Chronic inflammation and cancer: suppressing the suppressors

Tumor Necrosis Factor-α Blocks Differentiation and Enhances Suppressive Activity of Immature Myeloid Cells during Chronic Inflammation

(2013) Moshe Sade-Feldman et al.   IMMUNITY

Vemurafenib reverses immunosuppression by myeloid derived suppressor cells

(2013) Bastian Schilling et al.   INTERNATIONAL JOURNAL OF CANCER

Premetastatic soil and prevention of breast cancer brain metastasis

(2013) Y. Liu et al.   NEURO-ONCOLOGY

Clinical Perspectives on Targeting of Myeloid Derived Suppressor Cells in the Treatment of Cancer

(2013) Yana G. Najjar et al.   Frontiers in Oncology

Myeloid suppressor cells and immune modulation in lung cancer

(2012) Minu K Srivastava et al.   Immunotherapy

Anti-tumor necrosis factor and postoperative complications in Crohnʼs disease: systematic review and meta-analysis

(2012) Uri Kopylov et al.   INFLAMMATORY BOWEL DISEASES

TNF signaling drives myeloid-derived suppressor cell accumulation

(2012) Xueqiang Zhao et al.   JOURNAL OF CLINICAL INVESTIGATION

Increased Myeloid-Derived Suppressor Cells in Gastric Cancer Correlate with Cancer Stage and Plasma S100A8/A9 Proinflammatory Proteins

(2012) L. Wang et al.   JOURNAL OF IMMUNOLOGY

Blockade of Myeloid-Derived Suppressor Cells after Induction of Lymphopenia Improves Adoptive T Cell Therapy in a Murine Model of Melanoma

(2012) K. N. Kodumudi et al.   JOURNAL OF IMMUNOLOGY

Paclitaxel promotes differentiation of myeloid-derived suppressor cells into dendritic cellsin vitroin a TLR4-independent manner

(2012) Tillmann Michels et al.   Journal of Immunotoxicology

Cyclophosphamide Promotes Chronic Inflammation–Dependent Immunosuppression and Prevents Antitumor Response in Melanoma

(2012) Alexandra Sevko et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Anti-Gr-1 antibody depletion fails to eliminate hepatic myeloid-derived suppressor cells in tumor-bearing mice

(2012) Chi Ma et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Combined vaccine+axitinib therapy yields superior antitumor efficacy in a murine melanoma model

(2012) Anamika Bose et al.   MELANOMA RESEARCH

Chemotherapy-triggered cathepsin B release in myeloid-derived suppressor cells activates the Nlrp3 inflammasome and promotes tumor growth

(2012) Mélanie Bruchard et al.   NATURE MEDICINE

Myeloid Suppressor Cell Depletion Augments Antitumor Activity in Lung Cancer

(2012) Minu K. Srivastava et al.   PLoS One

New insights into chronic inflammation-induced immunosuppression

(2012) Julia Kanterman et al.   SEMINARS IN CANCER BIOLOGY

Chemoimmunomodulation of MDSCs as a novel strategy for cancer therapy

(2012) Julie Djeu et al.   OncoImmunology

Tumor necrosis factor therapy and the risk of serious infection and malignancy in patients with early rheumatoid arthritis: A meta-analysis of randomized controlled trials

(2011) Andrew E. Thompson et al.   ARTHRITIS AND RHEUMATISM

Restoration of Antitumor Immunity Through Selective Inhibition of Myeloid Derived Suppressor Cells by Anticancer Therapies

(2011) L. Apetoh et al.   CURRENT MOLECULAR MEDICINE

Role of myeloid-derived suppressor cells in tumor immunotherapy

(2011) François Martin et al.   Immunotherapy

Icariin and its derivative, ICT, exert anti-inflammatory, anti-tumor effects, and modulate myeloid derived suppressive cells (MDSCs) functions

(2011) Junmin Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chronic inflammation promotes myeloid-derived suppressor cell activation blocking antitumor immunity in transgenic mouse melanoma model

(2011) C. Meyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Icariin Derivative Inhibits Inflammation through Suppression of p38 Mitogen-Activated Protein Kinase and Nuclear Factor-κB Pathways

(2010) Shao-Rui Chen et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function

(2010) Joris D Veltman et al.   BMC CANCER

5-Fluorouracil Selectively Kills Tumor-Associated Myeloid-Derived Suppressor Cells Resulting in Enhanced T Cell-Dependent Antitumor Immunity

(2010) J. Vincent et al.   CANCER RESEARCH

A Novel Chemoimmunomodulating Property of Docetaxel: Suppression of Myeloid-Derived Suppressor Cells in Tumor Bearers

(2010) K. N. Kodumudi et al.   CLINICAL CANCER RESEARCH

The biology of myeloid-derived suppressor cells: The blessing and the curse of morphological and functional heterogeneity

(2010) Je-In Youn et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Myeloid derived suppressor cells and their role in tolerance induction in cancer

(2010) Taku Fujimura et al.   JOURNAL OF DERMATOLOGICAL SCIENCE

Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients

(2009) J. S. Ko et al.   CLINICAL CANCER RESEARCH

Inflammation enhances myeloid-derived suppressor cell cross-talk by signaling through Toll-like receptor 4

(2009) Stephanie K. Bunt et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis

(2008) Li Yang et al.   CANCER CELL

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

(2008) C. Marcela Diaz-Montero et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Sunitinib-Induced Myeloid Lineage Redistribution in Renal Cell Cancer Patients: CD1c+ Dendritic Cell Frequency Predicts Progression-Free Survival

(2008) H. van Cruijsen et al.   CLINICAL CANCER RESEARCH

Tumor-induced tolerance and immune suppression by myeloid derived suppressor cells

(2008) Ilaria Marigo et al.   IMMUNOLOGICAL REVIEWS

The anticancer immune response: indispensable for therapeutic success?

(2008) Laurence Zitvogel et al.   JOURNAL OF CLINICAL INVESTIGATION