Bidirectional Cross-Talk between Biliary Epithelium and Th17 Cells Promotes Local Th17 Expansion and Bile Duct Proliferation in Biliary Liver Diseases

IL-17 Signaling: The Yin and the Yang

(2017) Nilesh Amatya et al.   TRENDS IN IMMUNOLOGY

The dendritic cell-T helper 17-macrophage axis controls cholangiocyte injury and disease progression in murine and human biliary atresia

(2016) Celine S. Lages et al.   HEPATOLOGY

Human intrahepatic regulatory T cells are functional, require IL-2 from effector cells for survival, and are susceptible to Fas ligand-mediated apoptosis

(2016) Yung-Yi Chen et al.   HEPATOLOGY

Protein C receptor (PROCR) is a negative regulator of Th17 pathogenicity

(2016) Yasuhiro Kishi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1

(2016) Hannah C. Jeffery et al.   JOURNAL OF HEPATOLOGY

IL-17-producing γδ T cells enhance bone regeneration

(2016) Takehito Ono et al.   Nature Communications

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

(2015) Chao Wang et al.   CELL

P0099 : Cholestatic liver fibrosis correlates with increased IL-17 and TGFβ-2 expression

(2015) M. Bueno-Topete et al.   JOURNAL OF HEPATOLOGY

Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy

(2015) Katja Gehmlich et al.   Molecular BioSystems

Clinical improvement in psoriasis with specific targeting of interleukin-23

(2015) Tamara Kopp et al.   NATURE

Chemokine Receptor Ccr6 Deficiency Alters Hepatic Inflammatory Cell Recruitment and Promotes Liver Inflammation and Fibrosis

(2015) Silvia Affò et al.   PLoS One

Interleukin 17–Producing γδT Cells Promote Hepatic Regeneration in Mice

(2014) Raghavendra Rao et al.   GASTROENTEROLOGY

Molecular phenotyping of a UK population: defining the human serum metabolome

(2014) Warwick B. Dunn et al.   Metabolomics

Aryl hydrocarbon receptor control of a disease tolerance defence pathway

(2014) Alban Bessede et al.   NATURE

Gamma Delta T-lymphocytes in Hepatitis C and Chronic Liver Disease

(2014) Neil Rajoriya et al.   Frontiers in Immunology

Increased T helper type 17 response to pathogen stimulation in patients with primary sclerosing cholangitis

(2013) Janosch Katt et al.   HEPATOLOGY

IL-12/Th1 and IL-23/Th17 biliary microenvironment in primary biliary cirrhosis: Implications for therapy

(2013) Chen-Yen Yang et al.   HEPATOLOGY

Mucosal immunity in liver autoimmunity: A comprehensive review

(2013) Palak J. Trivedi et al.   JOURNAL OF AUTOIMMUNITY

Interleukin-17A plays a pivotal role after partial hepatectomy in mice

(2013) Shinji Furuya et al.   JOURNAL OF SURGICAL RESEARCH

Primary sclerosing cholangitis

(2013) Gideon M Hirschfield et al.   LANCET

Secukinumab, a human anti-IL-17A monoclonal antibody, for moderate to severe Crohn's disease: unexpected results of a randomised, double-blind placebo-controlled trial

(2012) Wolfgang Hueber et al.   GUT

CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver

(2012) Ye Htun Oo et al.   JOURNAL OF HEPATOLOGY

CD161+CD4+ T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ

(2012) Yu-Hoi Kang   Frontiers in Immunology

Automated workflows for accurate mass-based putative metabolite identification in LC/MS-derived metabolomic datasets

(2011) M. Brown et al.   BIOINFORMATICS

Th17 cells and their associated cytokines in liver diseases

(2010) Fouad Lafdil et al.   Cellular & Molecular Immunology

Distinct Roles for CCR4 and CXCR3 in the Recruitment and Positioning of Regulatory T Cells in the Inflamed Human Liver

(2010) Y. H. Oo et al.   JOURNAL OF IMMUNOLOGY

Epithelial decision makers: in search of the 'epimmunome'

(2010) Mahima Swamy et al.   NATURE IMMUNOLOGY

Periductal interleukin-17 production in association with biliary innate immunity contributes to the pathogenesis of cholangiopathy in primary biliary cirrhosis

(2009) K. Harada et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

IL-17 and Th17 cells in human inflammatory diseases

(2009) Pierre Miossec   MICROBES AND INFECTION

The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut

(2009) C Wang et al.   Mucosal Immunology

Specific Microbiota Direct the Differentiation of IL-17-Producing T-Helper Cells in the Mucosa of the Small Intestine

(2008) Ivaylo I. Ivanov et al.   Cell Host & Microbe

Hepatic IL-17 responses in human and murine primary biliary cirrhosis

(2008) Ruth Y.Z. Lan et al.   JOURNAL OF AUTOIMMUNITY

Natural agonists for aryl hydrocarbon receptor in culture medium are essential for optimal differentiation of Th17 T cells

(2008) Marc Veldhoen et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The aryl hydrocarbon receptor links TH17-cell-mediated autoimmunity to environmental toxins

(2008) Marc Veldhoen et al.   NATURE

IL-21 and TGF-β are required for differentiation of human TH17 cells

(2008) Li Yang et al.   NATURE