Histone deacetylase inhibitors restore IL-10 expression in lipopolysaccharide-induced cell inflammation and reduce IL-1β and IL-6 production in breast silicone implant in C57BL/6J wild-type murine model

Selective Inhibitors of Zinc-Dependent Histone Deacetylases. Therapeutic Targets Relevant to Cancer

(2015) Jakub Kollar et al.   CURRENT PHARMACEUTICAL DESIGN

Novel Histone Deacetylase Inhibitors Induce Growth Arrest, Apoptosis, and Differentiation in Sarcoma Cancer Stem Cells

(2015) Gemma Di Pompo et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mast Cells in the Periprosthetic Breast Capsule

(2014) Jacqueline Brazin et al.   AESTHETIC PLASTIC SURGERY

Specific Inhibition of Histone Deacetylase 8 Reduces Gene Expression and Production of Proinflammatory Cytokinesin Vitroandin Vivo

(2014) Suzhao Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Design and Optimization of Novel Hydroxamate-Based Histone Deacetylase Inhibitors of Bis-Substituted Aromatic Amides Bearing Potent Activities against Tumor Growth and Metastasis

(2014) Feifei Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

The promise and perils of HDAC inhibitors in neurodegeneration

(2014) Alessandro Didonna et al.   Annals of Clinical and Translational Neurology

tert-Butylcarbamate-Containing Histone Deacetylase Inhibitors: Apoptosis Induction, Cytodifferentiation, and Antiproliferative Activities in Cancer Cells

(2013) Sergio Valente et al.   ChemMedChem

Immunomodulatory Effects of Histone Deacetylase Inhibitors

(2013) P.V. Licciardi et al.   CURRENT MOLECULAR MEDICINE

Mediatory role of interleukin-6 in α smooth muscle actin induction and myofibroblast formation around silicone tissue expander

(2013) Josna Joseph et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Histone deacetylase isoforms regulate innate immune responses by deacetylating mitogen-activated protein kinase phosphatase-1

(2013) Y. Jeong et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Epigenetic regulation of inflammation: progressing from broad acting histone deacetylase (HDAC) inhibitors to targeting specific HDACs

(2013) Melissa D. Cantley et al.   INFLAMMOPHARMACOLOGY

Lipopolysaccharide Inhibits Th2 Lung Inflammation Induced by House Dust Mite Allergens in Mice

(2012) J. Daan de Boer et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Histone/protein deacetylases and T-cell immune responses

(2012) T. Akimova et al.   BLOOD

Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages

(2012) X. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Histone deacetylase inhibitors suppress rheumatoid arthritis fibroblast-like synoviocyte and macrophage IL-6 production by accelerating mRNA decay

(2011) Aleksander M Grabiec et al.   ANNALS OF THE RHEUMATIC DISEASES

Histone deacetylases are dysregulated in rheumatoid arthritis and a novel histone deacetylase 3-selective inhibitor reduces interleukin-6 production by peripheral blood mononuclear cells from rheumatoid arthritis patients

(2011) Justin Gillespie et al.   ARTHRITIS AND RHEUMATISM

Novel Cinnamyl Hydroxyamides and 2-Aminoanilides as Histone Deacetylase Inhibitors: Apoptotic Induction and Cytodifferentiation Activity

(2011) Sergio Valente et al.   ChemMedChem

Combined Treatment of Etanercept and MTX Reverses Th1/Th2, Th17/Treg Imbalance in Patients with Rheumatoid Arthritis

(2011) Chen Lina et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Histone Deacetylase 6 and Heat Shock Protein 90 Control the Functions of Foxp3+ T-Regulatory Cells

(2011) E. F. de Zoeten et al.   MOLECULAR AND CELLULAR BIOLOGY

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(2011) Leo Joosten et al.   MOLECULAR MEDICINE

Anti-inflammatory Agents: Present and Future

(2010) Charles A. Dinarello   CELL

Synthesis and Biological Characterization of Amidopropenyl Hydroxamates as HDAC Inhibitors

(2010) Florian Thaler et al.   ChemMedChem

Histone/protein deacetylase inhibitors increase suppressive functions of human FOXP3+ Tregs

(2010) Tatiana Akimova et al.   CLINICAL IMMUNOLOGY

Histone Deacetylase Inhibitors Suppress Inflammatory Activation of Rheumatoid Arthritis Patient Synovial Macrophages and Tissue

(2010) Aleksander M. Grabiec et al.   JOURNAL OF IMMUNOLOGY

Histone Deacetylase: A Potential Therapeutic Target for Fibrotic Disorders

(2010) M. Pang et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Breast augmentation: Part II – adverse capsular contracture

(2010) M.G. Berry et al.   Journal of Plastic Reconstructive and Aesthetic Surgery

Rational Design and Simple Chemistry Yield a Superior, Neuroprotective HDAC6 Inhibitor, Tubastatin A

(2010) Kyle V. Butler et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes

(2010) Matt J. Barter et al.   MATRIX BIOLOGY

HDAC inhibitors and neurodegeneration: At the edge between protection and damage

(2010) Karen C. Dietz et al.   PHARMACOLOGICAL RESEARCH

Fibroblasts Express Immune Relevant Genes and Are Important Sentinel Cells during Tissue Damage in Rainbow Trout (Oncorhynchus mykiss)

(2010) Hans-Christian Ingerslev et al.   PLoS One

Effects of Singulair (Montelukast) Treatment for Capsular Contracture

(2010) Catherine K. Huang et al.   Aesthetic Surgery Journal

Anti-inflammatory effect of Trichostatin-A on murine bone marrow-derived macrophages

(2009) Sang-Bae Han et al.   ARCHIVES OF PHARMACAL RESEARCH

IL-1β and IL-2 convert human Treg into TH17 cells

(2009) Florence Deknuydt et al.   CLINICAL IMMUNOLOGY

Histone Deacetylase Inhibitors and Neurodegenerative Disorders: Holding the Promise

(2009) Antonello Mai et al.   CURRENT PHARMACEUTICAL DESIGN

Deacetylase inhibition increases regulatory T cell function and decreases incidence and severity of collagen-induced arthritis

(2009) Sandra J. Saouaf et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation

(2009) Craig L. Maynard et al.   IMMUNOLOGICAL REVIEWS

Synthesis and Biological Evaluation ofN-Hydroxyphenylacrylamides andN-Hydroxypyridin-2-ylacrylamides as Novel Histone Deacetylase Inhibitors

(2009) Florian Thaler et al.   JOURNAL OF MEDICINAL CHEMISTRY

Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

(2009) C. Choudhary et al.   SCIENCE

PROTECTIVE EFFECT OF SUBEROYLANILIDE HYDROXAMIC ACID AGAINST LPS-INDUCED SEPTIC SHOCK IN RODENTS

(2009) Yongqing Li et al.   SHOCK

Acetylation of mitogen-activated protein kinase phosphatase-1 inhibits Toll-like receptor signaling

(2008) Wangsen Cao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The histone deacetylase HDAC11 regulates the expression of interleukin 10 and immune tolerance

(2008) Alejandro Villagra et al.   NATURE IMMUNOLOGY

Trichostatin A, a histone deacetylase inhibitor, suppresses synovial inflammation and subsequent cartilage destruction in a collagen antibody-induced arthritis mouse model

(2008) Y. Nasu et al.   OSTEOARTHRITIS AND CARTILAGE