BMI1 is directly regulated by androgen receptor to promote castration-resistance in prostate cancer

BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1

(2018) Sen Zhu et al.   Nature Communications

TMPRSS2–ERG fusion co-opts master transcription factors and activates NOTCH signaling in primary prostate cancer

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Targeting glioma stem cells through combined BMI1 and EZH2 inhibition

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The novel BMI-1 inhibitor PTC596 downregulates MCL-1 and induces p53-independent mitochondrial apoptosis in acute myeloid leukemia progenitor cells

(2017) Y Nishida et al.   Blood Cancer Journal

UGT2B17 Expedites Progression of Castration-Resistant Prostate Cancers by Promoting Ligand-Independent AR Signaling

(2016) Haolong Li et al.   CANCER RESEARCH

BMI-1 Targeting Interferes with Patient-Derived Tumor-Initiating Cell Survival and Tumor Growth in Prostate Cancer

(2016) N. Bansal et al.   CLINICAL CANCER RESEARCH

Targeted BMI1 inhibition impairs tumor growth in lung adenocarcinomas with low CEBPα expression

(2016) Kol Jia Yong et al.   Science Translational Medicine

Bmi1 marks distinct castration-resistant luminal progenitor cells competent for prostate regeneration and tumour initiation

(2016) Young A. Yoo et al.   Nature Communications

ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor

(2016) Zineb Mounir et al.   eLife

TWIST1 and BMI1 in Cancer Metastasis and Chemoresistance

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The BMI1 polycomb protein represses cyclin G2-induced autophagy to support proliferation in chronic myeloid leukemia cells

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Progesterone receptor expression during prostate cancer progression suggests a role of this receptor in stromal cell differentiation

(2015) Yue Yu et al.   PROSTATE

CtBP2 Modulates the Androgen Receptor to Promote Prostate Cancer Progression

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Self-renewal as a therapeutic target in human colorectal cancer

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Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

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DANPOS: Dynamic analysis of nucleosome position and occupancy by sequencing

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The mutational landscape of lethal castration-resistant prostate cancer

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Role of BMI1, a Stem Cell Factor, in Cancer Recurrence and Chemoresistance: Preclinical and Clinical Evidences

(2012) Hifzur Rahman Siddique et al.   STEM CELLS

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

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FIMO: scanning for occurrences of a given motif

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Androgen deprivation causes EMT in the prostate

(2011) Melanie Clyne   Nature Reviews Urology

BigWig and BigBed: enabling browsing of large distributed datasets

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Integrative Genomic Profiling of Human Prostate Cancer

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Glucocorticoid receptor signaling and prostate cancer

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Small Cell Carcinoma of the Prostate

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The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells

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MicroRNA miR-34 Inhibits Human Pancreatic Cancer Tumor-Initiating Cells

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Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

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