Targeted BMI1 inhibition impairs tumor growth in lung adenocarcinomas with low CEBPα expression

Drug Index

(2014)   Journal of Thoracic Oncology

Targeting self-renewal, an Achilles' heel of cancer stem cells

(2014) Max S Wicha   NATURE MEDICINE

Sox4 Is a Key Oncogenic Target in C/EBPα Mutant Acute Myeloid Leukemia

(2013) Hong Zhang et al.   CANCER CELL

A 12-Gene Set Predicts Survival Benefits from Adjuvant Chemotherapy in Non-Small Cell Lung Cancer Patients

(2013) H. Tang et al.   CLINICAL CANCER RESEARCH

C/EBPa controls acquisition and maintenance of adult haematopoietic stem cell quiescence

(2013) Min Ye et al.   NATURE CELL BIOLOGY

Self-renewal as a therapeutic target in human colorectal cancer

(2013) Antonija Kreso et al.   NATURE MEDICINE

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

shRNA-mediated knockdown of Bmi-1 inhibit lung adenocarcinoma cell migration and metastasis

(2012) Xiuxiang Meng et al.   LUNG CANCER

BMI1 as a novel target for drug discovery in cancer

(2011) Liangxian Cao et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

C/EBPα Expression Is Downregulated in Human Nonmelanoma Skin Cancers and Inactivation of C/EBPα Confers Susceptibility to UVB-Induced Skin Squamous Cell Carcinomas

(2011) Elizabeth A. Thompson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Prognostic and Predictive Gene Signature for Adjuvant Chemotherapy in Resected Non–Small-Cell Lung Cancer

(2010) Chang-Qi Zhu et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting post-transcriptional control for drug discovery

(2010) Stuart W. Peltz et al.   RNA Biology

BMI-1 Promotes Ewing Sarcoma Tumorigenicity Independent of CDKN2A Repression

(2008) D. Douglas et al.   CANCER RESEARCH

Stem cell marker expression in small cell lung carcinoma and developing lung tissue

(2008) Lin-Kristin Koch et al.   HUMAN PATHOLOGY

Prognostic value of Bmi-1 oncoprotein expression in NSCLC patients: a tissue microarray study

(2008) Katerina Vrzalikova et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Dysregulation of the C/EBPα Differentiation Pathway in Human Cancer

(2008) Steffen Koschmieder et al.   JOURNAL OF CLINICAL ONCOLOGY

Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion

(2008) J. S. Dovey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of Bmi-1 in Epidermis Enhances Cell Survival by Altering Cell Cycle Regulatory Protein Expression and Inhibiting Apoptosis

(2007) Kathy Lee et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY