Macrophage takeover and the host–bacilli interplay during tuberculosis

The cell envelope glycoconjugates ofMycobacterium tuberculosis

(2014) Shiva Kumar Angala et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Dectin-2 Is a Direct Receptor for Mannose-Capped Lipoarabinomannan of Mycobacteria

(2014) Akiko Yonekawa et al.   IMMUNITY

Glycerol Monomycolate Is a Novel Ligand for the Human, but Not Mouse Macrophage Inducible C-type Lectin, Mincle

(2014) Yuki Hattori et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble TNFRp75 regulates host protective immunity against Mycobacterium tuberculosis

(2014) Roanne Keeton et al.   JOURNAL OF CLINICAL INVESTIGATION

NOD2-Deficient Mice Have Impaired Resistance to Mycobacterium tuberculosis Infection through Defective Innate and Adaptive Immunity

(2014) M. Divangahi et al.   JOURNAL OF IMMUNOLOGY

PstS-1, the 38-kDaMycobacterium tuberculosisGlycoprotein, is an Adhesin, Which Binds the Macrophage Mannose Receptor and Promotes Phagocytosis

(2014) M. Esparza et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

PPE2 protein ofMycobacterium tuberculosismay inhibit nitric oxide in activated macrophages

(2013) Khalid Hussain Bhat et al.   Annals of the New York Academy of Sciences

Signalling C-Type lectin receptors, microbial recognition and immunity

(2013) J. Claire Hoving et al.   CELLULAR MICROBIOLOGY

Mycobacterium tuberculosis-specific CD8+T cells are functionally and phenotypically different between latent infection and active disease

(2013) Virginie Rozot et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

C-type Lectin MCL Is an FcRγ-Coupled Receptor that Mediates the Adjuvanticity of Mycobacterial Cord Factor

(2013) Yasunobu Miyake et al.   IMMUNITY

Tumour necrosis factor receptors and apoptosis of alveolar macrophages during early infection with attenuated and virulentMycobacterium bovis

(2013) Michele F. Rodrigues et al.   IMMUNOLOGY

Tumour necrosis factor-alpha and nitric oxide response in different categories of tuberculosis patients

(2013) U. Chakraborty et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Endocytosis ofMycobacterium tuberculosisHeat Shock Protein 60 Is Required to Induce Interleukin-10 Production in Macrophages

(2013) Nazia Parveen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

(2013) J. T. Mattila et al.   JOURNAL OF IMMUNOLOGY

Dormant Mycobacterium tuberculosis Fails To Block Phagosome Maturation and Shows Unexpected Capacity To Stimulate Specific Human T Lymphocytes

(2013) S. Mariotti et al.   JOURNAL OF IMMUNOLOGY

Inhibiting the Programmed Death 1 Pathway Rescues Mycobacterium tuberculosis–Specific Interferon γ–Producing T Cells From Apoptosis in Patients With Pulmonary Tuberculosis

(2013) Amar Singh et al.   JOURNAL OF INFECTIOUS DISEASES

N-Glycolylated Peptidoglycan Contributes to the Immunogenicity but Not Pathogenicity of Mycobacterium tuberculosis

(2013) Jesse M. Hansen et al.   JOURNAL OF INFECTIOUS DISEASES

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prominent role for T cell-derived Tumour Necrosis Factor for sustained control of Mycobacterium tuberculosis infection

(2013) Nasiema Allie et al.   Scientific Reports

Mycobacterium tuberculosisescapes from the phagosomes of infected human osteoclasts reprograms osteoclast development via dysregulation of cytokines and chemokines

(2013) Akiyoshi Hoshino et al.   Pathogens and Disease

Modeling the Mycobacterium tuberculosis Granuloma – the Critical Battlefield in Host Immunity and Disease

(2013) Evelyn Guirado et al.   Frontiers in Immunology

Unsolved Mysteries in NLR Biology

(2013) Christopher Lupfer et al.   Frontiers in Immunology

ESX-1 dependent impairment of autophagic flux byMycobacterium tuberculosisin human dendritic cells

(2012) Alessandra Romagnoli et al.   Autophagy

Extracellular M. tuberculosis DNA Targets Bacteria for Autophagy by Activating the Host DNA-Sensing Pathway

(2012) Robert O. Watson et al.   CELL

Mycobacterium tuberculosis-Driven Targeted Recalibration of Macrophage Lipid Homeostasis Promotes the Foamy Phenotype

(2012) Varshneya Singh et al.   Cell Host & Microbe

Efferocytosis Is an Innate Antibacterial Mechanism

(2012) Constance J. Martin et al.   Cell Host & Microbe

ESX-1-mediated translocation to the cytosol controls virulence of mycobacteria

(2012) Diane Houben et al.   CELLULAR MICROBIOLOGY

Infection of macrophages withMycobacterium tuberculosisinduces global modifications to phagosomal function

(2012) Maria Podinovskaia et al.   CELLULAR MICROBIOLOGY

NOD2 enhances the innate response of alveolar macrophages to Mycobacterium tuberculosis in humans

(2012) Esmeralda Juárez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mycobacterium marinum SecA2 Promotes Stable Granulomas and Induces Tumor Necrosis Factor AlphaIn Vivo

(2012) Brigitte Y. Watkins et al.   INFECTION AND IMMUNITY

The Mycobacterium tuberculosis SecA2 System Subverts Phagosome Maturation To Promote Growth in Macrophages

(2012) Jonathan Tabb Sullivan et al.   INFECTION AND IMMUNITY

Proline-Proline-Glutamic Acid (PPE) Protein Rv1168c ofMycobacterium tuberculosisAugments Transcription from HIV-1 Long Terminal Repeat Promoter

(2012) Khalid Hussain Bhat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PGE2 Induces Macrophage IL-10 Production and a Regulatory-like Phenotype via a Protein Kinase A-SIK-CRTC3 Pathway

(2012) K. F. MacKenzie et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis Modulates Macrophage Lipid-Sensing Nuclear Receptors PPAR  and TR4 for Survival

(2012) S. Mahajan et al.   JOURNAL OF IMMUNOLOGY

DNA damage in peripheral blood mononuclear cells of patients undergoing anti-tuberculosis treatment

(2012) Larissa Ragozo Cardoso de Oliveira et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β

(2012) Bibhuti B Mishra et al.   NATURE IMMUNOLOGY

Role of PPE18 Protein in Intracellular Survival and Pathogenicity of Mycobacterium tuberculosis in Mice

(2012) Khalid Hussain Bhat et al.   PLoS One

The Mycobacterium tuberculosis PE Proteins Rv0285 and Rv1386 Modulate Innate Immunity and Mediate Bacillary Survival in Macrophages

(2012) Bhavana Mishra Tiwari et al.   PLoS One

Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation

(2012) E. F. Castillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enhancement of immune response to a DNA vaccine against Mycobacterium tuberculosis Ag85B by incorporation of an autophagy inducing system

(2012) Jomkhwan Meerak et al.   VACCINE

Linking the Transcriptional Profiles and the Physiological States of Mycobacterium tuberculosis during an Extended Intracellular Infection

(2012) Kyle H. Rohde et al.   PLoS Pathogens

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

(2012) Roxane Simeone et al.   PLoS Pathogens

Nitazoxanide Stimulates Autophagy and Inhibits mTORC1 Signaling and Intracellular Proliferation of Mycobacterium tuberculosis

(2012) Karen K. Y. Lam et al.   PLoS Pathogens

Effects of Mycobacterium tuberculosis ESAT-6/CFP-10 Fusion Protein on the Autophagy Function of Mouse Macrophages

(2011) Lei Zhang et al.   DNA AND CELL BIOLOGY

Activation of the NLRP3 inflammasome byMycobacterium tuberculosisis uncoupled from susceptibility to active tuberculosis

(2011) Anca Dorhoi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The PPE18 Protein of Mycobacterium tuberculosis Inhibits NF- B/rel-Mediated Proinflammatory Cytokine Production by Upregulating and Phosphorylating Suppressor of Cytokine Signaling 3 Protein

(2011) S. Nair et al.   JOURNAL OF IMMUNOLOGY

M2 Macrophages Induced by Prostaglandin E2 and IL-6 from Cervical Carcinoma Are Switched to Activated M1 Macrophages by CD4+ Th1 Cells

(2011) M. Heusinkveld et al.   JOURNAL OF IMMUNOLOGY

Mycobacterial Secretion Systems ESX-1 and ESX-5 Play Distinct Roles in Host Cell Death and Inflammasome Activation

(2011) A. M. Abdallah et al.   JOURNAL OF IMMUNOLOGY

Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis

(2011) S M Behar et al.   Mucosal Immunology

Lysine Auxotrophy Combined with Deletion of the SecA2 Gene Results in a Safe and Highly Immunogenic Candidate Live Attenuated Vaccine for Tuberculosis

(2011) Joseph Hinchey et al.   PLoS One

Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification

(2011) D. Wong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The PE and PPE proteins of Mycobacterium tuberculosis

(2011) Sangita Mukhopadhyay et al.   TUBERCULOSIS

Inside or outside the phagosome? The controversy of the intracellular localization of Mycobacterium tuberculosis

(2011) Amanda Welin et al.   TUBERCULOSIS

The Response of Mycobacterium Tuberculosis to Reactive Oxygen and Nitrogen Species

(2011) Martin I. Voskuil et al.   Frontiers in Microbiology

NOD2 controls the nature of the inflammatory response and subsequent fate of Mycobacterium tuberculosis and M. bovis BCG in human macrophages

(2010) Michelle N. Brooks et al.   CELLULAR MICROBIOLOGY

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

(2010) Bibhuti B. Mishra et al.   CELLULAR MICROBIOLOGY

Changing Concepts of “Latent Tuberculosis Infection” in Patients Living with HIV Infection

(2010) Stephen D. Lawn et al.   Clinical & Developmental Immunology

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Src Homology 3-interacting Domain of Rv1917c ofMycobacterium tuberculosisInduces Selective Maturation of Human Dendritic Cells by Regulating PI3K-MAPK-NF-κB Signaling and Drives Th2 Immune Responses

(2010) Kushagra Bansal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Partial Redundancy of the Pattern Recognition Receptors, Scavenger Receptors, and C-Type Lectins for the Long-Term Control of Mycobacterium tuberculosis Infection

(2010) N. Court et al.   JOURNAL OF IMMUNOLOGY

Mycobacterium tuberculosis Activates Human Macrophage Peroxisome Proliferator-Activated Receptor   Linking Mannose Receptor Recognition to Regulation of Immune Responses

(2010) M. V. S. Rajaram et al.   JOURNAL OF IMMUNOLOGY

Differential polarization of alveolar macrophages and bone marrow-derived monocytes following chemically and pathogen-induced chronic lung inflammation

(2010) Elizabeth F. Redente et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Syk/CARD9-coupled receptor Dectin-1 is not required for host resistance to Mycobacterium tuberculosis in mice

(2010) Mohlopheni J. Marakalala et al.   MICROBES AND INFECTION

Eicosanoid pathways regulate adaptive immunity to Mycobacterium tuberculosis

(2010) Maziar Divangahi et al.   NATURE IMMUNOLOGY

Granuloma Formation and Host Defense in Chronic Mycobacterium tuberculosis Infection Requires PYCARD/ASC but Not NLRP3 or Caspase-1

(2010) Erin McElvania TeKippe et al.   PLoS One

Diversity in Mycobacterium tuberculosis mannosylated cell wall determinants impacts adaptation to the host

(2010) Jordi B. Torrelles et al.   TUBERCULOSIS

The Type I NADH Dehydrogenase of Mycobacterium tuberculosis Counters Phagosomal NOX2 Activity to Inhibit TNF-α-Mediated Host Cell Apoptosis

(2010) Jessica L. Miller et al.   PLoS Pathogens

PPARγ Controls Dectin-1 Expression Required for Host Antifungal Defense against Candida albicans

(2010) Amandine Galès et al.   PLoS Pathogens

Host-Detrimental Role of Esx-1-Mediated Inflammasome Activation in Mycobacterial Infection

(2010) Fredric Carlsson et al.   PLoS Pathogens

Cell-Mediated Immune Responses in Tuberculosis

(2009) Andrea M. Cooper   Annual Review of Immunology

The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

(2009) J. Muse Davis et al.   CELL

Transcriptional and inflammasome-mediated pathways for the induction of IL-1β production byMycobacterium tuberculosis

(2009) Johanneke Kleinnijenhuis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Apoptosis of macrophages during pulmonaryMycobacterium bovisinfection: correlation with intracellular bacillary load and cytokine levels

(2009) Michele F. Rodrigues et al.   IMMUNOLOGY

The Mycobacterium tuberculosis DosR Regulon Assists in Metabolic Homeostasis and Enables Rapid Recovery from Nonrespiring Dormancy

(2009) R. L. Leistikow et al.   JOURNAL OF BACTERIOLOGY

Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

(2009) Eri Ishikawa et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The PPE18 of Mycobacterium tuberculosis Interacts with TLR2 and Activates IL-10 Induction in Macrophage

(2009) S. Nair et al.   JOURNAL OF IMMUNOLOGY

The resuscitation-promoting factors ofMycobacterium tuberculosisare required for virulence and resuscitation from dormancy but are collectively dispensable for growthin vitro

(2009) Bavesh D. Kana et al.   MOLECULAR MICROBIOLOGY

New insight into the everlasting host-pathogen arms race

(2009) Coenraad Kuijl et al.   NATURE IMMUNOLOGY

Targeting of the GTPase Irgm1 to the phagosomal membrane via PtdIns(3,4)P2 and PtdIns(3,4,5)P3 promotes immunity to mycobacteria

(2009) Sangeeta Tiwari et al.   NATURE IMMUNOLOGY

Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori

(2009) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

Mycobacterium tuberculosis evades macrophage defenses by inhibiting plasma membrane repair

(2009) Maziar Divangahi et al.   NATURE IMMUNOLOGY

A replication clock for Mycobacterium tuberculosis

(2009) Wendy P Gill et al.   NATURE MEDICINE

Modeling the immune rheostat of macrophages in the lung in response to infection

(2009) J. Day et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evasion and subversion of antigen presentation byMycobacterium tuberculosis

(2009) A. Baena et al.   TISSUE ANTIGENS

Autophagy and the Immune Response to TB

(2009) J. Harris et al.   Transboundary and Emerging Diseases

Macrophage Apoptosis in Tuberculosis

(2009) Jinhee Lee et al.   YONSEI MEDICAL JOURNAL

Mycobacterium tuberculosis Prevents Inflammasome Activation

(2008) Sharon S. Master et al.   Cell Host & Microbe

Mycobacterium tuberculosisheat shock protein 60 modulates immune response to PPD by manipulating the surface expression of TLR2 on macrophages

(2008) Nooruddin Khan et al.   CELLULAR MICROBIOLOGY

Containment of aerogenicMycobacterium tuberculosis infection in mice does not require MyD88 adaptor function for TLR2, -4 and -9

(2008) Christoph Hölscher et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The NLR Gene Family: A Standard Nomenclature

(2008) Jenny P.-Y. Ting et al.   IMMUNITY

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

(2008) L. E. Via et al.   INFECTION AND IMMUNITY

Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence

(2008) Huixian Gan et al.   NATURE IMMUNOLOGY

Macrophage activation and polarization

(2007) Fernando Oneissi Martinez   Frontiers in Bioscience-Landmark

Gene expression profiles of bronchoalveolar cells in pulmonary TB

(2007) Bindu Raju et al.   TUBERCULOSIS