Association between major depressive disorder and multiple disease outcomes: a phenome-wide Mendelian randomisation study in the UK Biobank

Selection bias when estimating average treatment effects using one-sample instrumental variable analysis

(2019) Rachael A. Hughes et al.   EPIDEMIOLOGY

A simulation study investigating power estimates in phenome-wide association studies

(2018) Anurag Verma et al.   BMC BIOINFORMATICS

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

(2018) Naomi R. Wray et al.   NATURE GENETICS

Detection of widespread horizontal pleiotropy in causal relationships inferred from Mendelian randomization between complex traits and diseases

(2018) Marie Verbanck et al.   NATURE GENETICS

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Evaluating phecodes, clinical classification software, and ICD-9-CM codes for phenome-wide association studies in the electronic health record

(2017) Wei-Qi Wei et al.   PLoS One

Phenome-Wide Association Studies as a Tool to Advance Precision Medicine

(2016) Joshua C. Denny et al.   Annual Review of Genomics and Human Genetics

The serotonergic system in the neurobiology of depression: Relevance for novel antidepressants

(2016) Stephan Köhler et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Meta-analysis of genome-wide association studies of anxiety disorders

(2016) T Otowa et al.   MOLECULAR PSYCHIATRY

Identification of 15 genetic loci associated with risk of major depression in individuals of European descent

(2016) Craig L Hyde et al.   NATURE GENETICS

The new NHGRI-EBI Catalog of published genome-wide association studies (GWAS Catalog)

(2016) Jacqueline MacArthur et al.   NUCLEIC ACIDS RESEARCH

The Safety, Tolerability and Risks Associated with the Use of Newer Generation Antidepressant Drugs: A Critical Review of the Literature

(2016) André F. Carvalho et al.   PSYCHOTHERAPY AND PSYCHOSOMATICS

Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA

(2016) Johannes Kettunen et al.   Nature Communications

Cohort profile of the UK Biobank: diagnosis and characteristics of cerebrovascular disease

(2016) J Hewitt et al.   BMJ Open

Use of Selective Serotonin Reuptake Inhibitors and Risk of Upper Gastrointestinal Bleeding: A Systematic Review and Meta-analysis

(2015) Hai-Yin Jiang et al.   Clinical Gastroenterology and Hepatology

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

The Economic Burden of Adults With Major Depressive Disorder in the United States (2005 and 2010)

(2015) Paul E. Greenberg et al.   JOURNAL OF CLINICAL PSYCHIATRY

A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease

(2015) Majid Nikpay et al.   NATURE GENETICS

The Relationship between Depression and Asthma: A Meta-Analysis of Prospective Studies

(2015) Yong-hua Gao et al.   PLoS One

MR-PheWAS: hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization

(2015) Louise A. C. Millard et al.   Scientific Reports

Drug-disease and drug-drug interactions: systematic examination of recommendations in 12 UK national clinical guidelines

(2015) S. Dumbreck et al.   BMJ-British Medical Journal

Drug-disease and drug-drug interactions: systematic examination of recommendations in 12 UK national clinical guidelines

(2015) S. Dumbreck et al.   BMJ-British Medical Journal

R PheWAS: data analysis and plotting tools for phenome-wide association studies in the R environment

(2014) Robert J. Carroll et al.   BIOINFORMATICS

Depression and the risk of coronary heart disease: a meta-analysis of prospective cohort studies

(2014) Yong Gan et al.   BMC Psychiatry

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data

(2013) Joshua C Denny et al.   NATURE BIOTECHNOLOGY

Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease

(2012) Brian A. Ference et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY