Elevated TRIP13 drives the AKT/mTOR pathway to induce the progression of hepatocellular carcinoma via interacting with ACTN4

Downregulation of RNF128 activates Wnt/β-catenin signaling to induce cellular EMT and stemness via CD44 and CTTN ubiquitination in melanoma

(2019) Chuan-Yuan Wei et al.   Journal of Hematology & Oncology

TRIM44 activates the AKT/mTOR signal pathway to induce melanoma progression by stabilizing TLR4

(2019) Chuan-Yuan Wei et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

α-Actinin-4 confers radioresistance coupled invasiveness in breast cancer cells through AKT pathway

(2018) Sejal Desai et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Reptin drives tumour progression and resistance to chemotherapy in nonsmall cell lung cancer

(2018) Jan-Henrik Mikesch et al.   EUROPEAN RESPIRATORY JOURNAL

TRIP13 promotes tumor growth and is associated with poor prognosis in colorectal cancer

(2018) Nengquan Sheng et al.   Cell Death & Disease

MiR-192-5p suppresses the growth of bladder cancer cells via targeting Yin Yang 1

(2018) Decai Ji et al.   Human Cell

TRIP13 Functions in the Establishment of the Spindle Assembly Checkpoint by Replenishing O-MAD2

(2018) Hoi Tang Ma et al.   Cell Reports

Silencing TRIP13 inhibits cell growth and metastasis of hepatocellular carcinoma by activating of TGF-β1/smad3

(2018) Jianning Yao et al.   Cancer Cell International

miR-192-5p silencing by genetic aberrations is a key event in hepatocellular carcinomas with cancer stem cell features

(2018) Yuanzhuo Gu et al.   CANCER RESEARCH

Bioinformatics-based analysis reveals elevated MFSD12 as a key promoter of cell proliferation and a potential therapeutic target in melanoma

(2018) Chuan-Yuan Wei et al.   ONCOGENE

TRIP13 and APC15 drive mitotic exit by turnover of interphase- and unattached kinetochore-produced MCC

(2018) Dong Hyun Kim et al.   Nature Communications

Actinin-1 and actinin-4 play essential but distinct roles in invadopodia formation by carcinoma cells

(2017) Hideki Yamaguchi et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells

(2017) Neng Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Global trends and predictions in hepatocellular carcinoma mortality

(2017) Paola Bertuccio et al.   JOURNAL OF HEPATOLOGY

α-Actinin-4 promotes metastasis in gastric cancer

(2017) Xin Liu et al.   LABORATORY INVESTIGATION

The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma

(2017) Ronan Le Moigne et al.   MOLECULAR CANCER THERAPEUTICS

MicroRNA therapeutics: towards a new era for the management of cancer and other diseases

(2017) Rajesha Rupaimoole et al.   NATURE REVIEWS DRUG DISCOVERY

TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma

(2017) Yi Tao et al.   Oncotarget

MicroRNA-192-5p Promote the Proliferation and Metastasis of Hepatocellular Carcinoma Cell by Targeting SEMA3A

(2017) Li Yan-Chun et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

VCP inhibitors induce endoplasmic reticulum stress, cause cell cycle arrest, trigger caspase-mediated cell death and synergistically kill ovarian cancer cells in combination with Salubrinal

(2016) Prabhakar Bastola et al.   Molecular Oncology

α-Actinin-4 induces the epithelial-to-mesenchymal transition and tumorigenesis via regulation of Snail expression and β-catenin stabilization in cervical cancer

(2016) H-T An et al.   ONCOGENE

TRIP13 is expressed in colorectal cancer and promotes cancer cell invasion

(2016) Kenji Kurita et al.   Oncology Letters

Ubiquitin-specific protease 7 accelerates p14ARFdegradation by deubiquitinating thyroid hormone receptor-interacting protein 12 and promotes hepatocellular carcinoma progression

(2015) Jia-Bin Cai et al.   HEPATOLOGY

Emerging trends in hepatocellular carcinoma incidence and mortality

(2014) Basile Njei et al.   HEPATOLOGY

TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer

(2014) Rajat Banerjee et al.   Nature Communications

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

(2013) Paola Magnaghi et al.   Nature Chemical Biology

Identification of markers of prostate cancer progression using candidate gene expression

(2011) S E T Larkin et al.   BRITISH JOURNAL OF CANCER

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS