Nrg1 Intracellular Signaling Is Neuroprotective upon Stroke

Ageing, Cellular Senescence and Neurodegenerative Disease

(2018) Marios Kritsilis et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Aging Triggers Cytoplasmic Depletion and Nuclear Translocation of the E3 Ligase Mahogunin: A Function for Ubiquitin in Neuronal Survival

(2017) Stefano Benvegnù et al.   MOLECULAR CELL

Differential Aging Analysis in Human Cerebral Cortex Identifies Variants in TMEM106B and GRN that Regulate Aging Phenotypes

(2017) Herve Rhinn et al.   Cell Systems

Neuroinflammation-Induced Downregulation of Hippocampacal Neuregulin 1-ErbB4 Signaling in the Parvalbumin Interneurons Might Contribute to Cognitive Impairment in a Mouse Model of Sepsis-Associated Encephalopathy

(2016) Rong Gao et al.   INFLAMMATION

Differential changes in Neuregulin-1 signaling in major brain regions in a lipopolysaccharide-induced neuroinflammation mouse model

(2016) ZHAI YANG et al.   Molecular Medicine Reports

Neuregulin-1 (Nrg1) signaling has a preventive role and is altered in the frontal cortex under the pathological conditions of Alzheimer's disease

(2016) Qiong Jiang et al.   Molecular Medicine Reports

The reemergence of long-term potentiation in aged Alzheimer’s disease mouse model

(2016) Seonghoo Huh et al.   Scientific Reports

Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer’s disease model

(2016) Jiqing Xu et al.   Scientific Reports

Long-term Neuroglial Cocultures as a Brain Aging Model: Hallmarks of Senescence, MicroRNA Expression Profiles, and Comparison With In Vivo Models

(2015) Elisabetta Bigagli et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44

(2015) Liseth M. Parra et al.   MOLECULAR AND CELLULAR BIOLOGY

Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents

(2014) M. G. Martin et al.   EMBO Molecular Medicine

Cell autonomous regulation of hippocampal circuitry via Aph1b-γ-secretase/neuregulin 1 signalling

(2014) Pietro Fazzari et al.   eLife

Intramembranous Valine Linked to Schizophrenia Is Required for Neuregulin 1 Regulation of the Morphological Development of Cortical Neurons

(2013) Y. Chen et al.   JOURNAL OF NEUROSCIENCE

Reversal of Behavioral Deficits and Synaptic Dysfunction in Mice Overexpressing Neuregulin 1

(2013) Dong-Min Yin et al.   NEURON

Erbb4 Deletion from Fast-Spiking Interneurons Causes Schizophrenia-like Phenotypes

(2013) Isabel del Pino et al.   NEURON

Differential Neuregulin 1 Cleavage in the Prefrontal Cortex and Hippocampus in Schizophrenia and Bipolar Disorder: Preliminary Findings

(2012) Ketan Marballi et al.   PLoS One

Neuregulin signaling, cortical circuitry development and schizophrenia

(2011) Beatriz Rico et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Specific Regulation of NRG1 Isoform Expression by Neuronal Activity

(2011) X. Liu et al.   JOURNAL OF NEUROSCIENCE

Biological Validation of Increased Schizophrenia Risk With NRG1, ERBB4, and AKT1 Epistasis via Functional Neuroimaging in Healthy Controls

(2010) Kristin K. Nicodemus et al.   ARCHIVES OF GENERAL PSYCHIATRY

The Influence of Schizophrenia-Related Neuregulin-1 Polymorphisms on Sensorimotor Gating in Healthy Males

(2010) Panos Roussos et al.   BIOLOGICAL PSYCHIATRY

In vivo and in vitro genetic evidence of involvement of neuregulin 1 in immune system dysregulation

(2010) Ketan Marballi et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Nrg1 Reverse Signaling in Cortical Pyramidal Neurons

(2010) S. P. Pedrique et al.   JOURNAL OF NEUROSCIENCE

Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling

(2010) Pietro Fazzari et al.   NATURE

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

ErbB4 in parvalbumin-positive interneurons is critical for neuregulin 1 regulation of long-term potentiation

(2010) Y.-J. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuregulin 1 regulates pyramidal neuron activity via ErbB4 in parvalbumin-positive interneurons

(2009) L. Wen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance

(2008) Athanasia Spandidos et al.   BMC GENOMICS

Neuregulin 1 in neural development, synaptic plasticity and schizophrenia

(2008) Lin Mei et al.   NATURE REVIEWS NEUROSCIENCE

Estrogen and aging affect synaptic distribution of phosphorylated LIM kinase (pLIMK) in CA1 region of female rat hippocampus

(2008) M. Yildirim et al.   NEUROSCIENCE

Deficiency of Aph1B/C- -secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment

(2008) T. Dejaegere et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA