Role of integrins in mediating cardiac fibroblast–cardiomyocyte cross talk: a dynamic relationship in cardiac biology and pathophysiology

The α11 integrin mediates fibroblast–extracellular matrix–cardiomyocyte interactions in health and disease

(2016) Robert A. Civitarese et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cells and extracellular matrix interplay in cardiac valve disease: because age matters

(2016) Cristiano Spadaccio et al.   BASIC RESEARCH IN CARDIOLOGY

Cross-talk between macrophages and atrial myocytes in atrial fibrillation

(2016) Zewei Sun et al.   BASIC RESEARCH IN CARDIOLOGY

From basic mechanisms to clinical applications in heart protection, new players in cardiovascular diseases and cardiac theranostics: meeting report from the third international symposium on “New frontiers in cardiovascular research”

(2016) Hector A. Cabrera-Fuentes et al.   BASIC RESEARCH IN CARDIOLOGY

Mesenchymal stem cells attenuate inflammatory processes in the heart and lung via inhibition of TNF signaling

(2016) Alessandra Martire et al.   BASIC RESEARCH IN CARDIOLOGY

The plasma membrane calcium ATPase 4 signalling in cardiac fibroblasts mediates cardiomyocyte hypertrophy

(2016) Tamer M. A. Mohamed et al.   Nature Communications

Revisiting Cardiac Cellular CompositionNovelty and Significance

(2015) Alexander R. Pinto et al.   CIRCULATION RESEARCH

Cardiac endothelium–myocyte interaction: clinical opportunities for new heart failure therapies regardless of ejection fraction

(2015) Shir Lynn Lim et al.   EUROPEAN HEART JOURNAL

The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship

(2015) Boris Hinz   MATRIX BIOLOGY

Targeting MMP-2 to treat ischemic heart injury

(2014) Bryan G. Hughes et al.   BASIC RESEARCH IN CARDIOLOGY

Brag2 differentially regulates β1- and β3-integrin-dependent adhesion in endothelial cells and is involved in developmental and pathological angiogenesis

(2014) Yosif Manavski et al.   BASIC RESEARCH IN CARDIOLOGY

Interleukin-6-dependent phenotypic modulation of cardiac fibroblasts after acute myocardial infarction

(2014) Julia Müller et al.   BASIC RESEARCH IN CARDIOLOGY

Inflammation revisited: inflammation versus resolution of inflammation following myocardial infarction

(2014) Vasundhara Kain et al.   BASIC RESEARCH IN CARDIOLOGY

The role of integrin α2 in cell and matrix therapy that improves perfusion, viability and function of infarcted myocardium

(2014) Ali Ahmadi et al.   BIOMATERIALS

Integrins and Integrin-Associated Proteins in the Cardiac Myocyte

(2014) Sharon Israeli-Rosenberg et al.   CIRCULATION RESEARCH

Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation

(2014) Franco Klingberg et al.   JOURNAL OF CELL BIOLOGY

Glycated Collagen Induces α11 Integrin Expression Through TGF-β2 and Smad3

(2014) Ilana Talior-Volodarsky et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Integrins in mechanotransduction

(2013) Tyler D Ross et al.   CURRENT OPINION IN CELL BIOLOGY

A dynamic spatiotemporal extracellular matrix facilitates epicardial-mediated vertebrate heart regeneration

(2013) Sarah E. Mercer et al.   DEVELOPMENTAL BIOLOGY

Dynamic cell–cell and cell–ECM interactions in the heart

(2013) Catherine M. Howard et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

A directional switch of integrin signalling and a new anti-thrombotic strategy

(2013) Bo Shen et al.   NATURE

Cardiac Fibroblast-Derived Extracellular Matrix (Biomatrix) as a Model for the Studies of Cardiac Primitive Cell Biological Properties in Normal and Pathological Adult Human Heart

(2013) Clotilde Castaldo et al.   Biomed Research International

β1 Integrin Gene Excision in the Adult Murine Cardiac Myocyte Causes Defective Mechanical and Signaling Responses

(2012) Ruixia Li et al.   AMERICAN JOURNAL OF PATHOLOGY

Trends in the incidence and outcomes of heart failure in Ontario, Canada: 1997 to 2007

(2012) D. F. Yeung et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

α11 integrin stimulates myofibroblast differentiation in diabetic cardiomyopathy

(2012) Ilana Talior-Volodarsky et al.   CARDIOVASCULAR RESEARCH

A Strong Regenerative Ability of Cardiac Stem Cells Derived From Neonatal Hearts

(2012) D. L. Simpson et al.   CIRCULATION

MicroRNA-Mediated In Vitro and In Vivo Direct Reprogramming of Cardiac Fibroblasts to Cardiomyocytes

(2012) Tilanthi M. Jayawardena et al.   CIRCULATION RESEARCH

Extracellular Matrix Promotes Highly Efficient Cardiac Differentiation of Human Pluripotent Stem Cells

(2012) Jianhua Zhang et al.   CIRCULATION RESEARCH

α11β1 integrin-mediated MMP-13-dependent collagen lattice contraction by fibroblasts: Evidence for integrin-coordinated collagen proteolysis

(2012) Malgorzata M. Barczyk et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Collagen XIV is important for growth and structural integrity of the myocardium

(2012) Ge Tao et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Heart repair by reprogramming non-myocytes with cardiac transcription factors

(2012) Kunhua Song et al.   NATURE

In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes

(2012) Li Qian et al.   NATURE

β3 Integrin in Cardiac Fibroblast Is Critical for Extracellular Matrix Accumulation during Pressure Overload Hypertrophy in Mouse

(2012) Sundaravadivel Balasubramanian et al.   PLoS One

Mechanical stress-activated integrin  5 1 induces opening of connexin 43 hemichannels

(2012) N. Batra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Biofabrication enables efficient interrogation and optimization of sequential culture of endothelial cells, fibroblasts and cardiomyocytes for formation of vascular cords in cardiac tissue engineering

(2012) Rohin K Iyer et al.   Biofabrication

Integrin Targeted Therapeutics

(2012) Melissa Millard et al.   Theranostics

Extracellular matrix and heart development

(2011) Marie Lockhart et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Integrin expression during reverse remodeling in the myocardium of heart failure patients

(2011) Hub F.J. Dullens et al.   CARDIOVASCULAR PATHOLOGY

Cardiac myocyte force development during differentiation and maturation

(2010) Jeffrey G. Jacot et al.   Annals of the New York Academy of Sciences

Direct Reprogramming of Fibroblasts into Functional Cardiomyocytes by Defined Factors

(2010) Masaki Ieda et al.   CELL

Intramyocardial Fibroblast Myocyte Communication

(2010) Rahul Kakkar et al.   CIRCULATION RESEARCH

Integrin–TGF-β crosstalk in fibrosis, cancer and wound healing

(2010) Coert Margadant et al.   EMBO REPORTS

The Fibroblast Integrin α11β1 Is Induced in a Mechanosensitive Manner Involving Activin A and Regulates Myofibroblast Differentiation

(2010) Sergio Carracedo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The final steps of integrin activation: the end game

(2010) Sanford J. Shattil et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrins and Extracellular Matrix in Mechanotransduction

(2010) M. A. Schwartz   Cold Spring Harbor Perspectives in Biology

Integrins

(2009) Malgorzata Barczyk et al.   CELL AND TISSUE RESEARCH

Functional Cardiomyocytes Derived From Human Induced Pluripotent Stem Cells

(2009) Jianhua Zhang et al.   CIRCULATION RESEARCH

The extracellular matrix in development and morphogenesis: A dynamic view

(2009) Tania Rozario et al.   DEVELOPMENTAL BIOLOGY

Cardiac Fibroblasts Regulate Myocardial Proliferation through β1 Integrin Signaling

(2009) Masaki Ieda et al.   DEVELOPMENTAL CELL

β3 Integrin-mediated ubiquitination activates survival signaling during myocardial hypertrophy

(2009) Rebecca K. Johnston et al.   FASEB JOURNAL

Mechanobiology of cardiomyocyte development

(2009) Jeffrey G. Jacot et al.   JOURNAL OF BIOMECHANICS

Protein O-Glycosylation Induces Collagen Expression and Contributes to Diabetic Cardiomyopathy in Rat Cardiac Fibroblasts

(2009) Yuka Kohda et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

The human α11 integrin promoter drives fibroblast-restricted expression in vivo and is regulated by TGF-β1 in a Smad- and Sp1-dependent manner

(2009) Ning Lu et al.   MATRIX BIOLOGY

Mechanically Activated Integrin Switch Controls  5 1 Function

(2009) J. C. Friedland et al.   SCIENCE

Diabetic Cardiomyopathy: Insights into Pathogenesis, Diagnostic Challenges, and Therapeutic Options

(2008) Ashish Aneja et al.   AMERICAN JOURNAL OF MEDICINE

Stem cell engineering for treatment of heart diseases: Potentials and challenges

(2008) Shengwen Calvin Li et al.   CELL BIOLOGY INTERNATIONAL

Connexin43 Expression Levels Influence Intercellular Coupling and Cell Proliferation of Native Murine Cardiac Fibroblasts

(2008) Yan Zhang et al.   CELL COMMUNICATION AND ADHESION

Integrins and the activation of latent transforming growth factor β1 – An intimate relationship

(2008) P WIPFF et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Matrix Metalloproteinase 2-Integrin αvβ3 Binding Is Required for Mesenchymal Cell Invasive Activity but Not Epithelial Locomotion: A Computational Time-Lapse Study

(2008) Paul A. Rupp et al.   MOLECULAR BIOLOGY OF THE CELL

Pre-treatment of synthetic elastomeric scaffolds by cardiac fibroblasts improves engineered heart tissue

(2007) Milica Radisic et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A