Multiplexed protein maps link subcellular organization to cellular states

The Human Cell Atlas: from vision to reality

(2017) Orit Rozenblatt-Rosen et al.   NATURE

Applying systems-level spectral imaging and analysis to reveal the organelle interactome

(2017) Alex M. Valm et al.   NATURE

A subcellular map of the human proteome

(2017) Peter J. Thul et al.   SCIENCE

Comparison of clustering methods for high-dimensional single-cell flow and mass cytometry data

(2016) Lukas M. Weber et al.   CYTOMETRY PART A

Highly multiplexed simultaneous detection of RNAs and proteins in single cells

(2016) Andreas P Frei et al.   NATURE METHODS

Control of Transcript Variability in Single Mammalian Cells

(2015) Nico Battich et al.   CELL

Data-Driven Phenotypic Dissection of AML Reveals Progenitor-like Cells that Correlate with Prognosis

(2015) Jacob H. Levine et al.   CELL

FlowSOM: Using self-organizing maps for visualization and interpretation of cytometry data

(2015) Sofie Van Gassen et al.   CYTOMETRY PART A

Cell-intrinsic adaptation of lipid composition to local crowding drives social behaviour

(2015) Mathieu Frechin et al.   NATURE

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

(2015) Francesca Zanconato et al.   NATURE CELL BIOLOGY

Trajectories of cell-cycle progression from fixed cell populations

(2015) Gabriele Gut et al.   NATURE METHODS

Spatially resolved, highly multiplexed RNA profiling in single cells

(2015) K. H. Chen et al.   SCIENCE

Quantitative analysis reveals how EGFR activation and downregulation are coupled in normal but not in cancer cells

(2015) Fabrizio Capuani et al.   Nature Communications

Highly multiplexed imaging of single cells using a high-throughput cyclic immunofluorescence method

(2015) Jia-Ren Lin et al.   Nature Communications

A Hierarchical Map of Regulatory Genetic Interactions in Membrane Trafficking

(2014) Prisca Liberali et al.   CELL

Elution of High-affinity (>10-9 KD) Antibodies from Tissue Sections

(2014) Rossella Gendusa et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Multiplexed immunohistochemistry, imaging, and quantitation: A review, with an assessment of Tyramide signal amplification, multispectral imaging and multiplex analysis

(2014) Edward C. Stack et al.   METHODS

Multiplexed ion beam imaging of human breast tumors

(2014) Michael Angelo et al.   NATURE MEDICINE

Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry

(2014) Charlotte Giesen et al.   NATURE METHODS

In the right place at the right time: visualizing and understanding mRNA localization

(2014) Adina R. Buxbaum et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Highly Multiplexed Subcellular RNA Sequencing in Situ

(2014) J. H. Lee et al.   SCIENCE

Threshold-controlled ubiquitination of the EGFR directs receptor fate

(2013) Sara Sigismund et al.   EMBO JOURNAL

Automated Detection and Quantification of Granular Cell Compartments

(2013) Hicham Mahboubi et al.   MICROSCOPY AND MICROANALYSIS

Image-based transcriptomics in thousands of single human cells at single-molecule resolution

(2013) Nico Battich et al.   NATURE METHODS

Quantitative single-cell RNA-seq with unique molecular identifiers

(2013) Saiful Islam et al.   NATURE METHODS

Highly multiplexed single-cell analysis of formalin-fixed, paraffin-embedded cancer tissue

(2013) M. J. Gerdes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantum dot imaging platform for single-cell molecular profiling

(2013) Pavel Zrazhevskiy et al.   Nature Communications

Multiplexed In Situ Immunofluorescence Using Dynamic DNA Complexes

(2012) Ryan M. Schweller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single-cell analysis of population context advances RNAi screening at multiple levels

(2012) Berend Snijder et al.   Molecular Systems Biology

CEL-Seq: Single-Cell RNA-Seq by Multiplexed Linear Amplification

(2012) Tamar Hashimshony et al.   Cell Reports

Lysosomal positioning coordinates cellular nutrient responses

(2011) Viktor I. Korolchuk et al.   NATURE CELL BIOLOGY

Next-generation biomarkers based on 100-parameter functional super-resolution microscopy TIS

(2011) Walter Schubert et al.   New Biotechnology

Nanoscale distribution of mitochondrial import receptor Tom20 is adjusted to cellular conditions and exhibits an inner-cellular gradient

(2011) C. A. Wurm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CellClassifier: supervised learning of cellular phenotypes

(2009) Pauli Rämö et al.   BIOINFORMATICS

Population context determines cell-to-cell variability in endocytosis and virus infection

(2009) Berend Snijder et al.   NATURE

Efficient subpixel image registration algorithms

(2008) Manuel Guizar-Sicairos et al.   OPTICS LETTERS