HIV-1 Tat-Induced Astrocytic Extracellular Vesicle miR-7 Impairs Synaptic Architecture

Exosomal miR-9 Released from HIV Tat Stimulated Astrocytes Mediates Microglial Migration

(2018) Lu Yang et al.   Journal of Neuroimmune Pharmacology

TNFα and IL-1β modify the miRNA cargo of astrocyte shed extracellular vesicles to regulate neurotrophic signaling in neurons

(2018) Amrita Datta Chaudhuri et al.   Cell Death & Disease

Antiretroviral Drugs Alter the Content of Extracellular Vesicles from HIV-1-Infected Cells

(2018) Catherine DeMarino et al.   Scientific Reports

Astrocyte EV-induced lincRNA-Cox2 regulates microglial phagocytosis: Implications for morphine-mediated potentiation of neurodegeneration

(2018) Guoku Hu et al.   Molecular Therapy-Nucleic Acids

The neurobiological bases of autism spectrum disorders: the R451C-neuroligin 3 mutation hampers the expression of long-term synaptic depression in the dorsal striatum

(2017) Giuseppina Martella et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Tat-Mediated Induction of miRs-34a & -138 Promotes Astrocytic Activation via Downregulation of SIRT1: Implications for Aging in HAND

(2017) Guoku Hu et al.   Journal of Neuroimmune Pharmacology

Cocaine-Mediated Downregulation of miR-124 Activates Microglia by Targeting KLF4 and TLR4 Signaling

(2017) Palsamy Periyasamy et al.   MOLECULAR NEUROBIOLOGY

Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis

(2017) Jeff A. Stogsdill et al.   NATURE

Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development

(2017) Jun Li et al.   NEURON

Molecular Mechanism of MDGA1: Regulation of Neuroligin 2:Neurexin Trans-synaptic Bridges

(2017) Shanti Pal Gangwar et al.   NEURON

Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions

(2017) Alex M. Dickens et al.   Science Signaling

HIV-1 Nef is released in extracellular vesicles derived from astrocytes: evidence for Nef-mediated neurotoxicity

(2017) A Sami Saribas et al.   Cell Death & Disease

Functional significance of rare neuroligin 1 variants found in autism

(2017) Moe Nakanishi et al.   PLoS Genetics

NPTX2 and cognitive dysfunction in Alzheimer’s Disease

(2017) Mei-Fang Xiao et al.   eLife

Dynamic Control of Synaptic Adhesion and Organizing Molecules in Synaptic Plasticity

(2017) Gabby Rudenko   NEURAL PLASTICITY

Astrocyte-shed extracellular vesicles regulate the peripheral leukocyte response to inflammatory brain lesions

(2017) Alex M. Dickens et al.   Science Signaling

Monocyte exosomes induce adhesion molecules and cytokines via activation of NF-κB in endothelial cells

(2016) Norina Tang et al.   FASEB JOURNAL

Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy

(2016) Yu Cai et al.   JOURNAL OF CELL BIOLOGY

HIV-1 Tat-shortened neurite outgrowth through regulation of microRNA-132 and its target gene expression

(2016) Pejman Rahimian et al.   Journal of Neuroinflammation

Neuroligin-2 and the tightrope of excitation/inhibition balance in the prefrontal cortex

(2016) Alice M. S. Durieux et al.   JOURNAL OF NEUROPHYSIOLOGY

Traumatic brain injury increases levels of miR-21 in extracellular vesicles: implications for neuroinflammation

(2016) Emily B. Harrison et al.   FEBS Open Bio

Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses

(2015) Bo Zhang et al.   NEURON

Micro RNA in Exosomes from HIV-Infected Macrophages

(2015) William Roth et al.   International Journal of Environmental Research and Public Health

Post-transcriptional regulation of SHANK3 expression by microRNAs related to multiple neuropsychiatric disorders

(2015) Su-Yeon Choi et al.   Molecular Brain

MiR-21 in Extracellular Vesicles Leads to Neurotoxicity via TLR7 Signaling in SIV Neurological Disease

(2015) Sowmya V. Yelamanchili et al.   PLoS Pathogens

Association of Cytokines With Exosomes in the Plasma of HIV-1–Seropositive Individuals

(2014) Kateena Addae Konadu et al.   JOURNAL OF INFECTIOUS DISEASES

Exosomes as mediators of neuroinflammation

(2014) Archana Gupta et al.   Journal of Neuroinflammation

Interactive HIV-1 Tat and Morphine-Induced Synaptodendritic Injury Is Triggered through Focal Disruptions in Na+ Influx, Mitochondrial Instability, and Ca2+ Overload

(2014) S. Fitting et al.   JOURNAL OF NEUROSCIENCE

MiR-9 promotes microglial activation by targeting MCPIP1

(2014) Honghong Yao et al.   Nature Communications

Effects of chronic HIV-1 Tat exposure in the CNS: heightened vulnerability of males versus females to changes in cell numbers, synaptic integrity, and behavior

(2013) Yun Kyung Hahn et al.   Brain Structure & Function

Rare exonic deletions implicate the synaptic organizer Gephyrin (GPHN) in risk for autism, schizophrenia and seizures

(2013) Anath C. Lionel et al.   HUMAN MOLECULAR GENETICS

Exosomes Derived from HIV-1-infected Cells Contain Trans-activation Response Element RNA

(2013) Aarthi Narayanan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GB Virus C Particles Inhibit T Cell Activation via Envelope E2 Protein-Mediated Inhibition of TCR Signaling

(2013) N. Bhattarai et al.   JOURNAL OF IMMUNOLOGY

Release of Luminal Exosomes Contributes to TLR4-Mediated Epithelial Antimicrobial Defense

(2013) Guoku Hu et al.   PLoS Pathogens

Role of Endolysosomes in HIV-1 Tat-Induced Neurotoxicity

(2012) Liang Hui et al.   ASN Neuro

Synaptic Dysfunction in the Hippocampus Accompanies Learning and Memory Deficits in Human Immunodeficiency Virus Type-1 Tat Transgenic Mice

(2012) Sylvia Fitting et al.   BIOLOGICAL PSYCHIATRY

Ketone bodies protection against HIV-1 Tat-induced neurotoxicity

(2012) Liang Hui et al.   JOURNAL OF NEUROCHEMISTRY

Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation

(2012) Crystal Bethel-Brown et al.   Journal of Neuroinflammation

Human Immunodeficiency Virus Type 1 Alters Brain-Derived Neurotrophic Factor Processing in Neurons

(2012) A. Bachis et al.   JOURNAL OF NEUROSCIENCE

NIH Image to ImageJ: 25 years of image analysis

(2012) Caroline A Schneider et al.   NATURE METHODS

Culturing pyramidal neurons from the early postnatal mouse hippocampus and cortex

(2012) Gerard M J Beaudoin et al.   Nature Protocols

Platelet-Derived Growth Factor CC-Mediated Neuroprotection against HIV Tat Involves TRPC-Mediated Inactivation of GSK 3beta

(2012) Fuwang Peng et al.   PLoS One

Exosome-mediated shuttling of microRNA-29 regulates HIV Tat and morphine-mediated Neuronal dysfunction

(2012) G Hu et al.   Cell Death & Disease

HIV-1 decreases the levels of neurotrophins in human lymphocytes

(2011) Valeriya Avdoshina et al.   AIDS

Morphine Potentiates Neuropathogenesis of SIV Infection in Rhesus Macaques

(2011) Sirosh M. Bokhari et al.   Journal of Neuroimmune Pharmacology

Secretion Modification Region-Derived Peptide Disrupts HIV-1 Nef's Interaction with Mortalin and Blocks Virus and Nef Exosome Release

(2011) M. N. Shelton et al.   JOURNAL OF VIROLOGY

Neurotoxicity of Human Immunodeficiency Virus-1: Viral Proteins and Axonal Transport

(2011) Italo Mocchetti et al.   NEUROTOXICITY RESEARCH

Exosomes/microvesicles: mediators of cancer-associated immunosuppressive microenvironments

(2011) Douglas D. Taylor et al.   Seminars in Immunopathology

Interactive Comorbidity between Opioid Drug Abuse and HIV-1 Tat

(2010) Sylvia Fitting et al.   AMERICAN JOURNAL OF PATHOLOGY

Survival effect of PDGF-CC rescues neurons from apoptosis in both brain and retina by regulating GSK3β phosphorylation

(2010) Zhongshu Tang et al.   JOURNAL OF EXPERIMENTAL MEDICINE

TRPC channel-mediated neuroprotection by PDGF involves Pyk2/ERK/CREB pathway

(2009) H Yao et al.   CELL DEATH AND DIFFERENTIATION

Exosomal MicroRNA: A Diagnostic Marker for Lung Cancer

(2009) Guilherme Rabinowits et al.   Clinical Lung Cancer

 -Catenin Regulates Spine and Synapse Morphogenesis and Function in Hippocampal Neurons during Development

(2009) J. Arikkath et al.   JOURNAL OF NEUROSCIENCE

Coordinated Regulation of SIV Replication and Immune Responses in the CNS

(2009) Kenneth W. Witwer et al.   PLoS One

Shedding microvesicles: artefacts no more

(2009) Emanuele Cocucci et al.   TRENDS IN CELL BIOLOGY

Human Immunodeficiency Virus Protein Tat Induces Synapse Loss via a Reversible Process That Is Distinct from Cell Death

(2008) H. J. Kim et al.   JOURNAL OF NEUROSCIENCE

Erbin Controls Dendritic Morphogenesis by Regulating Localization of  -Catenin

(2008) J. Arikkath et al.   JOURNAL OF NEUROSCIENCE

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

Emerging restorative treatments for Parkinson's disease

(2008) Tomas Deierborg et al.   PROGRESS IN NEUROBIOLOGY