Immuno-SABER enables highly multiplexed and amplified protein imaging in tissues

SABER amplifies FISH: enhanced multiplexed imaging of RNA and DNA in cells and tissues

(2019) Jocelyn Y. Kishi et al.   NATURE METHODS

Third-generationin situhybridization chain reaction: multiplexed, quantitative, sensitive, versatile, robust

(2018) Harry M. T. Choi et al.   DEVELOPMENT

X10 expansion microscopy enables 25‐nm resolution on conventional microscopes

(2018) Sven Truckenbrodt et al.   EMBO REPORTS

A hybridization-chain-reaction-based method for amplifying immunosignals

(2018) Rui Lin et al.   NATURE METHODS

Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes

(2018) Jia-Ren Lin et al.   eLife

Automated cell-type classification in intact tissues by single-cell molecular profiling

(2018) Monica Nagendran et al.   eLife

DNA-Sequence-Encoded Rolling Circle Amplicon for Single-Cell RNA Imaging

(2018) Ruijie Deng et al.   Chem

Deep Profiling of Mouse Splenic Architecture with CODEX Multiplexed Imaging

(2018) Yury Goltsev et al.   CELL

Mapping 3D genome organization relative to nuclear compartments using TSA-Seq as a cytological ruler

(2018) Yu Chen et al.   JOURNAL OF CELL BIOLOGY

Multiplexed protein maps link subcellular organization to cellular states

(2018) Gabriele Gut et al.   SCIENCE

Rapid Sequential in Situ Multiplexing with DNA Exchange Imaging in Neuronal Cells and Tissues

(2017) Yu Wang et al.   NANO LETTERS

Super-multiplex vibrational imaging

(2017) Lu Wei et al.   NATURE

Programmable autonomous synthesis of single-stranded DNA

(2017) Jocelyn Y. Kishi et al.   Nature Chemistry

Iterative expansion microscopy

(2017) Jae-Byum Chang et al.   NATURE METHODS

Simultaneous epitope and transcriptome measurement in single cells

(2017) Marlon Stoeckius et al.   NATURE METHODS

The Human Cell Atlas

(2017) Aviv Regev et al.   eLife

Multiplexed and scalable super-resolution imaging of three-dimensional protein localization in size-adjustable tissues

(2016) Taeyun Ku et al.   NATURE BIOTECHNOLOGY

Nanoscale imaging of RNA with expansion microscopy

(2016) Fei Chen et al.   NATURE METHODS

High-throughput single-cell gene-expression profiling with multiplexed error-robust fluorescence in situ hybridization

(2016) Jeffrey R. Moffitt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiplexed tissue biomarker imaging

(2016) Edward C. Stack et al.   Journal for ImmunoTherapy of Cancer

Immunohistochemistry and mass spectrometry for highly multiplexed cellular molecular imaging

(2015) Richard M Levenson et al.   LABORATORY INVESTIGATION

The pros and cons of vertebrate animal models for functional and therapeutic research on inherited retinal dystrophies

(2015) Ralph W.N. Slijkerman et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Expansion microscopy

(2015) F. Chen et al.   SCIENCE

Tissue-based map of the human proteome

(2015) M. Uhlen et al.   SCIENCE

Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method

(2015) Jia-Ren Lin et al.   Nature Communications

Machine-based method for multiplex in situ molecular characterization of tissues by immunofluorescence detection

(2015) Dmitry Yarilin et al.   Scientific Reports

Multiplexed ion beam imaging of human breast tumors

(2014) Michael Angelo et al.   NATURE MEDICINE

Multiplexed 3D cellular super-resolution imaging with DNA-PAINT and Exchange-PAINT

(2014) Ralf Jungmann et al.   NATURE METHODS

Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

(2014) Charlotte Giesen et al.   NATURE METHODS

Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue

(2013) M. J. Gerdes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

OMERO: flexible, model-driven data management for experimental biology

(2012) Chris Allan et al.   NATURE METHODS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

The quantitative proteome of a human cell line

(2011) M. Beck et al.   Molecular Systems Biology

Tyramide signal amplification for analysis of kinase activity by intracellular flow cytometry

(2010) Matthew R. Clutter et al.   CYTOMETRY PART A

NUPACK: Analysis and design of nucleic acid systems

(2010) Joseph N. Zadeh et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Defining the transcriptome and proteome in three functionally different human cell lines

(2010) Emma Lundberg et al.   Molecular Systems Biology

Programmable in situ amplification for multiplexed imaging of mRNA expression

(2010) Harry M T Choi et al.   NATURE BIOTECHNOLOGY

Superresolution Imaging of Chemical Synapses in the Brain

(2010) Adish Dani et al.   NEURON