Middle East respiratory syndrome coronavirus-encoded ORF8b strongly antagonizes IFN-β promoter activation: its implication for vaccine design

Cell Type-Specific Interferon-γ-mediated Antagonism of KSHV Lytic Replication

(2019) Mi-Kyung Park et al.   Scientific Reports

Antagonism of dsRNA-Induced Innate Immune Pathways by NS4a and NS4b Accessory Proteins during MERS Coronavirus Infection

(2019) Courtney E. Comar et al.   mBio

Host Determinants of MERS-CoV Transmission and Pathogenesis

(2019) W. Widagdo et al.   Viruses-Basel

Interferon Regulatory Factor 3-Mediated Signaling Limits Middle-East Respiratory Syndrome (MERS) Coronavirus Propagation in Cells from an Insectivorous Bat

(2019) Arinjay Banerjee et al.   Viruses-Basel

Antiviral activity of double-stranded RNA–binding protein PACT against influenza A virus mediated via suppression of viral RNA polymerase

(2018) Chi-Ping Chan et al.   FASEB JOURNAL

Fatal swine acute diarrhoea syndrome caused by an HKU2-related coronavirus of bat origin

(2018) Peng Zhou et al.   NATURE

High fatality rates and associated factors in two hospital outbreaks of MERS in Daejeon, the Republic of Korea

(2017) Hae-Sung Nam et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

Middle East respiratory syndrome coronavirus (MERS-CoV) outbreak in South Korea, 2015: epidemiology, characteristics and public health implications

(2017) K.H. Kim et al.   JOURNAL OF HOSPITAL INFECTION

PACT Facilitates RNA-Induced Activation of MDA5 by Promoting MDA5 Oligomerization

(2017) Pak-Yin Lui et al.   JOURNAL OF IMMUNOLOGY

Primary lymphocyte infection models for KSHV and its putative tumorigenesis mechanisms in B cell lymphomas

(2017) Sangmin Kang et al.   JOURNAL OF MICROBIOLOGY

Host Innate Immunity against Hepatitis E Virus and Viral Evasion Mechanisms

(2017) Sangmin Kang et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Bats are global reservoir for deadly coronaviruses

(2017) Amy Maxmen   NATURE

Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract

(2016) David K. Meyerholz et al.   AMERICAN JOURNAL OF PATHOLOGY

Infection models of human norovirus: challenges and recent progress

(2016) Sangdo Ha et al.   ARCHIVES OF VIROLOGY

Transgenic expression of non-structural genes of Theiler’s virus suppresses initial viral replication and pathogenesis of demyelination

(2016) Hyun Seok Kang et al.   Journal of Neuroinflammation

Bats as Viral Reservoirs

(2016) David T.S. Hayman   Annual Review of Virology

Transmission characteristics of MERS and SARS in the healthcare setting: a comparative study

(2015) Gerardo Chowell et al.   BMC Medicine

Middle East Respiratory Syndrome Coronavirus: Another Zoonotic Betacoronavirus Causing SARS-Like Disease

(2015) Jasper F. W. Chan et al.   CLINICAL MICROBIOLOGY REVIEWS

OX40 and 4-1BB downregulate Kaposi's sarcoma-associated herpesvirus replication in lymphatic endothelial cells, but 4-1BB and not OX40 inhibits viral replication in B-cells

(2015) Min Cho et al.   JOURNAL OF GENERAL VIROLOGY

PACT- and RIG-I-Dependent Activation of Type I Interferon Production by a Defective Interfering RNA Derived from Measles Virus Vaccine

(2015) Ting-Hin Ho et al.   JOURNAL OF VIROLOGY

Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation

(2015) S. Liu et al.   SCIENCE

Middle East respiratory syndrome (MERS) in Asia: lessons gleaned from the South Korean outbreak

(2015) Poh Lian Lim   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targets

(2015) Yang Yang et al.   Scientific Reports

The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signalling

(2014) K. L. Matthews et al.   JOURNAL OF GENERAL VIROLOGY

Pathogenesis of Middle East respiratory syndrome coronavirus

(2014) Judith MA van den Brand et al.   JOURNAL OF PATHOLOGY

Middle East Respiratory Syndrome Coronavirus 4a Protein Is a Double-Stranded RNA-Binding Protein That Suppresses PACT-Induced Activation of RIG-I and MDA5 in the Innate Antiviral Response

(2014) K.-L. Siu et al.   JOURNAL OF VIROLOGY

Antiviral immunity via RIG-I-mediated recognition of RNA bearing 5′-diphosphates

(2014) Delphine Goubau et al.   NATURE

Targeting Membrane-Bound Viral RNA Synthesis Reveals Potent Inhibition of Diverse Coronaviruses Including the Middle East Respiratory Syndrome Virus

(2014) Anna Lundin et al.   PLoS Pathogens

In Vivo Ligands of MDA5 and RIG-I in Measles Virus-Infected Cells

(2014) Simon Runge et al.   PLoS Pathogens

Suppression of PACT-Induced Type I Interferon Production by Herpes Simplex Virus 1 Us11 Protein

(2013) C. Kew et al.   JOURNAL OF VIROLOGY

Human Cell Tropism and Innate Immune System Interactions of Human Respiratory Coronavirus EMC Compared to Those of Severe Acute Respiratory Syndrome Coronavirus

(2013) F. Zielecki et al.   JOURNAL OF VIROLOGY

Middle East Respiratory Syndrome Coronavirus Accessory Protein 4a Is a Type I Interferon Antagonist

(2013) D. Niemeyer et al.   JOURNAL OF VIROLOGY

Paramyxovirus V Proteins Disrupt the Fold of the RNA Sensor MDA5 to Inhibit Antiviral Signaling

(2013) C. Motz et al.   SCIENCE

The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonists

(2013) Yang Yang et al.   Protein & Cell

One-Step Sequence- and Ligation-Independent Cloning as a Rapid and Versatile Cloning Method for Functional Genomics Studies

(2012) Jae-Yeon Jeong et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genomic Characterization of a Newly Discovered Coronavirus Associated with Acute Respiratory Distress Syndrome in Humans

(2012) S. van Boheemen et al.   mBio

The Double-Stranded RNA-Binding Protein PACT Functions as a Cellular Activator of RIG-I to Facilitate Innate Antiviral Response

(2011) Kin-Hang Kok et al.   Cell Host & Microbe

Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

(2011) Roland Züst et al.   NATURE IMMUNOLOGY

Activation of IFN-β expression by a viral mRNA through RNase L and MDA5

(2011) Priya Luthra et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutations Abrogating VP35 Interaction with Double-Stranded RNA Render Ebola Virus Avirulent in Guinea Pigs

(2010) K. C. Prins et al.   JOURNAL OF VIROLOGY

Phylogenetic perspectives on the epidemiology and origins of SARS and SARS-like coronaviruses

(2009) Chi Wai Yip et al.   INFECTION GENETICS AND EVOLUTION

Ebola Virus Protein VP35 Impairs the Function of Interferon Regulatory Factor-Activating Kinases IKK  and TBK-1

(2009) K. C. Prins et al.   JOURNAL OF VIROLOGY

The IKK-related kinases: from innate immunity to oncogenesis

(2008) Jean-François Clément et al.   CELL RESEARCH

Are the IKKs and IKK-related kinases TBK1 and IKK-ɛ similarly activated?

(2008) Tieu-Lan Chau et al.   TRENDS IN BIOCHEMICAL SCIENCES