Bmi1 marks distinct castration-resistant luminal progenitor cells competent for prostate regeneration and tumour initiation

Illuminating the Properties of Prostate Luminal Progenitors

(2015) Michael M. Shen   Cell Stem Cell

Stem Cell Antigen-1 Identifies a Distinct Androgen-Independent Murine Prostatic Luminal Cell Lineage with Bipotent Potential

(2015) Oh-Joon Kwon et al.   STEM CELLS

Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors

(2015) Supreet Agarwal et al.   Cell Reports

PIM Kinase Inhibitor AZD1208 for Treatment of MYC-Driven Prostate Cancer

(2014) Austin N. Kirschner et al.   JNCI-Journal of the National Cancer Institute

Single luminal epithelial progenitors can generate prostate organoids in culture

(2014) Chee Wai Chua et al.   NATURE CELL BIOLOGY

Symmetrical and asymmetrical division analysis provides evidence for a hierarchy of prostate epithelial cell lineages

(2014) Jia Wang et al.   Nature Communications

Luminal Cells Are Favored as the Cell of Origin for Prostate Cancer

(2014) Zhu A. Wang et al.   Cell Reports

Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity

(2013) Zhu A. Wang et al.   NATURE CELL BIOLOGY

Prostate cancer originating in basal cells progresses to adenocarcinoma propagated by luminal-like cells

(2013) T. Stoyanova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Adult Murine Prostate Basal and Luminal Cells Are Self-Sustained Lineages that Can Both Serve as Targets for Prostate Cancer Initiation

(2012) Nahyun Choi et al.   CANCER CELL

Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis

(2012) Philip D. Anderson et al.   JOURNAL OF CLINICAL INVESTIGATION

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer

(2012) Karim Nacerddine et al.   JOURNAL OF CLINICAL INVESTIGATION

Multipotent and unipotent progenitors contribute to prostate postnatal development

(2012) Marielle Ousset et al.   NATURE CELL BIOLOGY

Intestinal Crypt Homeostasis Results from Neutral Competition between Symmetrically Dividing Lgr5 Stem Cells

(2010) Hugo J. Snippert et al.   CELL

Bmi-1 Is a Crucial Regulator of Prostate Stem Cell Self-Renewal and Malignant Transformation

(2010) Rita U. Lukacs et al.   Cell Stem Cell

Identification of a Cell of Origin for Human Prostate Cancer

(2010) A. S. Goldstein et al.   SCIENCE

A luminal epithelial stem cell that is a cell of origin for prostate cancer

(2009) Xi Wang et al.   NATURE

Generation of a prostate from a single adult stem cell

(2008) Kevin G. Leong et al.   NATURE

Bmi1 is expressed in vivo in intestinal stem cells

(2008) Eugenio Sangiorgi et al.   NATURE GENETICS

Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics

(2008) A. S. Goldstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA