Dietary inulin alters the gut microbiome, enhances systemic metabolism and reduces neuroinflammation in an APOE4 mouse model

Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study

(2018) Peter Parbo et al.   NEUROBIOLOGY OF DISEASE

Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes

(2018) Liping Zhao et al.   SCIENCE

Ketogenic diet enhances neurovascular function with altered gut microbiome in young healthy mice

(2018) David Ma et al.   Scientific Reports

The mechanistic link between health and gut microbiota diversity

(2018) Olaf F. A. Larsen et al.   Scientific Reports

Proteus spp. as Putative Gastrointestinal Pathogens

(2018) Amy L. Hamilton et al.   CLINICAL MICROBIOLOGY REVIEWS

A Natural Dietary Supplement with a Combination of Nutrients Prevents Neurodegeneration Induced by a High Fat Diet in Mice

(2018) Domenico Nuzzo et al.   Nutrients

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

(2017) Susanne Krasemann et al.   IMMUNITY

A Randomized, Double-Blind, Placebo-Controlled, Phase II Study of Oral ELND005 (scyllo-Inositol) in Young Adults with Down Syndrome without Dementia

(2017) Michael S. Rafii et al.   JOURNAL OF ALZHEIMERS DISEASE

Microbiome-Modulated Metabolites at the Interface of Host Immunity

(2017) Eran Blacher et al.   JOURNAL OF IMMUNOLOGY

EFAD transgenic mice as a human APOE relevant preclinical model of Alzheimer’s disease

(2017) Leon M. Tai et al.   JOURNAL OF LIPID RESEARCH

Prebiotics in the management of components of the metabolic syndrome

(2017) Sarah O’Connor et al.   MATURITAS

NAFLD and Atherosclerosis Are Prevented by a Natural Dietary Supplement Containing Curcumin, Silymarin, Guggul, Chlorogenic Acid and Inulin in Mice Fed a High-Fat Diet

(2017) Antonella Amato et al.   Nutrients

Apolipoprotein E4 and Insulin Resistance Interact to Impair Cognition and Alter the Epigenome and Metabolome

(2017) Lance A. Johnson et al.   Scientific Reports

Analysis of the gut microbiome and plasma short-chain fatty acid profiles in a spontaneous mouse model of metabolic syndrome

(2017) Kazuchika Nishitsuji et al.   Scientific Reports

Age Drives Distortion of Brain Metabolic, Vascular and Cognitive Functions, and the Gut Microbiome

(2017) Jared D. Hoffman et al.   Frontiers in Aging Neuroscience

Fiber-utilizing capacity varies in Prevotella- versus Bacteroides-dominated gut microbiota

(2017) Tingting Chen et al.   Scientific Reports

Microbiota modulation counteracts Alzheimer’s disease progression influencing neuronal proteolysis and gut hormones plasma levels

(2017) Laura Bonfili et al.   Scientific Reports

Reversal of cognitive decline in Alzheimer's disease

(2016) Dale Bredesen et al.   Aging-US

Apolipoprotein E4 association with metabolic syndrome depends on body fatness

(2016) Elena Torres-Perez et al.   ATHEROSCLEROSIS

A Dietary Fiber-Deprived Gut Microbiota Degrades the Colonic Mucus Barrier and Enhances Pathogen Susceptibility

(2016) Mahesh S. Desai et al.   CELL

Myo-inositol changes precede amyloid pathology and relate toAPOEgenotype in Alzheimer disease

(2016) Olga Voevodskaya et al.   NEUROLOGY

Butyrate, neuroepigenetics and the gut microbiome: Can a high fiber diet improve brain health?

(2016) Megan W. Bourassa et al.   NEUROSCIENCE LETTERS

Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host Crosstalk

(2016) Kalaimathi Govindarajan et al.   PLoS One

Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease

(2016) Myles R. Minter et al.   Scientific Reports

Metabolic and Non-Cognitive Manifestations of Alzheimer’s Disease: The Hypothalamus as Both Culprit and Target of Pathology

(2015) Makoto Ishii et al.   Cell Metabolism

Dietary Fiber-Induced Improvement in Glucose Metabolism Is Associated with Increased Abundance of Prevotella

(2015) Petia Kovatcheva-Datchary et al.   Cell Metabolism

Deconstructing the Polymerase Chain Reaction: Understanding and Correcting Bias Associated with Primer Degeneracies and Primer-Template Mismatches

(2015) Stefan J. Green et al.   PLoS One

Specialized Metabolites from the Microbiome in Health and Disease

(2014) Gil Sharon et al.   Cell Metabolism

Age-Related Brain Expression and Regulation of the Chemokine CCL4/MIP-1β in APP/PS1 Double-Transgenic Mice

(2014) Min Zhu et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Regulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gut

(2014) S. A. Joyce et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Amyloid-β and Tau

(2014) George S. Bloom   JAMA Neurology

New roles for Fc receptors in neurodegeneration-the impact on Immunotherapy for Alzheimer's Disease

(2014) James P. Fuller et al.   Frontiers in Neuroscience

PEAR: a fast and accurate Illumina Paired-End reAd mergeR

(2013) J. Zhang et al.   BIOINFORMATICS

The Effect of Dietary Prebiotics and Probiotics on Body Weight, Large Intestine Indices, and Fecal Bile Acid Profile in Wild Type and IL10−/− Mice

(2013) Shiu-Ming Kuo et al.   PLoS One

Effects of High Performance Inulin Supplementation on Glycemic Control and Antioxidant Status in Women with Type 2 Diabetes

(2013) Bahram Pourghassem Gargari et al.   Diabetes & Metabolism Journal

Gut Microbiota Composition and Activity in Relation to Host Metabolic Phenotype and Disease Risk

(2012) Elaine Holmes et al.   Cell Metabolism

APOE4-specific Changes in Aβ Accumulation in a New Transgenic Mouse Model of Alzheimer Disease

(2012) Katherine L. Youmans et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Host-Gut Microbiota Metabolic Interactions

(2012) J. K. Nicholson et al.   SCIENCE

An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea

(2011) Daniel McDonald et al.   ISME Journal

Search and clustering orders of magnitude faster than BLAST

(2010) Robert C. Edgar   BIOINFORMATICS

Gut microbial diversity is reduced by the probiotic VSL#3 and correlates with decreased TNBS-induced colitis

(2010) Joshua M. Uronis et al.   INFLAMMATORY BOWEL DISEASES

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Organization of GC/MS and LC/MS metabolomics data into chemical libraries

(2010) Corey D DeHaven et al.   Journal of Cheminformatics

Integrated, Nontargeted Ultrahigh Performance Liquid Chromatography/Electrospray Ionization Tandem Mass Spectrometry Platform for the Identification and Relative Quantification of the Small-Molecule Complement of Biological Systems

(2009) Anne M. Evans et al.   ANALYTICAL CHEMISTRY

The Role of Metabolic Disorders in Alzheimer Disease and Vascular Dementia

(2009) Suzanne Craft   ARCHIVES OF NEUROLOGY

Ecological Role of Lactobacilli in the Gastrointestinal Tract: Implications for Fundamental and Biomedical Research

(2008) J. Walter   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Synthesis of scyllo-inositol derivatives and their effects on amyloid beta peptide aggregation

(2008) Yedi Sun et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice

(2008) S. Hauptmann et al.   NEUROBIOLOGY OF AGING