Effect of carboxylesterase 1 c.428G > A single nucleotide variation on the pharmacokinetics of quinapril and enalapril

Carboxylesterase 1 c.428G>A single nucleotide variation increases the antiplatelet effects of clopidogrel by reducing its hydrolysis in humans

(2015) EK Tarkiainen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Clopidogrel Bioactivation and Risk of Bleeding in Patients Cotreated With Angiotensin-Converting Enzyme Inhibitors After Myocardial Infarction: A Proof-of-Concept Study

(2014) K E Kristensen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Evaluation of the Inhibitory Effects of Antihypertensive Drugs on Human Carboxylesterase In Vitro

(2013) Xu Yanjiao et al.   Drug Metabolism and Pharmacokinetics

Carboxylesterase 1 Polymorphism Impairs Oseltamivir Bioactivation in Humans

(2012) E K Tarkiainen et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

The functional G143E variant of carboxylesterase 1 is associated with increased clopidogrel active metabolite levels and greater clopidogrel response

(2012) Joshua P. Lewis et al.   Pharmacogenetics and Genomics

Effect of Organic Anion-Transporting Polypeptide 1B1 (OATP1B1) Polymorphism on the Single- and Multiple-Dose Pharmacokinetics of Enalapril in Healthy Chinese Adult Men

(2011) Lei Tian et al.   CLINICAL THERAPEUTICS

Organic Anion Transporting Polypeptide 1B1: a Genetically Polymorphic Transporter of Major Importance for Hepatic Drug Uptake

(2011) M. Niemi et al.   PHARMACOLOGICAL REVIEWS

In Vitro Evaluation of Inhibitory Effects of Antidiabetic and Antihyperlipidemic Drugs on Human Carboxylesterase Activities

(2010) T. Fukami et al.   DRUG METABOLISM AND DISPOSITION

Carboxylesterase 1 (Ces1): from monocyte marker to major player

(2010) G. M. Markey   JOURNAL OF CLINICAL PATHOLOGY

Common genetic variations of the renin–angiotensin–aldosterone system and response to acute angiotensin I-converting enzyme inhibition in essential hypertension

(2010) Tuula Hannila-Handelberg et al.   JOURNAL OF HYPERTENSION

Role of carboxylesterase 1 and impact of natural genetic variants on the hydrolysis of trandolapril

(2009) Hao-Jie Zhu et al.   BIOCHEMICAL PHARMACOLOGY

Carboxylesterase 1 gene polymorphism and methylphenidate response in ADHD

(2009) Zsofia Nemoda et al.   NEUROPHARMACOLOGY

Two CES1 Gene Mutations Lead to Dysfunctional Carboxylesterase 1 Activity in Man: Clinical Significance and Molecular Basis

(2008) Hao-Jie Zhu et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Activation of the Antiviral Prodrug Oseltamivir Is Impaired by Two Newly Identified Carboxylesterase 1 Variants

(2008) H.-J. Zhu et al.   DRUG METABOLISM AND DISPOSITION