.   TRENDS IN MICROBIOLOGY

Mycobacterial Esx-3 Requires Multiple Components for Iron Acquisition

(2014) M. S. Siegrist et al.   mBio

Reconstitution of a nanomachine driving the assembly of proteins into bacterial outer membranes

(2014) Hsin-Hui Shen et al.   Nature Communications

Take five — Type VII secretion systems of Mycobacteria

(2013) Edith N.G. Houben et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

RNA Type III Secretion Signals That Require Hfq

(2013) G. S. Niemann et al.   JOURNAL OF BACTERIOLOGY

PrgK, a Multidomain Peptidoglycan Hydrolase, Is Essential for Conjugative Transfer of the Pheromone-Responsive Plasmid pCF10

(2013) J. A. Laverde Gomez et al.   JOURNAL OF BACTERIOLOGY

TraG Encoded by the pIP501 Type IV Secretion System Is a Two-Domain Peptidoglycan-Degrading Enzyme Essential for Conjugative Transfer

(2013) K. Arends et al.   JOURNAL OF BACTERIOLOGY

Haemolysin Coregulated Protein Is an Exported Receptor and Chaperone of Type VI Secretion Substrates

(2013) Julie M. Silverman et al.   MOLECULAR CELL

An alternative outer membrane secretion mechanism for an autotransporter protein lacking a C-terminal stable core

(2013) Richard N. Besingi et al.   MOLECULAR MICROBIOLOGY

Structure of a translocation signal domain mediating conjugative transfer by type IV secretion systems

(2013) Adam Redzej et al.   MOLECULAR MICROBIOLOGY

ClpV recycles VipA/VipB tubules and prevents non-productive tubule formation to ensure efficient type VI protein secretion

(2013) Nicole Kapitein et al.   MOLECULAR MICROBIOLOGY

PAAR-repeat proteins sharpen and diversify the type VI secretion system spike

(2013) Mikhail M. Shneider et al.   NATURE

Structure of a pathogenic type 3 secretion system in action

(2013) Julia Radics et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

F conjugation: Back to the beginning

(2013) Denis Arutyunov et al.   PLASMID

The ESX-3 Secretion System Is Necessary for Iron and Zinc Homeostasis in Mycobacterium tuberculosis

(2013) Agnese Serafini et al.   PLoS One

Charge-dependent secretion of an intrinsically disordered protein via the autotransporter pathway

(2013) W. Kang'ethe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanistic link between   barrel assembly and the initiation of autotransporter secretion

(2013) O. Pavlova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Helical flow of surface protein required for bacterial gliding motility

(2013) D. Nakane et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The expanding bacterial type IV secretion lexicon

(2013) Minny Bhatty et al.   RESEARCH IN MICROBIOLOGY

Pilus biogenesis at the outer membrane of Gram-negative bacterial pathogens

(2012) William J Allen et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Flavobacterium johnsoniae RemA Is a Mobile Cell Surface Lectin Involved in Gliding

(2012) A. Shrivastava et al.   JOURNAL OF BACTERIOLOGY

Ultrastructural Analysis of IpaD at the Tip of the Nascent MxiH Type III Secretion Apparatus of Shigella flexneri

(2012) Chelsea R. Epler et al.   JOURNAL OF MOLECULAR BIOLOGY

The C-Terminal Repeating Units of CsgB Direct Bacterial Functional Amyloid Nucleation

(2012) Neal D. Hammer et al.   JOURNAL OF MOLECULAR BIOLOGY

The type II secretion system: biogenesis, molecular architecture and mechanism

(2012) Konstantin V. Korotkov et al.   NATURE REVIEWS MICROBIOLOGY

General requirements for protein secretion by the F-like conjugation system R1

(2012) Silvia Lang et al.   PLASMID

Curli Functional Amyloid Systems Are Phylogenetically Widespread and Display Large Diversity in Operon and Protein Structure

(2012) Morten S. Dueholm et al.   PLoS One

General secretion signal for the mycobacterial type VII secretion pathway

(2012) M. H. Daleke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An RTX Transporter Tethers Its Unfolded Substrate during Secretion via a Unique N-Terminal Domain

(2012) Justin Lecher et al.   STRUCTURE

The ins and outs of pertussis toxin

(2011) Camille Locht et al.   FEBS Journal

CsgE is a curli secretion specificity factor that prevents amyloid fibre aggregation

(2011) Ashley A. Nenninger et al.   MOLECULAR MICROBIOLOGY

Crystal structure of the FimD usher bound to its cognate FimC–FimH substrate

(2011) Gilles Phan et al.   NATURE

Type VI secretion delivers bacteriolytic effectors to target cells

(2011) Alistair B. Russell et al.   NATURE

A Sorting Platform Determines the Order of Protein Secretion in Bacterial Type III Systems

(2011) M. Lara-Tejero et al.   SCIENCE

Three-Dimensional Model of Salmonella's Needle Complex at Subnanometer Resolution

(2011) O. Schraidt et al.   SCIENCE

Outer Membrane Targeting of Pseudomonas aeruginosa Proteins Shows Variable Dependence on the Components of Bam and Lol Machineries

(2011) H. H. Hoang et al.   mBio

Computational Prediction of Type III and IV Secreted Effectors in Gram-Negative Bacteria

(2010) Jason E. McDermott et al.   INFECTION AND IMMUNITY

Crystal Structure of a Full-Length Autotransporter

(2010) Bert van den Berg   JOURNAL OF MOLECULAR BIOLOGY

The differential affinity of the usher for chaperone-subunit complexes is required for assembly of complete pili

(2010) Qinyuan Li et al.   MOLECULAR MICROBIOLOGY

Organization and coordinated assembly of the type III secretion export apparatus

(2010) Samuel Wagner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane-associated DNA Transport Machines

(2010) B. Burton et al.   Cold Spring Harbor Perspectives in Biology

Roles of Periplasmic Chaperone Proteins in the Biogenesis of Serine Protease Autotransporters of Enterobacteriaceae

(2009) F. Ruiz-Perez et al.   JOURNAL OF BACTERIOLOGY

High-Force Generation Is a Conserved Property of Type IV Pilus Systems

(2009) M. Clausen et al.   JOURNAL OF BACTERIOLOGY

Structure of the outer membrane complex of a type IV secretion system

(2009) Vidya Chandran et al.   NATURE

A protein secretion system linked to bacteroidete gliding motility and pathogenesis

(2009) K. Sato et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interaction of an autotransporter passenger domain with BamA during its translocation across the bacterial outer membrane

(2009) Raffaele Ieva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insights into pilus assembly and secretion from the structure and functional characterization of usher PapC

(2009) Y. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Localized and efficient curli nucleation requires the chaperone-like amyloid assembly protein CsgF

(2009) Ashley A. Nenninger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mycobacterial Esx-3 is required for mycobactin-mediated iron acquisition

(2009) M. S. Siegrist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type VI secretion apparatus and phage tail-associated protein complexes share a common evolutionary origin

(2009) P. G. Leiman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of a Type IV Secretion System Core Complex

(2009) R. Fronzes et al.   SCIENCE

Fiber Formation across the Bacterial Outer Membrane by the Chaperone/Usher Pathway

(2008) Han Remaut et al.   CELL

The type VI secretion toolkit

(2008) Eric Cascales   EMBO REPORTS

SprB Is a Cell Surface Component of the Flavobacterium johnsoniae Gliding Motility Machinery

(2008) S. S. Nelson et al.   JOURNAL OF BACTERIOLOGY

Novel mechanism of outer membrane targeting of proteins in Gram-negative bacteria

(2008) Yann Ferrandez et al.   MOLECULAR MICROBIOLOGY

AgrobacteriumVirB10 domain requirements for type IV secretion and T pilus biogenesis

(2008) Simon J. Jakubowski et al.   MOLECULAR MICROBIOLOGY