Bioactive Peptides Produced by Cyanobacteria of the Genus Nostoc: A Review

Cyanobacterial peptides beyond microcystins – A review on co-occurrence, toxicity, and challenges for risk assessment

(2019) Elisabeth M.-L. Janssen   WATER RESEARCH

Unlocking the Spatial Control of Secondary Metabolism Uncovers Hidden Natural Product Diversity in Nostoc punctiforme

(2019) Daniel Dehm et al.   ACS Chemical Biology

Synthesis and Biological Evaluation of RGD–Cryptophycin Conjugates for Targeted Drug Delivery

(2019) Adina Borbély et al.   Pharmaceutics

Therapeutic peptides: Historical perspectives, current development trends, and future directions

(2018) Jolene L. Lau et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Cyanopeptolins with Trypsin and Chymotrypsin Inhibitory Activity from the Cyanobacterium Nostoc edaphicum CCNP1411

(2018) Hanna Mazur-Marzec et al.   Marine Drugs

Mechanistic Probes for the Epimerization Domain of Nonribosomal Peptide Synthetases

(2018) Woojoo Kim et al.   CHEMBIOCHEM

Namalides B and C and Spumigins K–N from the Cultured Freshwater Cyanobacterium Sphaerospermopsis torques-reginae

(2017) Miriam Sanz et al.   JOURNAL OF NATURAL PRODUCTS

Cryptophycins: cytotoxic cyclodepsipeptides with potential for tumor targeting

(2017) Christine Weiss et al.   JOURNAL OF PEPTIDE SCIENCE

Structural Diversity, Biological Properties and Applications of Natural Products from Cyanobacteria. A Review

(2017) Sayed Shah et al.   Marine Drugs

Healthy efficacy of Nostoc commune Vaucher

(2017) Zhuoyu Li et al.   Oncotarget

Production of High Amounts of Hepatotoxin Nodularin and New Protease Inhibitors Pseudospumigins by the Brazilian Benthic Nostoc sp. CENA543

(2017) Jouni Jokela et al.   Frontiers in Microbiology

Cytomorphological and nitrogen metabolic enzyme analysis of psychrophilic and mesophilic Nostoc sp.: a comparative outlook

(2017) Bhuvaneshwari Thangaraj et al.   3 Biotech

Cytomorphological and nitrogen metabolic enzyme analysis of psychrophilic and mesophilic Nostoc sp.: a comparative outlook

(2017) Bhuvaneshwari Thangaraj et al.   3 Biotech

Discovery of anabaenopeptin 679 from freshwater algal bloom material: Insights into the structure–activity relationship of anabaenopeptin protease inhibitors

(2016) Henrik Harms et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Medusamide A, a Panamanian Cyanobacterial Depsipeptide with Multiple β-Amino Acids

(2016) Amanda M. Fenner et al.   ORGANIC LETTERS

Urumamide, a novel chymotrypsin inhibitor with a β-amino acid from a marine cyanobacterium Okeania sp.

(2016) Yuki Kanamori et al.   TETRAHEDRON LETTERS

The cryptophycins as potent payloads for antibody drug conjugates

(2015) Vishal A. Verma et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

Natural Product Biosynthetic Diversity and Comparative Genomics of the Cyanobacteria

(2015) Elke Dittmann et al.   TRENDS IN MICROBIOLOGY

Robust Vaginal Colonization of Macaques with a Novel Vaginally Disintegrating Tablet Containing a Live Biotherapeutic Product to Prevent HIV Infection in Women

(2015) Laurel A. Lagenaur et al.   PLoS One

4-Methylproline Guided Natural Product Discovery: Co-Occurrence of 4-Hydroxy- and 4-Methylprolines in Nostoweipeptins and Nostopeptolides

(2014) Liwei Liu et al.   ACS Chemical Biology

Ecophysiology of gelatinous Nostoc colonies: unprecedented slow growth and survival in resource-poor and harsh environments

(2014) Kaj Sand-Jensen   ANNALS OF BOTANY

Nostosins, Trypsin Inhibitors Isolated from the Terrestrial Cyanobacterium Nostoc sp. Strain FSN

(2014) Liwei Liu et al.   JOURNAL OF NATURAL PRODUCTS

Linker-Extended Native Cyanovirin-N Facilitates PEGylation and Potently Inhibits HIV-1 by Targeting the Glycan Ligand

(2014) Jia Chen et al.   PLoS One

Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes

(2014) H. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Fate of Microcystins in the Environment and Challenges for Monitoring

(2014) Justine Schmidt et al.   Toxins

Novel Aeruginosin-865 fromNostocsp. as a Potent Anti-inflammatory Agent

(2013) Aleksandra Kapuścik et al.   CHEMBIOCHEM

The Genetic Basis for O-Acetylation of the Microcystin Toxin in Cyanobacteria

(2013) David P. Fewer et al.   CHEMISTRY & BIOLOGY

Recent approaches for the synthesis of modified cryptophycins

(2013) Christine Weiss et al.   NATURAL PRODUCT REPORTS

Identification and toxigenic potential of a Nostoc sp.

(2013) Bahareh Nowruzi et al.   ALGAE

A gene expression study on strains of Nostoc (Cyanobacteria) revealing antimicrobial activity under mixotrophic conditions

(2012) B. Nowruzi   AFRICAN JOURNAL OF BIOTECHNOLOGY

Genetic diversity of symbiotic cyanobacteria in Cycas revoluta (Cycadaceae)

(2012) Shuntaro Yamada et al.   FEMS MICROBIOLOGY ECOLOGY

Nodularin, a cyanobacterial toxin, is synthesized in planta by symbiotic Nostoc sp.

(2012) Michelle M Gehringer et al.   ISME Journal

Cyanobacteria produce a high variety of hepatotoxic peptides in lichen symbiosis

(2012) U. Kaasalainen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nostophycin Biosynthesis Is Directed by a Hybrid Polyketide Synthase-Nonribosomal Peptide Synthetase in the Toxic Cyanobacterium Nostoc sp. Strain 152

(2011) David P. Fewer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Discovery and Synthesis of Namalide Reveals a New Anabaenopeptin Scaffold and Peptidase Inhibitor

(2011) Pradeep Cheruku et al.   JOURNAL OF MEDICINAL CHEMISTRY

THE TOXIC CYANOBACTERIUM NOSTOC SP. STRAIN 152 PRODUCES HIGHEST AMOUNTS OF MICROCYSTIN AND NOSTOPHYCIN UNDER STRESS CONDITIONS1

(2011) Rainer Kurmayer   JOURNAL OF PHYCOLOGY

Metabolism and resources of spherical colonies ofNostoc zetterstedtii

(2011) Kaj Sand-Jensen et al.   LIMNOLOGY AND OCEANOGRAPHY

Nostocyclopeptide-M1: A Potent, Nontoxic Inhibitor of the Hepatocyte Drug Transporters OATP1B3 and OATP1B1

(2011) Lars Herfindal et al.   MOLECULAR PHARMACEUTICS

Prevention of vaginal SHIV transmission in macaques by a live recombinant Lactobacillus

(2011) L A Lagenaur et al.   Mucosal Immunology

Cyanobactins—ribosomal cyclic peptides produced by cyanobacteria

(2010) Kaarina Sivonen et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A Novel Cyanobacterial Nostocyclopeptide is a Potent Antitoxin against Microcystins

(2010) Jouni Jokela  et al.   CHEMBIOCHEM

Two Alternative Starter Modules for the Non-Ribosomal Biosynthesis of Specific Anabaenopeptin Variants in Anabaena (Cyanobacteria)

(2010) Leo Rouhiainen et al.   CHEMISTRY & BIOLOGY

Consumption offa cai Nostocsoup: A Potential for BMAA exposure fromNostoccyanobacteria in China?

(2009) Britton R. Roney et al.   Amyotrophic Lateral Sclerosis

Soluble cytoplasmic expression, rapid purification, and characterization of cyanovirin-N as a His-SUMO fusion

(2009) Xianglei Gao et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Design, expression, and characterization of a multivalent, combination HIV microbicide

(2009) Amy Sexton et al.   FASEB JOURNAL

A Chinese rhesus macaque (Macaca mulatta) model for vaginalLactobacilluscolonization and live microbicide development

(2009) Rosa R. Yu et al.   JOURNAL OF MEDICAL PRIMATOLOGY

The non-ribosomal assembly and frequent occurrence of the protease inhibitors spumigins in the bloom-forming cyanobacteriumNodularia spumigena

(2009) David P. Fewer et al.   MOLECULAR MICROBIOLOGY

The Entropy Balance of Nostocyclopeptide Macrocyclization Analysed by NMR Spectroscopy

(2008) Sebastian Enck et al.   CHEMBIOCHEM

New Peptolides from the CyanobacteriumNostoc insulareas Selective and Potent Inhibitors of Human Leukocyte Elastase

(2008) Christian Mehner et al.   CHEMBIOCHEM

Secondary Metabolites from Cyanobacteria: Complex Structures and Powerful Bioactivities

(2008) Karl Gademann et al.   CURRENT ORGANIC CHEMISTRY

Cyanobacteria (Nostoc commune) used as a dietary item in the Peruvian highlands produce the neurotoxic amino acid BMAA

(2008) Holly E. Johnson et al.   JOURNAL OF ETHNOPHARMACOLOGY

PEGylation of cyanovirin–N, an entry inhibitor of HIV

(2007) H. Zappe et al.   ADVANCED DRUG DELIVERY REVIEWS