Reactive Gliosis Contributes to Nrf2-Dependent Neuroprotection by Pretreatment with Dimethyl Fumarate or Korean Red Ginseng Against Hypoxic-Ischemia: Focus on Hippocampal Injury

Korean Red Ginseng Pretreatment Protects Against Long-Term Sensorimotor Deficits After Ischemic Stroke Likely Through Nrf2

(2018) Lei Liu et al.   Frontiers in Cellular Neuroscience

Pretreatment with Korean red ginseng or dimethyl fumarate attenuates reactive gliosis and confers sustained neuroprotection against cerebral hypoxic-ischemic damage by an Nrf2-dependent mechanism

(2018) Lei Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Reactive astrogliosis in stroke: Contributions of astrocytes to recovery of neurological function

(2017) Neil R. Sims et al.   NEUROCHEMISTRY INTERNATIONAL

Postconditioning-induced neuroprotection, mechanisms and applications in cerebral ischemia

(2017) Yan-Ying Fan et al.   NEUROCHEMISTRY INTERNATIONAL

Preconditioning in neuroprotection: From hypoxia to ischemia

(2017) Sijie Li et al.   PROGRESS IN NEUROBIOLOGY

Translational Stroke Research

(2017) Francesca Bosetti et al.   STROKE

Comparing eight types of ginsenosides in ginseng of different plant ages and regions using RRLC-Q-TOF MS/MS

(2017) Yu-Lin Dai et al.   Journal of Ginseng Research

Transcriptional Regulation by Nrf2

(2017) Claudia Tonelli et al.   ANTIOXIDANTS & REDOX SIGNALING

Pharmacodynamics of Dimethyl Fumarate Are Tissue Specific and Involve NRF2-Dependent and -Independent Mechanisms

(2016) Melanie S. Brennan et al.   ANTIOXIDANTS & REDOX SIGNALING

Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's Disease

(2016) Isabel Lastres-Becker et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive gliosis in the pathogenesis of CNS diseases

(2016) Milos Pekny et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The role of microglia and macrophages in glioma maintenance and progression

(2016) Dolores Hambardzumyan et al.   NATURE NEUROSCIENCE

Ischaemic conditioning and reperfusion injury

(2016) Derek J. Hausenloy et al.   Nature Reviews Cardiology

Dimethyl Fumarate and Monomethyl Fumarate Promote Post-Ischemic Recovery in Mice

(2016) Yang Yao et al.   Translational Stroke Research

Heart Disease and Stroke Statistics—2016 Update

(2015) Dariush Mozaffarian et al.   CIRCULATION

Dimethyl fumarate attenuates cerebral edema formation by protecting the blood–brain barrier integrity

(2015) Reiner Kunze et al.   EXPERIMENTAL NEUROLOGY

Astrocyte barriers to neurotoxic inflammation

(2015) Michael V. Sofroniew   NATURE REVIEWS NEUROSCIENCE

Critical Evaluation of the Changes in Glutamine Synthetase Activity in Models of Cerebral Stroke

(2015) Thomas M. Jeitner et al.   NEUROCHEMICAL RESEARCH

Dimethyl Fumarate Protects Brain From Damage Produced by Intracerebral Hemorrhage by Mechanism Involving Nrf2

(2015) Xiurong Zhao et al.   STROKE

Astrocyte Overexpression of Heme Oxygenase-1 Improves Outcome After Intracerebral Hemorrhage

(2015) J. Chen-Roetling et al.   STROKE

Comparison of human Nrf2 antibodies: A tale of two proteins

(2015) Zachary A. Kemmerer et al.   TOXICOLOGY LETTERS

Ginseng: a promising neuroprotective strategy in stroke

(2015) Vaibhav Rastogi et al.   Frontiers in Cellular Neuroscience

The central role of aquaporins in the pathophysiology of ischemic stroke

(2015) Jasmine Vella   Frontiers in Cellular Neuroscience

The HIF-1/glial TIM-3 axis controls inflammation-associated brain damage under hypoxia

(2015) Han Seok Koh et al.   Nature Communications

Characterization of Korean Red Ginseng (Panax ginseng Meyer): History, preparation method, and chemical composition

(2015) Sang Myung Lee et al.   Journal of Ginseng Research

Dimethyl Fumarate and Monoethyl Fumarate Exhibit Differential Effects on KEAP1, NRF2 Activation, and Glutathione Depletion In Vitro

(2015) Melanie S. Brennan et al.   PLoS One

Dimethyl fumarate for treating relapsing multiple sclerosis

(2014) William Sheremata et al.   Expert Opinion On Drug Safety

Aquaporins: important but elusive drug targets

(2014) Alan S. Verkman et al.   NATURE REVIEWS DRUG DISCOVERY

Reactive Gliosis and the Multicellular Response to CNS Damage and Disease

(2014) Joshua E. Burda et al.   NEURON

Role of Nrf2 in Oxidative Stress and Toxicity

(2013) Qiang Ma   Annual Review of Pharmacology and Toxicology

Prostaglandin F2α FP receptor antagonist improves outcomes after experimental traumatic brain injury

(2013) Alexander V Glushakov et al.   Journal of Neuroinflammation

Reciprocal Modulation Between Microglia and Astrocyte in Reactive Gliosis Following the CNS Injury

(2013) Zhongwen Gao et al.   MOLECULAR NEUROBIOLOGY

Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases

(2013) Hemant Kumar et al.   NATURAL PRODUCT REPORTS

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Physiological Roles of Aquaporin-4 in Brain

(2013) Erlend A. Nagelhus et al.   PHYSIOLOGICAL REVIEWS

Transient Receptor Potential Canonical 3 Inhibitor Pyr3 Improves Outcomes and Attenuates Astrogliosis After Intracerebral Hemorrhage in Mice

(2013) Masaya Munakata et al.   STROKE

Effects of Korean Red Ginseng extract on tissue plasminogen activator and plasminogen activator inhibitor-1 expression in cultured rat primary astrocytes

(2013) Hyun Myung Ko et al.   Journal of Ginseng Research

The Predicted Molecular Weight of Nrf2: It Is What It Is Not

(2012) Alexandria Lau et al.   ANTIOXIDANTS & REDOX SIGNALING

CXCR4 Antagonist AMD3100 Protects Blood–Brain Barrier Integrity and Reduces Inflammatory Response After Focal Ischemia in Mice

(2012) Jun Huang et al.   STROKE

Korean red ginseng protects against neuronal damage induced by transient focal ischemia in rats

(2012) JU YEON BAN et al.   Experimental and Therapeutic Medicine

Therapeutic Effect of Korean Red Ginseng on Inflammatory Cytokines in Rats with Focal Cerebral Ischemia/Reperfusion Injury

(2011) Jong Seok Lee et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Conserved aquaporin 4 levels associated with reduction of brain edema are mediated by estrogen in the ischemic brain after experimental stroke

(2011) Jin A. Shin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dietary flavonoids are neuroprotective through Nrf2-coordinated induction of endogenous cytoprotective proteins

(2011) Christopher C. Leonardo et al.   NUTRITIONAL NEUROSCIENCE

Carbon Monoxide–Activated Nrf2 Pathway Leads to Protection Against Permanent Focal Cerebral Ischemia

(2011) Bing Wang et al.   STROKE

The Science of Stroke: Mechanisms in Search of Treatments

(2010) Michael A. Moskowitz et al.   NEURON

The Nrf2–ARE cytoprotective pathway in astrocytes

(2009) Marcelo R. Vargas et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use

(2009) Ulrich Dirnagl et al.   LANCET NEUROLOGY

Neuroprotection and Enhancement of Spatial Memory by Herbal Mixture HT008-1 in Rat Global Brain Ischemia Model

(2008) Yun Tai Kim et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

The Nrf2/ARE Pathway as a Potential Therapeutic Target in Neurodegenerative Disease

(2008) Marcus J. Calkins et al.   ANTIOXIDANTS & REDOX SIGNALING

Neuroprotection and repair

(2007) J. Palace   JOURNAL OF THE NEUROLOGICAL SCIENCES