Mycobacterium tuberculosis PPE2 Protein Interacts with p67phox and Inhibits Reactive Oxygen Species Production

Early clearance of Mycobacterium tuberculosis is associated with increased innate immune responses

(2019) Ayesha J Verrall et al.   JOURNAL OF INFECTIOUS DISEASES

Turning off NADPH oxidase-2 by impeding p67 phox activation in infected mouse macrophages reduced viral entry and inflammation

(2018) Nathalie Lejal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The β 2 Integrin Mac-1 Induces Protective LC3-Associated Phagocytosis of Listeria monocytogenes

(2018) Alexander Gluschko et al.   Cell Host & Microbe

Mycobacterium tuberculosis acyl carrier protein inhibits macrophage apoptotic death by modulating the reactive oxygen species/c-Jun N-terminal kinase pathway

(2018) Seungwha Paik et al.   MICROBES AND INFECTION

Untargeted metabolomics reveals a new mode of action of pretomanid (PA-824)

(2018) Rafael Baptista et al.   Scientific Reports

The PPE2 protein of Mycobacterium tuberculosis translocates to host nucleus and inhibits nitric oxide production

(2017) Khalid Hussain Bhat et al.   Scientific Reports

Redox chemistry of Mycobacterium tuberculosis alkylhydroperoxide reductase E (AhpE): Structural and mechanistic insight into a mycoredoxin-1 independent reductive pathway of AhpE via mycothiol

(2016) Arvind Kumar et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ergothioneine Maintains Redox and Bioenergetic Homeostasis Essential for Drug Susceptibility and Virulence of Mycobacterium tuberculosis

(2016) Vikram Saini et al.   Cell Reports

Insufficient Generation of Mycobactericidal Mediators and Inadequate Level of Phagosomal Maturation Are Related with Susceptibility to Virulent Mycobacterium tuberculosis Infection in Mouse Macrophages

(2016) Hyo-Ji Lee et al.   Frontiers in Microbiology

The Oxidative Stress Network of Mycobacterium tuberculosis Reveals Coordination between Radical Detoxification Systems

(2015) Subhalaxmi Nambi et al.   Cell Host & Microbe

Macrophage takeover and the host–bacilli interplay during tuberculosis

(2015) Khalid Hussain Bhat et al.   Future Microbiology

Phylogeny to function: PE/PPE protein evolution and impact onMycobacterium tuberculosispathogenicity

(2015) S. Fishbein et al.   MOLECULAR MICROBIOLOGY

Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus

(2015) Satoshi Uchiyama et al.   Frontiers in Immunology

Assembly of phagocyte NADPH oxidase: A concerted binding process?

(2014) Gilda Karimi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Reactive oxygen and nitrogen species during viral infections

(2014) C. G. Molteni et al.   FREE RADICAL RESEARCH

NADPH Oxidase Promotes Neutrophil Extracellular Trap Formation in Pulmonary Aspergillosis

(2014) Marc Röhm et al.   INFECTION AND IMMUNITY

Molecular Insights of p47phoxPhosphorylation Dynamics in the Regulation of NADPH Oxidase Activation and Superoxide Production

(2014) Daniel N. Meijles et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Silico Prediction of Escherichia coli Proteins Targeting the Host Cell Nucleus, with Special Reference to Their Role in Colon Cancer Etiology

(2014) Abdul Arif Khan   JOURNAL OF COMPUTATIONAL BIOLOGY

Human Classical Monocytes Control the Intracellular Stage of Leishmania braziliensis by Reactive Oxygen Species

(2014) Fernanda O. Novais et al.   JOURNAL OF INFECTIOUS DISEASES

NRROS negatively regulates reactive oxygen species during host defence and autoimmunity

(2014) Rajkumar Noubade et al.   NATURE

Bacillus Calmette-Guerin Infection in NADPH Oxidase Deficiency: Defective Mycobacterial Sequestration and Granuloma Formation

(2014) Christine Deffert et al.   PLoS Pathogens

Are Reactive Oxygen Species Always Detrimental to Pathogens?

(2013) Claudia N. Paiva et al.   ANTIOXIDANTS & REDOX SIGNALING

TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species

(2013) Francisco J. Roca et al.   CELL

Assembly of NADPH Oxidase in Human Neutrophils Is Modulated by the Opacity-Associated Protein Expression State of Neisseria gonorrhoeae

(2013) Asya Smirnov et al.   INFECTION AND IMMUNITY

Reactive-Oxygen-Species-Mediated P. aeruginosa Killing Is Functional in Human Cystic Fibrosis Macrophages

(2013) Noemi Cifani et al.   PLoS One

Mycobacterium tuberculosis is extraordinarily sensitive to killing by a vitamin C-induced Fenton reaction

(2013) Catherine Vilchèze et al.   Nature Communications

Strain specific transcriptional response in Mycobacterium tuberculosis infected macrophages

(2012) Mi-Sun Koo et al.   Cell Communication and Signaling

Neutrophils Exert Protection in the Early Tuberculous Granuloma by Oxidative Killing of Mycobacteria Phagocytosed from Infected Macrophages

(2012) Chao-Tsung Yang et al.   Cell Host & Microbe

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

(2012) Diane Houben et al.   CELLULAR MICROBIOLOGY

Escape of Mycobacterium tuberculosis from oxidative killing by neutrophils

(2012) Björn Corleis et al.   CELLULAR MICROBIOLOGY

SH3 domain ligand binding: What's the consensus and where's the specificity?

(2012) Kalle Saksela et al.   FEBS LETTERS

Reactive Oxygen Species Produced by the NADPH Oxidase 2 Complex in Monocytes Protect Mice from Bacterial Infections

(2012) A. Pizzolla et al.   JOURNAL OF IMMUNOLOGY

Galectin-3 is essential for reactive oxygen species production by peritoneal neutrophils from mice infected with a virulent strain of Toxoplasma gondii

(2012) C. M. O. S. ALVES et al.   PARASITOLOGY

Role of PPE18 Protein in Intracellular Survival and Pathogenicity of Mycobacterium tuberculosis in Mice

(2012) Khalid Hussain Bhat et al.   PLoS One

Escape from the Phagosome: The Explanation for MHC-I Processing of Mycobacterial Antigens?

(2012) Melanie J. Harriff et al.   Frontiers in Immunology

Listeriolysin O Suppresses Phospholipase C-Mediated Activation of the Microbicidal NADPH Oxidase to Promote Listeria monocytogenes Infection

(2011) Grace Y. Lam et al.   Cell Host & Microbe

Significant Biological Role of Sp1 Transactivation in Multiple Myeloma

(2011) M. Fulciniti et al.   CLINICAL CANCER RESEARCH

Global Profiling of Reactive Oxygen and Nitrogen Species in Biological Systems

(2011) Jacek Zielonka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

β-Glucans inhibit intracellular growth of Mycobacterium bovis BCG but not virulent Mycobacterium tuberculosis in human macrophages

(2011) Bret E. Betz et al.   MICROBIAL PATHOGENESIS

Mycobacterium tuberculosis Induces an Atypical Cell Death Mode to Escape from Infected Macrophages

(2011) Jinhee Lee et al.   PLoS One

A Family of IFN- -Inducible 65-kD GTPases Protects Against Bacterial Infection

(2011) B.-H. Kim et al.   SCIENCE

Suppressing production of reactive oxygen species (ROS) for influenza A virus therapy

(2011) Ross Vlahos et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Antimicrobial Actions of Reactive Oxygen Species

(2011) F. C. Fang   mBio

Structure ofStenotrophomonas maltophiliaFeoA complexed with zinc: a unique prokaryotic SH3-domain protein that possibly acts as a bacterial ferrous iron-transport activating factor

(2010) Yi-Che Su et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

NOX2 Complex–Derived ROS as Immune Regulators

(2010) Outi Sareila et al.   ANTIOXIDANTS & REDOX SIGNALING

ROS-inhibitory activity of YopE is required for full virulence of Yersinia in mice

(2010) Warangkhana Songsungthong et al.   CELLULAR MICROBIOLOGY

Targeting NADPH-oxidase by reactive oxygen species reveals an initial sensitive step in the assembly process

(2010) Mariano A. Ostuni et al.   FREE RADICAL BIOLOGY AND MEDICINE

Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis

(2010) Ramona L. McCaffrey et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Functional Genetic Diversity among Mycobacterium tuberculosis Complex Clinical Isolates: Delineation of Conserved Core and Lineage-Specific Transcriptomes during Intracellular Survival

(2010) Susanne Homolka et al.   PLoS Pathogens

Unique Roles of DosT and DosS in DosR Regulon Induction and Mycobacterium tuberculosis Dormancy

(2009) R. W. Honaker et al.   INFECTION AND IMMUNITY

The multifunctional histone-like protein Lsr2 protects mycobacteria against reactive oxygen intermediates

(2009) R. Colangeli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells

(2008) A. R. Mantegazza et al.   BLOOD