Association of Oseltamivir Activation with Gender and Carboxylesterase 1 Genetic Polymorphisms

Targeted absolute quantitative proteomics with SILAC internal standards and unlabeled full-length protein calibrators (TAQSI)

(2016) Xinwen Wang et al.   RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril

(2015) E. Katriina Tarkiainen et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans

(2015) EK Tarkiainen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials

(2015) Joanna Dobson et al.   LANCET

Individualization of treatments with drugs metabolized by CES1: combining genetics and metabolomics

(2015) Henrik Berg Rasmussen et al.   PHARMACOGENOMICS

CES1 genetic variation affects the activation of angiotensin-converting enzyme inhibitors

(2015) X Wang et al.   PHARMACOGENOMICS JOURNAL

The effects of CES1A2 A(−816)C and CYP2C19 loss-of-function polymorphisms on clopidogrel response variability among Chinese patients with coronary heart disease

(2014) Cheng Xie et al.   Pharmacogenetics and Genomics

Oseltamivir for influenza in adults and children: systematic review of clinical study reports and summary of regulatory comments

(2014) T. Jefferson et al.   BMJ-British Medical Journal

Genetic Determinants of Dabigatran Plasma Levels and Their Relation to Bleeding

(2013) Guillaume Paré et al.   CIRCULATION

CES1A −816C as a Genetic Marker to Predict Greater Platelet Clopidogrel Response in Patients with Percutaneous Coronary Intervention

(2013) Jian-Jun Zou et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

The Role of Human Carboxylesterases in Drug Metabolism: Have We Overlooked Their Importance?

(2013) S. Casey Laizure et al.   PHARMACOTHERAPY

Examination of the carboxylesterase phenotype in human liver

(2012) Matthew K. Ross et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Carboxylesterase 1 Polymorphism Impairs Oseltamivir Bioactivation in Humans

(2012) E K Tarkiainen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

(2012) Joshua P. Lewis et al.   Pharmacogenetics and Genomics

Pharmacokinetics of Oseltamivir and Oseltamivir Carboxylate in Critically Ill Patients Receiving Continuous Venovenous Hemodialysis and/or Extracorporeal Membrane Oxygenation

(2012) Rachel F. Eyler et al.   PHARMACOTHERAPY

Surge in Expression of Carboxylesterase 1 During the Post-neonatal Stage Enables a Rapid Gain of the Capacity to Activate the Anti-influenza Prodrug Oseltamivir

(2011) Deshi Shi et al.   JOURNAL OF INFECTIOUS DISEASES

Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril

(2009) Hao-Jie Zhu et al.   BIOCHEMICAL PHARMACOLOGY

Studies on the influence of esterase inhibitor to the pharmacokinetic profiles of oseltamivir and oseltamivir carboxylate in rats using an improved LC/MS/MS method

(2009) Qi Chang et al.   BIOMEDICAL CHROMATOGRAPHY

Age- and Sex-Related Expression and Activity of Carboxylesterase 1 and 2 in Mouse and Human Liver

(2009) H.-J. Zhu et al.   DRUG METABOLISM AND DISPOSITION

A Possible Mechanism for the Differences in Efficiency and Variability of Active Metabolite Formation from Thienopyridine Antiplatelet Agents, Prasugrel and Clopidogrel

(2009) K. Hagihara et al.   DRUG METABOLISM AND DISPOSITION

Carboxylesterase 1 gene polymorphism and methylphenidate response in ADHD

(2009) Zsofia Nemoda et al.   NEUROPHARMACOLOGY

Two CES1 Gene Mutations Lead to Dysfunctional Carboxylesterase 1 Activity in Man: Clinical Significance and Molecular Basis

(2008) Hao-Jie Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Pharmacokinetics of High-Dose Oseltamivir in Healthy Volunteers

(2008) Y. Wattanagoon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Functional polymorphisms in carboxylesterase1A2 (CES1A2) gene involves specific protein 1 (Sp1) binding sites

(2008) Mika Yoshimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Human carboxylesterases HCE1 and HCE2: Ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin

(2008) Dongfang Yang et al.   BIOCHEMICAL PHARMACOLOGY

Clinical Pharmacokinetics and Pharmacodynamics of the Oral Direct Thrombin??Inhibitor Dabigatran Etexilate

(2008) Joachim Stangier   CLINICAL PHARMACOKINETICS

Activation of the Antiviral Prodrug Oseltamivir Is Impaired by Two Newly Identified Carboxylesterase 1 Variants

(2008) H.-J. Zhu et al.   DRUG METABOLISM AND DISPOSITION

Sex-specific differences in CYP450 isoforms in humans

(2008) Marissa J Scandlyn et al.   Expert Opinion on Drug Metabolism & Toxicology

Structure and characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes

(2008) Tatsuki Fukami et al.   Pharmacogenetics and Genomics