Antibiotic-induced perturbations in gut microbial diversity influences neuro-inflammation and amyloidosis in a murine model of Alzheimer’s disease

A gut (microbiome) feeling about the brain

(2016) Eoin Sherwin et al.   CURRENT OPINION IN GASTROENTEROLOGY

Peripheral Lymphoid Volume Expansion and Maintenance Are Controlled by Gut Microbiota via RALDH+ Dendritic Cells

(2016) Zongde Zhang et al.   IMMUNITY

Effects of Diurnal Variation of Gut Microbes and High-Fat Feeding on Host Circadian Clock Function and Metabolism

(2015) Vanessa Leone et al.   Cell Host & Microbe

Pancreatic β-Cells Limit Autoimmune Diabetes via an Immunoregulatory Antimicrobial Peptide Expressed under the Influence of the Gut Microbiota

(2015) Jia Sun et al.   IMMUNITY

The contribution of neuroinflammation to amyloid toxicity in Alzheimer's disease

(2015) Myles R. Minter et al.   JOURNAL OF NEUROCHEMISTRY

Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease

(2015) M A Lalli et al.   MOLECULAR PSYCHIATRY

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Il10 Deficiency Rebalances Innate Immunity to Mitigate Alzheimer-Like Pathology

(2015) Marie-Victoire Guillot-Sestier et al.   NEURON

IL-10 Alters Immunoproteostasis in APP Mice, Increasing Plaque Burden and Worsening Cognitive Behavior

(2015) Paramita Chakrabarty et al.   NEURON

Near-infrared fluorescence molecular imaging of amyloid beta species and monitoring therapy in animal models of Alzheimer’s disease

(2015) Xueli Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breaking immune tolerance by targeting Foxp3+ regulatory T cells mitigates Alzheimer’s disease pathology

(2015) Kuti Baruch et al.   Nature Communications

Murine versus human apolipoprotein E4: differential facilitation of and co-localization in cerebral amyloid angiopathy and amyloid plaques in APP transgenic mouse models

(2015) Fan Liao et al.   Acta Neuropathologica Communications

Soluble γ-Secretase Modulators Selectively Inhibit the Production of the 42-Amino Acid Amyloid β Peptide Variant and Augment the Production of Multiple Carboxy-Truncated Amyloid β Species

(2014) Steven L. Wagner et al.   BIOCHEMISTRY

The Binding of Apolipoprotein E to Oligomers and Fibrils of Amyloid-β Alters the Kinetics of Amyloid Aggregation

(2014) Kanchan Garai et al.   BIOCHEMISTRY

Systemic inflammation regulates microglial responses to tissue damagein vivo

(2014) Stefka Gyoneva et al.   GLIA

Anti-ApoE Antibody Given after Plaque Onset Decreases A  Accumulation and Improves Brain Function in a Mouse Model of A  Amyloidosis

(2014) F. Liao et al.   JOURNAL OF NEUROSCIENCE

A three-dimensional human neural cell culture model of Alzheimer’s disease

(2014) Se Hoon Choi et al.   NATURE

Gut Microbial Colonization Orchestrates TLR2 Expression, Signaling and Epithelial Proliferation in the Small Intestinal Mucosa

(2014) Nives Hörmann et al.   PLoS One

Commensal bacteria protect against food allergen sensitization

(2014) A. T. Stefka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aging-induced type I interferon response at the choroid plexus negatively affects brain function

(2014) K. Baruch et al.   SCIENCE

An intestinal commensal symbiosis factor controls neuroinflammation via TLR2-mediated CD39 signalling

(2014) Yan Wang et al.   Nature Communications

Effects of Multiple Genetic Loci on Age at Onset in Late-Onset Alzheimer Disease

(2014) Adam C. Naj et al.   JAMA Neurology

Type-1 interferon signaling mediates neuro-inflammatory events in models of Alzheimer's disease

(2013) Juliet M. Taylor et al.   NEUROBIOLOGY OF AGING

Alzheimer’s Disease Risk Gene CD33 Inhibits Microglial Uptake of Amyloid Beta

(2013) Ana Griciuc et al.   NEURON

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Inhibition of IL-12/IL-23 signaling reduces Alzheimer's disease–like pathology and cognitive decline

(2012) Johannes vom Berg et al.   NATURE MEDICINE

Variant of TREM2 Associated with the Risk of Alzheimer's Disease

(2012) Thorlakur Jonsson et al.   NEW ENGLAND JOURNAL OF MEDICINE

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Increased binding of peripheral benzodiazepine receptor in mild cognitive impairment–dementia converters measured by positron emission tomography with [11C]DAA1106

(2012) Fumihiko Yasuno et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea

(2011) Daniel McDonald et al.   ISME Journal

TLR4 mutation reduces microglial activation, increases Aβ deposits and exacerbates cognitive deficits in a mouse model of Alzheimer's disease

(2011) Min Song et al.   Journal of Neuroinflammation

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Peripheral education of the immune system by colonic commensal microbiota

(2011) Stephanie K. Lathrop et al.   NATURE

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

(2011) Adam C Naj et al.   NATURE GENETICS

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

FastTree 2 – Approximately Maximum-Likelihood Trees for Large Alignments

(2010) Morgan N. Price et al.   PLoS One

PyNAST: a flexible tool for aligning sequences to a template alignment

(2009) J. G. Caporaso et al.   BIOINFORMATICS

16S rRNA gene-based analysis of fecal microbiota from preterm infants with and without necrotizing enterocolitis

(2009) Yunwei Wang et al.   ISME Journal

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

(2009) Jean-Charles Lambert et al.   NATURE GENETICS

Dissection of Hippocampal Dentate Gyrus from Adult Mouse

(2009) Hideo Hagihara et al.   Jove-Journal of Visualized Experiments

Ontogeny of altered dendritic morphology in the rat prefrontal cortex, hippocampus, and nucleus accumbens following Cesarean delivery and birth anoxia

(2008) Ismael Juárez et al.   JOURNAL OF COMPARATIVE NEUROLOGY