Fetal T Cell Activation in the Amniotic Cavity during Preterm Labor: A Potential Mechanism for a Subset of Idiopathic Preterm Birth

Memory CD4+ T cells are generated in the human fetal intestine

(2019) Na Li et al.   NATURE IMMUNOLOGY

Effector and Activated T Cells Induce Preterm Labor and Birth That Is Prevented by Treatment with Progesterone

(2019) Marcia Arenas-Hernandez et al.   JOURNAL OF IMMUNOLOGY

Are B Cells Altered in the Decidua of Women with Preterm or Term Labor?

(2019) Yaozhu Leng et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Cellular immune responses in amniotic fluid of women with preterm labor and intra‐amniotic infection or intra‐amniotic inflammation

(2019) Nardhy Gomez‐Lopez et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Mortality and pulmonary outcomes of extremely preterm infants exposed to antenatal corticosteroids

(2018) Colm P. Travers et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Innate lymphoid cells at the human maternal-fetal interface in spontaneous preterm labor

(2018) Yi Xu et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

The immunophenotype of amniotic fluid leukocytes in normal and complicated pregnancies

(2018) Nardhy Gomez-Lopez et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Alloreactive fetal T cells promote uterine contractility in preterm labor via IFN-γ and TNF-α

(2018) Michela Frascoli et al.   Science Translational Medicine

Inflammation-Induced Adverse Pregnancy and Neonatal Outcomes Can Be Improved by the Immunomodulatory Peptide Exendin-4

(2018) Valeria Garcia-Flores et al.   Frontiers in Immunology

Inflammasome activation during spontaneous preterm labor with intra-amniotic infection or sterile intra-amniotic inflammation

(2018) Nardhy Gomez-Lopez et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Decidual stromal cell-derived PGE2 regulates macrophage responses to microbial threat

(2018) Lisa M. Rogers et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Human β-defensin-1: A natural antimicrobial peptide present in amniotic fluid that is increased in spontaneous preterm labor with intra-amniotic infection

(2018) Aneesha Varrey et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Inhibition of the NLRP3 inflammasome can prevent sterile intra-amniotic inflammation, preterm labor/birth and adverse neonatal outcomes†

(2018) Nardhy Gomez-Lopez et al.   BIOLOGY OF REPRODUCTION

Inflammation-Induced Intra-Amniotic inflammation induces preterm birth by Activating the NLRP3 inflammasome†

(2018) Jonathan Faro et al.   BIOLOGY OF REPRODUCTION

Global, regional, and national estimates of levels of preterm birth in 2014: a systematic review and modelling analysis

(2018) Saifon Chawanpaiboon et al.   Lancet Global Health

Decidual T Cells Exhibit a Highly Differentiated Phenotype and Demonstrate Potential Fetal Specificity and a Strong Transcriptional Response to IFN

(2017) Richard M. Powell et al.   JOURNAL OF IMMUNOLOGY

Viral Infection Sensitizes Human Fetal Membranes to Bacterial Lipopolysaccharide by MERTK Inhibition and Inflammasome Activation

(2017) Sarah N. Cross et al.   JOURNAL OF IMMUNOLOGY

In Utero Exposure to Histological Chorioamnionitis Primes the Exometabolomic Profiles of Preterm CD4+T Lymphocytes

(2017) Poojitha Matta et al.   JOURNAL OF IMMUNOLOGY

Antenatal Suppression of IL-1 Protects against Inflammation-Induced Fetal Injury and Improves Neonatal and Developmental Outcomes in Mice

(2017) Mathieu Nadeau-Vallée et al.   JOURNAL OF IMMUNOLOGY

Fetal-to-maternal signaling in the timing of birth

(2017) Carole R. Mendelson et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Mixed signature of activation and dysfunction allows human decidual CD8+T cells to provide both tolerance and immunity

(2017) Anita van der Zwan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Role for the Inflammasome in Spontaneous Preterm Labor With Acute Histologic Chorioamnionitis

(2017) Nardhy Gomez-Lopez et al.   Reproductive Sciences

Preterm neonatal morbidity and mortality by gestational age: a contemporary cohort

(2016) Tracy A. Manuck et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5

(2016) Michela Frascoli et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide-Induced Chorioamnionitis Promotes IL-1–Dependent Inflammatory FOXP3+CD4+T Cells in the Fetal Rhesus Macaque

(2016) Cesar M. Rueda et al.   JOURNAL OF IMMUNOLOGY

Immune Modifications in Fetal Membranes Overlying the Cervix Precede Parturition in Humans

(2016) Louis Marcellin et al.   JOURNAL OF IMMUNOLOGY

Invariant NKT Cell Activation Induces Late Preterm Birth That Is Attenuated by Rosiglitazone

(2016) Derek St. Louis et al.   JOURNAL OF IMMUNOLOGY

Fetal CD103+IL-17–Producing Group 3 Innate Lymphoid Cells Represent the Dominant Lymphocyte Subset in Human Amniotic Fluid

(2016) Nicole Marquardt et al.   JOURNAL OF IMMUNOLOGY

An M1-like Macrophage Polarization in Decidual Tissue during Spontaneous Preterm Labor That Is Attenuated by Rosiglitazone Treatment

(2016) Yi Xu et al.   JOURNAL OF IMMUNOLOGY

Pro-inflammatory immune responses in leukocytes of premature infants exposed to maternal chorioamnionitis or funisitis

(2016) Courtney M. Jackson et al.   PEDIATRIC RESEARCH

Neutrophil Extracellular Traps in the Amniotic Cavity of Women with Intra-Amniotic Infection: A New Mechanism of Host Defense

(2016) Nardhy Gomez-Lopez et al.   Reproductive Sciences

Evidence of perturbations of the cytokine network in preterm labor

(2015) Roberto Romero et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance

(2015) Chong Jai Kim et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Classification of placental lesions

(2015) Raymond W. Redline   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Intra-Amniotic Administration of HMGB1 Induces Spontaneous Preterm Labor and Birth

(2015) Nardhy Gomez-Lopez et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

An imbalance between innate and adaptive immune cells at the maternal–fetal interface occurs prior to endotoxin-induced preterm birth

(2015) Marcia Arenas-Hernandez et al.   Cellular & Molecular Immunology

The Distribution of Clinical Phenotypes of Preterm Birth Syndrome

(2015) Fernando C. Barros et al.   JAMA Pediatrics

Amniotic fluid infection, inflammation, and colonization in preterm labor with intact membranes

(2014) Teresa Cobo et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Prevalence and Clinical Significance of Sterile Intra-amniotic Inflammation in Patients with Preterm Labor and Intact Membranes

(2014) Roberto Romero et al.   AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Sterile and microbial-associated intra-amniotic inflammation in preterm prelabor rupture of membranes

(2014) Roberto Romero et al.   Journal of Maternal-Fetal & Neonatal Medicine

Preterm labor: One syndrome, many causes

(2014) R. Romero et al.   SCIENCE

Fetal Immune Response to Chorioamnionitis

(2014) Pietro Presicce et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Amniotic fluid infection, inflammation, and colonization in preterm labor with intact membranes

(2013) C. Andrew Combs et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis

(2013) Lu Xue et al.   BMC GENOMICS

A hemolytic pigment of Group B Streptococcus allows bacterial penetration of human placenta

(2013) Christopher Whidbey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Damage-associated molecular patterns (DAMPs) in preterm labor with intact membranes and preterm PROM: a study of the alarmin HMGB1

(2012) Roberto Romero et al.   Journal of Maternal-Fetal & Neonatal Medicine

Long-term neurodevelopmental outcomes after intrauterine and neonatal insults: a systematic review

(2012) Michael K Mwaniki et al.   LANCET

National, regional, and worldwide estimates of preterm birth rates in the year 2010 with time trends since 1990 for selected countries: a systematic analysis and implications

(2012) Hannah Blencowe et al.   LANCET

Changes in Fetal Thymic Immune Cell Populations in a Sheep Model of Intrauterine Inflammation

(2012) Jacqueline M. Melville et al.   Reproductive Sciences

Preterm Labor and Chorioamnionitis Are Associated with Neonatal T Cell Activation

(2011) Angel A. Luciano et al.   PLoS One

The frequency, clinical significance and pathological features of chronic chorioamnionitis: a lesion associated with spontaneous preterm birth

(2010) Chong Jai Kim et al.   MODERN PATHOLOGY

Indications for delivery and short-term neonatal outcomes in late preterm as compared with term births

(2009) Jeffrey M. Lubow et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Minireview: Fetal-Maternal Hormonal Signaling in Pregnancy and Labor

(2009) Carole R. Mendelson   MOLECULAR ENDOCRINOLOGY

Ureaplasma parvum or Mycoplasma hominis as Sole Pathogens Cause Chorioamnionitis, Preterm Delivery, and Fetal Pneumonia in Rhesus Macaques

(2009) Miles J. Novy et al.   Reproductive Sciences

Amniotic fluid heat shock protein 70 concentration in histologic chorioamnionitis, term and preterm parturition

(2008) Tinnakorn Chaiworapongsa et al.   Journal of Maternal-Fetal & Neonatal Medicine

Epidemiology and causes of preterm birth

(2008) Robert L Goldenberg et al.   LANCET