Direct inhibition of ACTN4 by ellagic acid limits breast cancer metastasis via regulation of β-catenin stabilization in cancer stem cells

Curcumin and Ellagic acid synergistically induce ROS generation, DNA damage, p53 accumulation and apoptosis in HeLa cervical carcinoma cells

(2016) Devbrat Kumar et al.   BIOMEDICINE & PHARMACOTHERAPY

Evaluating the effects of ellagic acid on pSTAT3, pAKT, and pERK1/2 signaling pathways in prostate cancer PC3 cells

(2016) Esfandiar Heidarian et al.   Journal of Cancer Research and Therapeutics

α-Actinin-4 induces the epithelial-to-mesenchymal transition and tumorigenesis via regulation of Snail expression and β-catenin stabilization in cervical cancer

(2016) H-T An et al.   ONCOGENE

Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy

(2016) Prasad R. Dandawate et al.   SEMINARS IN CANCER BIOLOGY

The Circadian Rhythm Gene Arntl2 Is a Metastasis Susceptibility Gene for Estrogen Receptor-Negative Breast Cancer

(2016) Ngoc-Han Ha et al.   PLoS Genetics

Cancer statistics, 2015

(2015) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The origin of breast tumor heterogeneity

(2015) A Skibinski et al.   ONCOGENE

Actin-binding protein alpha-actinin 4 (ACTN4) is a transcriptional co-activator of RelA/p65 sub-unit of NF-kB.

(2015) Vasilisa Aksenova et al.   Oncotarget

Ellagic Acid Exerts Anti-proliferation Effects via Modulation of Tgf-Β/Smad3 Signaling in MCF-7 Breast Cancer Cells

(2014) Tao Zhang et al.   Asian Pacific Journal of Cancer Prevention

Luteolin, ellagic acid and punicic acid are natural products that inhibit prostate cancer metastasis

(2014) Lei Wang et al.   CARCINOGENESIS

Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via β-catenin/ABCG2 signaling

(2014) Neng Wang et al.   CARCINOGENESIS

Chemoprevention Activity of Dipyridamole in the MMTV-PyMT Transgenic Mouse Model of Breast Cancer

(2013) C. Wang et al.   Cancer Prevention Research

Curcumin Targets Breast Cancer Stem-like Cells with Microtentacles That Persist in Mammospheres and Promote Reattachment

(2013) M. S. Charpentier et al.   CANCER RESEARCH

Cancer stem cells, a fuzzy evolving concept: A cell population or a cell property?

(2013) Aline Antoniou et al.   CELL CYCLE

Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer

(2012) Neng Wang et al.   BREAST CANCER RESEARCH AND TREATMENT

Cancer Stem Cells and Novel Targets for Antitumor Strategies

(2012) Gerald J. Prud’homme   CURRENT PHARMACEUTICAL DESIGN

Alkaloids from Pachysandra terminalis Inhibit Breast Cancer Invasion and Have Potential for Development As Antimetastasis Therapeutic Agents

(2012) Hui-Yuan Zhai et al.   JOURNAL OF NATURAL PRODUCTS

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Ellagic acid coordinately attenuates Wnt/β-catenin and NF-κB signaling pathways to induce intrinsic apoptosis in an animal model of oral oncogenesis

(2011) Prabukumar Anitha et al.   EUROPEAN JOURNAL OF NUTRITION

Breast Cancer-Initiating Cells: Insights into Novel Treatment Strategies

(2011) Guido Santilli et al.   Cancers

Direct Ubiquitination of β-Catenin by Siah-1 and Regulation by the Exchange Factor TBL1

(2010) Yoana N. Dimitrova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cancer stem cells: problems for therapy?

(2010) Malcolm R Alison et al.   JOURNAL OF PATHOLOGY

Chemical genetics screen for enhancers of rapamycin identifies a specific inhibitor of an SCF family E3 ubiquitin ligase

(2010) Mariam Aghajan et al.   NATURE BIOTECHNOLOGY

α-Actinin-4 Is Essential for Maintaining the Spreading, Motility and Contractility of Fibroblasts

(2010) Hanshuang Shao et al.   PLoS One

Breast Cancer Metastasis: Challenges and Opportunities

(2009) J. Lu et al.   CANCER RESEARCH

Actinin-4 gene amplification in ovarian cancer: a candidate oncogene associated with poor patient prognosis and tumor chemoresistance

(2009) Sohei Yamamoto et al.   MODERN PATHOLOGY

Target identification using drug affinity responsive target stability (DARTS)

(2009) B. Lomenick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Breast cancer chemoresistance: Emerging importance of cancer stem cells

(2009) Suebwong Chuthapisith et al.   SURGICAL ONCOLOGY-OXFORD

The efficacy and selectivity of tumor cell killing by Akt inhibitors are substantially increased by chloroquine

(2008) Changkun Hu et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Systemic Spread Is an Early Step in Breast Cancer

(2008) Yves Hüsemann et al.   CANCER CELL

Expression and Gene Amplification of Actinin-4 in Invasive Ductal Carcinoma of the Pancreas

(2008) S. Kikuchi et al.   CLINICAL CANCER RESEARCH