MR-PheWAS: hypothesis prioritization among potential causal effects of body mass index on many outcomes, using Mendelian randomization

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis

(2014) Michael V. Holmes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Methodological Challenges in Mendelian Randomization

(2014) Tyler J. VanderWeele et al.   EPIDEMIOLOGY

Mendelian randomization of blood lipids for coronary heart disease

(2014) Michael V. Holmes et al.   EUROPEAN HEART JOURNAL

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

(2014) G. Davey Smith et al.   HUMAN MOLECULAR GENETICS

Obesity impairs academic attainment in adolescence: findings from ALSPAC, a UK cohort

(2014) J N Booth et al.   INTERNATIONAL JOURNAL OF OBESITY

How to Make More Published Research True

(2014) John P. A. Ioannidis   PLOS MEDICINE

Metabolic Signatures of Adiposity in Young Adults: Mendelian Randomization Analysis and Effects of Weight Change

(2014) Peter Würtz et al.   PLOS MEDICINE

Causal relationship between body mass index and fetuin-A level in the asian population: a bidirectional mendelian randomization study

(2013) Ammarin Thakkinstian et al.   CLINICAL ENDOCRINOLOGY

Use of allele scores as instrumental variables for Mendelian randomization

(2013) Stephen Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts

(2013) T. M. Palmer et al.   BMJ-British Medical Journal

Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates

(2013) David M. Evans et al.   PLoS Genetics

The Role of Adiposity in Cardiometabolic Traits: A Mendelian Randomization Analysis

(2013) Tove Fall et al.   PLOS MEDICINE

Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts

(2013) Karani S. Vimaleswaran et al.   PLOS MEDICINE

Data-driven integration of epidemiological and toxicological data to select candidate interacting genes and environmental factors in association with disease

(2012) C. J. Patel et al.   BIOINFORMATICS

A Nutrient-Wide Association Study on Blood Pressure

(2012) Ioanna Tzoulaki et al.   CIRCULATION

Systematic evaluation of environmental factors: persistent pollutants and nutrients correlated with serum lipid levels

(2012) Chirag J Patel et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort

(2012) A. Fraser et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Cohort Profile: The ‘Children of the 90s’—the index offspring of the Avon Longitudinal Study of Parents and Children

(2012) Andy Boyd et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Serum Uric Acid and Adiposity: Deciphering Causality Using a Bidirectional Mendelian Randomization Approach

(2012) Tanica Lyngdoh et al.   PLoS One

The Effect of Elevated Body Mass Index on Ischemic Heart Disease Risk: Causal Estimates from a Mendelian Randomisation Approach

(2012) Børge G. Nordestgaard et al.   PLOS MEDICINE

Random Allocation in Observational Data

(2011) George Davey Smith   EPIDEMIOLOGY

The FTO gene polymorphism is associated with end-stage renal disease: two large independent case-control studies in a general population

(2011) J. A. Hubacek et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Using multiple genetic variants as instrumental variables for modifiable risk factors

(2011) Tom M Palmer et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Association between Common Variation at the FTO Locus and Changes in Body Mass Index from Infancy to Late Childhood: The Complex Nature of Genetic Association through Growth and Development

(2011) Ulla Sovio et al.   PLoS Genetics

Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health

(2010) George Davey Smith   Genes and Nutrition

C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization

(2010) N J Timpson et al.   INTERNATIONAL JOURNAL OF OBESITY

Socioeconomic disparities in trajectories of adiposity across childhood

(2010) Laura D. Howe et al.   International Journal of Pediatric Obesity

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Multiple imputation using chained equations: Issues and guidance for practice

(2010) Ian R. White et al.   STATISTICS IN MEDICINE

Socioeconomic position and overweight among adolescents: data from birth cohort studies in Brazil and the UK

(2009) Alicia Matijasevich et al.   BMC PUBLIC HEALTH

Does Greater Adiposity Increase Blood Pressure and Hypertension Risk?

(2009) Nicholas J. Timpson et al.   HYPERTENSION

Obesity and cancer: Mendelian randomization approach utilizing the FTO genotype

(2009) P. Brennan et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Infancy Weight Gain Predicts Childhood Body Fat and Age at Menarche in Girls

(2009) Ken K. Ong et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach

(2009) Paul Welsh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common Variation in the FTO Gene Alters Diabetes-Related Metabolic Traits to the Extent Expected Given Its Effect on BMI

(2008) R. M. Freathy et al.   DIABETES

Why Most Discovered True Associations Are Inflated

(2008) John P. A. Ioannidis   EPIDEMIOLOGY

Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using Mendelian randomization in the Cardiovascular Risk in Young Finns study

(2008) M. Kivimaki et al.   EUROPEAN HEART JOURNAL

How Does Body Fat Influence Bone Mass in Childhood? A Mendelian Randomization Approach

(2008) Nicholas J Timpson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Genome-wide association studies for complex traits: consensus, uncertainty and challenges

(2008) Mark I. McCarthy et al.   NATURE REVIEWS GENETICS

Associations between birth weight, early childhood weight gain and adult lung function

(2008) R J Hancox et al.   THORAX

Mendelian randomization: Using genes as instruments for making causal inferences in epidemiology

(2007) Debbie A. Lawlor et al.   STATISTICS IN MEDICINE