Dynamic Control of Synaptic Adhesion and Organizing Molecules in Synaptic Plasticity

Astrocytes Assemble Thalamocortical Synapses by Bridging NRX1α and NL1 via Hevin

(2016) Sandeep K. Singh et al.   CELL

Current knowledge on the genetics of autism and propositions for future research

(2016) Thomas Bourgeron   COMPTES RENDUS BIOLOGIES

Neural plasticity and behavior - sixty years of conceptual advances

(2016) J. David Sweatt   JOURNAL OF NEUROCHEMISTRY

Neuroligin-2 and the tightrope of excitation/inhibition balance in the prefrontal cortex

(2016) Alice M. S. Durieux et al.   JOURNAL OF NEUROPHYSIOLOGY

SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3–LAR adhesion

(2016) Eunkyung Lie et al.   Nature Communications

LRRTM3 Regulates Excitatory Synapse Development through Alternative Splicing and Neurexin Binding

(2016) Ji Won Um et al.   Cell Reports

Human cell adhesion molecules: annotated functional subtypes and overrepresentation of addiction-associated genes

(2015) Xiaoming Zhong et al.   Annals of the New York Academy of Sciences

Genetic Risk for Schizophrenia: Convergence on Synaptic Pathways Involved in Plasticity

(2015) Jeremy Hall et al.   BIOLOGICAL PSYCHIATRY

β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling

(2015) Garret R. Anderson et al.   CELL

Neuronal Activity Promotes Glioma Growth through Neuroligin-3 Secretion

(2015) Humsa S. Venkatesh et al.   CELL

Glia in mammalian development and disease

(2015) J. Bradley Zuchero et al.   DEVELOPMENT

The Regulation of Synaptic Protein Turnover

(2015) Beatriz Alvarez-Castelao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteomics of the Synapse – A Quantitative Approach to Neuronal Plasticity

(2015) Daniela C. Dieterich et al.   MOLECULAR & CELLULAR PROTEOMICS

Specification of synaptic connectivity by cell surface interactions

(2015) Joris de Wit et al.   NATURE REVIEWS NEUROSCIENCE

Single-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin Isoforms

(2015) Marc V. Fuccillo et al.   NEURON

Topographic Mapping of the Synaptic Cleft into Adhesive Nanodomains

(2015) Karen Perez de Arce et al.   NEURON

Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses

(2015) Bo Zhang et al.   NEURON

The Autism Related Protein Contactin-Associated Protein-Like 2 (CNTNAP2) Stabilizes New Spines: An In Vivo Mouse Study

(2015) Amos Gdalyahu et al.   PLoS One

The balancing act of GABAergic synapse organizers

(2015) Jaewon Ko et al.   TRENDS IN MOLECULAR MEDICINE

Activity dependent CAM cleavage and neurotransmission

(2015) Katherine Conant et al.   Frontiers in Cellular Neuroscience

Structural homeostasis in the nervous system: a balancing act for wiring plasticity and stability

(2015) Jun Yin et al.   Frontiers in Cellular Neuroscience

Structural Components of Synaptic Plasticity and Memory Consolidation

(2015) Craig H. Bailey et al.   Cold Spring Harbor Perspectives in Biology

Protocadherins branch out: Multiple roles in dendrite development

(2015) Austin B Keeler et al.   Cell Adhesion & Migration

Structure of Slitrk2–PTPδ complex reveals mechanisms for splicing-dependent trans-synaptic adhesion

(2015) Atsushi Yamagata et al.   Scientific Reports

Splicing-Dependent Trans-synaptic SALM3–LAR-RPTP Interactions Regulate Excitatory Synapse Development and Locomotion

(2015) Yan Li et al.   Cell Reports

Quantitative isoform-profiling of highly diversified recognition molecules

(2015) Dietmar Schreiner et al.   eLife

Astrocyte Regulation of Synaptic Behavior

(2014) Nicola J. Allen   Annual Review of Cell and Developmental Biology

Single-Cell Identity Generated by Combinatorial Homophilic Interactions between α, β, and γ Protocadherins

(2014) Chan Aye Thu et al.   CELL

Dystroglycan Binding to α-Neurexin Competes with Neurexophilin-1 and Neuroligin in the Brain

(2014) Carsten Reissner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calsyntenin-3 Molecular Architecture and Interaction with Neurexin 1α

(2014) Zhuoyang Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Calcium Signaling Induces Expression of the Synaptic OrganizersLrrtm1andLrrtm2

(2014) Stefanie N. Hayer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

De novo mutations in schizophrenia implicate synaptic networks

(2014) Menachem Fromer et al.   NATURE

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

Targeted Combinatorial Alternative Splicing Generates Brain Region-Specific Repertoires of Neurexins

(2014) Dietmar Schreiner et al.   NEURON

Dystroglycan mediates homeostatic synaptic plasticity at GABAergic synapses

(2014) H. Pribiag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cartography of neurexin alternative splicing mapped by single-molecule long-read mRNA sequencing

(2014) Barbara Treutlein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of neural circuit formation by leucine-rich repeat proteins

(2014) Joris de Wit et al.   TRENDS IN NEUROSCIENCES

Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion

(2014) Ji Won Um et al.   Nature Communications

Calsyntenins Function as Synaptogenic Adhesion Molecules in Concert with Neurexins

(2014) Ji Won Um et al.   Cell Reports

Presynaptic Neurexin-3 Alternative Splicing trans-Synaptically Controls Postsynaptic AMPA Receptor Trafficking

(2013) Jason Aoto et al.   CELL

Shining a light on CNTNAP2: complex functions to complex disorders

(2013) Pedro Rodenas-Cuadrado et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Contactins in the neurobiology of autism

(2013) Amila Zuko et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development

(2013) Katherine L. Pettem et al.   JOURNAL OF CELL BIOLOGY

Synapse maturation by activity-dependent ectodomain shedding of SIRPα

(2013) Anna B Toth et al.   NATURE NEUROSCIENCE

CaMKII phosphorylation of neuroligin-1 regulates excitatory synapses

(2013) Michael A Bemben et al.   NATURE NEUROSCIENCE

The Specific α-Neurexin Interactor Calsyntenin-3 Promotes Excitatory and Inhibitory Synapse Development

(2013) Katherine L. Pettem et al.   NEURON

Soluble ICAM-5, a Product of Activity Dependent Proteolysis, Increases mEPSC Frequency and Dendritic Expression of GluA1

(2013) Irina Lonskaya et al.   PLoS One

N-Cadherin Relocalizes from the Periphery to the Center of the Synapse after Transient Synaptic Stimulation in Hippocampal Neurons

(2013) Patricia T. Yam et al.   PLoS One

In vivo quantitative proteomics of somatosensory cortical synapses shows which protein levels are modulated by sensory deprivation

(2013) M. T. Butko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Slitrks control excitatory and inhibitory synapse formation with LAR receptor protein tyrosine phosphatases

(2013) Y. S. Yim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuro-glial interactions at the nodes of Ranvier: implication in health and diseases

(2013) Catherine Faivre-Sarrailh et al.   Frontiers in Cellular Neuroscience

Neurexins

(2013) Carsten Reissner et al.   GENOME BIOLOGY

SynaptomeDB: an ontology-based knowledgebase for synaptic genes

(2012) Mehdi Pirooznia et al.   BIOINFORMATICS

Cadherins and neuropsychiatric disorders

(2012) Christoph Redies et al.   BRAIN RESEARCH

Synaptopathies: diseases of the synaptome

(2012) Seth GN Grant   CURRENT OPINION IN NEUROBIOLOGY

High Affinity Neurexin Binding to Cell Adhesion G-protein-coupled Receptor CIRL1/Latrophilin-1 Produces an Intercellular Adhesion Complex

(2012) Antony A. Boucard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Exonal Elements and Factors Involved in the Depolarization-Induced Alternative Splicing of Neurexin 2

(2012) G. Rozic et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Interleukin-1 Receptor Accessory Protein Organizes Neuronal Synaptogenesis as a Cell Adhesion Molecule

(2012) T. Yoshida et al.   JOURNAL OF NEUROSCIENCE

Selective control of inhibitory synapse development by Slitrk3-PTPδ trans-synaptic interaction

(2012) Hideto Takahashi et al.   NATURE NEUROSCIENCE

Proteolytic Remodeling of the Synaptic Cell Adhesion Molecules (CAMs) by Metzincins in Synaptic Plasticity

(2012) Malgorzata Bajor et al.   NEUROCHEMICAL RESEARCH

Transsynaptic Signaling by Activity-Dependent Cleavage of Neuroligin-1

(2012) Rui T. Peixoto et al.   NEURON

Activity-Dependent Proteolytic Cleavage of Neuroligin-1

(2012) Kunimichi Suzuki et al.   NEURON

Distinct roles of neuroligin-1 and SynCAM1 in synapse formation and function in primary hippocampal neuronal cultures

(2012) S.D. Burton et al.   NEUROSCIENCE

MDGAs interact selectively with neuroligin-2 but not other neuroligins to regulate inhibitory synapse development

(2012) K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SAM68 Regulates Neuronal Activity-Dependent Alternative Splicing of Neurexin-1

(2011) Takatoshi Iijima et al.   CELL

Neuroligins/LRRTMs prevent activity- and Ca2+/calmodulin-dependent synapse elimination in cultured neurons

(2011) Jaewon Ko et al.   JOURNAL OF CELL BIOLOGY

IL-1 Receptor Accessory Protein-Like 1 Associated with Mental Retardation and Autism Mediates Synapse Formation by Trans-Synaptic Interaction with Protein Tyrosine Phosphatase  

(2011) T. Yoshida et al.   JOURNAL OF NEUROSCIENCE

Postsynaptic TrkC and Presynaptic PTPσ Function as a Bidirectional Excitatory Synaptic Organizing Complex

(2011) Hideto Takahashi et al.   NEURON

Presenilin/γ-Secretase Regulates Neurexin Processing at Synapses

(2011) Carlos A. Saura et al.   PLoS One

Chronic Morphine Alters the Presynaptic Protein Profile: Identification of Novel Molecular Targets Using Proteomics and Network Analysis

(2011) Noura S. Abul-Husn et al.   PLoS One

Calcium-dependent dynamics of cadherin interactions at cell-cell junctions

(2011) S. A. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivo

(2011) G. J. Soler-Llavina et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Structure of Neurexin 1α Reveals Features Promoting a Role as Synaptic Organizer

(2011) Fang Chen et al.   STRUCTURE

Synaptopathy: dysfunction of synaptic function?

(2010) Nils Brose et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Activity-dependent α-Cleavage of Nectin-1 Is Mediated by A Disintegrin and Metalloprotease 10 (ADAM10)

(2010) Jinsook Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Processing of the Synaptic Cell Adhesion Molecule Neurexin-3β by Alzheimer Disease α- and γ-Secretases

(2010) Nathalie Bot et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NMDA-Mediated Regulation of DSCAM Dendritic Local Translation Is Lost in a Mouse Model of Down's Syndrome

(2010) A. Alves-Sampaio et al.   JOURNAL OF NEUROSCIENCE

Neuroligin 1 Is Dynamically Exchanged at Postsynaptic Sites

(2010) I. U. Schapitz et al.   JOURNAL OF NEUROSCIENCE

LRRTMs and Neuroligins Bind Neurexins with a Differential Code to Cooperate in Glutamate Synapse Development

(2010) T. J. Siddiqui et al.   JOURNAL OF NEUROSCIENCE

Splice Form Dependence of β-Neurexin/Neuroligin Binding Interactions

(2010) Jesko Koehnke et al.   NEURON

Differential dynamics and activity-dependent regulation of  - and  -neurexins at developing GABAergic synapses

(2010) Y. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combinatorial homophilic interaction between  -protocadherin multimers greatly expands the molecular diversity of cell adhesion

(2010) D. Schreiner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thrombospondin 1 accelerates synaptogenesis in hippocampal neurons through neuroligin 1

(2009) Junyu Xu et al.   NATURE NEUROSCIENCE

LRRTM2 Functions as a Neurexin Ligand in Promoting Excitatory Synapse Formation

(2009) Jaewon Ko et al.   NEURON

Neuroligins and neurexins link synaptic function to cognitive disease

(2008) Thomas C. Südhof   NATURE

G2Cdb: the Genes to Cognition database

(2008) M. D. R. Croning et al.   NUCLEIC ACIDS RESEARCH

Regulation of Neurexin 1β Tertiary Structure and Ligand Binding through Alternative Splicing

(2008) Kaiser C. Shen et al.   STRUCTURE