Toll-like receptor mediated inflammation requires FASN-dependent MYD88 palmitoylation

Evidence that TLR4 Is Not a Receptor for Saturated Fatty Acids but Mediates Lipid-Induced Inflammation by Reprogramming Macrophage Metabolism

(2018) Graeme I. Lancaster et al.   Cell Metabolism

An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation

(2018) Richard G. Carroll et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fatty acid synthesis configures the plasma membrane for inflammation in diabetes

(2016) Xiaochao Wei et al.   NATURE

Aurkb/PP1-mediated resetting of Oct4 during the cell cycle determines the identity of embryonic stem cells

(2016) Jihoon Shin et al.   eLife

GPS-Lipid: a robust tool for the prediction of multiple lipid modification sites

(2016) Yubin Xie et al.   Scientific Reports

Role of lipid microdomains in TLR-mediated signalling

(2015) Jean-Marie Ruysschaert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

(2015) Jong-Seok Moon et al.   JOURNAL OF CLINICAL INVESTIGATION

Sepsis: a roadmap for future research

(2015) Jonathan Cohen et al.   LANCET INFECTIOUS DISEASES

Diversity and selectivity in mRNA translation on the endoplasmic reticulum

(2015) David W. Reid et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nr0b1 is a negative regulator of Zscan4c in mouse embryonic stem cells

(2015) Setsuko Fujii et al.   Scientific Reports

The Science of Fatty Acids and Inflammation

(2015) Kevin L Fritsche   Advances in Nutrition

Clickable Analogue of Cerulenin as Chemical Probe to Explore Protein Palmitoylation

(2014) Baohui Zheng et al.   ACS Chemical Biology

In-depth analysis of site-specific N-glycosylation in vitronectin from human plasma by tandem mass spectrometry with immunoprecipitation

(2014) Heeyoun Hwang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

De novo fatty acid synthesis controls the fate between regulatory T and T helper 17 cells

(2014) Luciana Berod et al.   NATURE MEDICINE

Stable expression and function of the inositol 1,4,5-triphosphate receptor requires palmitoylation by a DHHC6/selenoprotein K complex

(2014) Gregory J. Fredericks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular Fatty Acid Metabolism and Cancer

(2013) Erin Currie et al.   Cell Metabolism

Fatty Acid Synthase Modulates Intestinal Barrier Function through Palmitoylation of Mucin 2

(2012) Xiaochao Wei et al.   Cell Host & Microbe

Palmitoylated calnexin is a key component of the ribosome-translocon complex

(2012) Asvin KK Lakkaraju et al.   EMBO JOURNAL

Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways

(2012) Shurong Huang et al.   JOURNAL OF LIPID RESEARCH

Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system

(2012) Yusuke Ohno et al.   MOLECULAR BIOLOGY OF THE CELL

Endoplasmic Reticulum Localization of DHHC Palmitoyltransferases Mediated by Lysine-based Sorting Signals

(2011) Oforiwa A. Gorleku et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Role of Intermediary Domain of MyD88 in Cell Activation and Therapeutic Inhibition of TLRs

(2011) M. Avbelj et al.   JOURNAL OF IMMUNOLOGY

The neutrophil in vascular inflammation

(2011) Mia Phillipson et al.   NATURE MEDICINE

De NovoLipogenesis Maintains Vascular Homeostasis through Endothelial Nitric-oxide Synthase (eNOS) Palmitoylation

(2010) Xiaochao Wei et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The intracellular dynamic of protein palmitoylation

(2010) Christine Salaun et al.   JOURNAL OF CELL BIOLOGY

Macrophage ABCA1 reduces MyD88-dependent Toll-like receptor trafficking to lipid rafts by reduction of lipid raft cholesterol

(2010) Xuewei Zhu et al.   JOURNAL OF LIPID RESEARCH

Quantitative Proteome and Transcriptome Analysis of the ArchaeonThermoplasma acidophilumCultured under Aerobic and Anaerobic Conditions

(2010) Na Sun et al.   JOURNAL OF PROTEOME RESEARCH

Small-molecule inhibition of APT1 affects Ras localization and signaling

(2010) Frank J Dekker et al.   Nature Chemical Biology

Protein palmitoylation in neuronal development and synaptic plasticity

(2010) Yuko Fukata et al.   NATURE REVIEWS NEUROSCIENCE

Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome

(2009) Michael B Fessler et al.   CURRENT OPINION IN LIPIDOLOGY

Identification of Critical Residues of the MyD88 Death Domain Involved in the Recruitment of Downstream Kinases

(2009) Maria Loiarro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Rapid and selective detection of fatty acylated proteins using ω-alkynyl-fatty acids and click chemistry

(2009) Megan C. Yap et al.   JOURNAL OF LIPID RESEARCH

Palmitoylation of Nicotinic Acetylcholine Receptors

(2009) J. K. Alexander et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Robust Fluorescent Detection of Protein Fatty-Acylation with Chemical Reporters

(2009) Guillaume Charron et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Immunodesign of experimental sepsis by cecal ligation and puncture

(2009) Daniel Rittirsch et al.   Nature Protocols

Overexpression of fatty acid synthase is associated with palmitoylation of Wnt1 and cytoplasmic stabilization of β-catenin in prostate cancer

(2008) Michelangelo Fiorentino et al.   LABORATORY INVESTIGATION