miRNA Profiling for Early Detection and Treatment of Duchenne Muscular Dystrophy

sPIF promotes myoblast differentiation and utrophin expression while inhibiting fibrosis in Duchenne muscular dystrophy via the H19/miR-675/let-7 and miR-21 pathways

(2019) Daria Morgoulis et al.   Cell Death & Disease

The role of miRNAs as biomarkers in prostate cancer

(2019) J.M. Cozar et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

AAV-based gene therapies for the muscular dystrophies

(2019) Julie M Crudele et al.   HUMAN MOLECULAR GENETICS

AAV9-mediated delivery of miR-23a reduces disease severity in Smn2B/−SMA model mice

(2019) Kevin A Kaifer et al.   HUMAN MOLECULAR GENETICS

Long-term treatment with eteplirsen in nonambulatory patients with Duchenne muscular dystrophy

(2019) Lindsay N. Alfano et al.   MEDICINE

Exons 45-55 skipping using mutation-tailored cocktails of antisense morpholinos in the DMD gene

(2019) Yusuke Echigoya et al.   MOLECULAR THERAPY

MicroRNAs as Potential Diagnostic, Prognostic, and Predictive Biomarkers for Acute Graft-versus-Host Disease

(2019) Jamshid Motaei et al.   BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

Exosomes and exosomal miRNAs from muscle-derived fibroblasts promote skeletal muscle fibrosis

(2018) Simona Zanotti et al.   MATRIX BIOLOGY

Downregulation of miRNA-29, -23 and -21 in urine of Duchenne muscular dystrophy patients

(2018) Francesco Catapano et al.   Epigenomics

miR-708-5p and miR-34c-5p are involved in nNOS regulation in dystrophic context

(2018) Marine Guilbaud et al.   Skeletal Muscle

The Role of MicroRNAs in Patients with Amyotrophic Lateral Sclerosis

(2018) Efthimios Dardiotis et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Perspective: Spectrin-Like Repeats in Dystrophin Have Unique Binding Preferences for Syntrophin Adaptors That Explain the Mystery of How nNOSμ Localizes to the Sarcolemma

(2018) Justin M. Percival   Frontiers in Physiology

Identification of Cardiomyopathy-Associated Circulating miRNA Biomarkers in Muscular Dystrophy Female Carriers Using a Complementary Cardiac Imaging and Plasma Profiling Approach

(2018) Anca Florian et al.   Frontiers in Physiology

Digital PCR quantification of miR-30c and miR-181a as serum biomarkers for Duchenne muscular dystrophy

(2017) Monica Llano-Diez et al.   NEUROMUSCULAR DISORDERS

Biomarker Potential of Extracellular miRNAs in Duchenne Muscular Dystrophy

(2017) Anna M.L. Coenen-Stass et al.   TRENDS IN MOLECULAR MEDICINE

Functional improvement of dystrophic muscle by repression of utrophin: let-7c interaction

(2017) Manoj K. Mishra et al.   PLoS One

Eteplirsen: First Global Approval

(2016) Yahiya Y. Syed   DRUGS

Distribution of miRNA expression across human tissues

(2016) Nicole Ludwig et al.   NUCLEIC ACIDS RESEARCH

The Pathogenesis and Therapy of Muscular Dystrophies

(2015) Simon Guiraud et al.   Annual Review of Genomics and Human Genetics

Opposing roles of miR-21 and miR-29 in the progression of fibrosis in Duchenne muscular dystrophy

(2015) Simona Zanotti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

miRNAs as Biomarkers in Chronic Myelogenous Leukemia

(2015) Kasuen Kotagama et al.   DRUG DEVELOPMENT RESEARCH

Intra-Amniotic rAAV-Mediated Microdystrophin Gene Transfer Improves Canine X-Linked Muscular Dystrophy and May Induce Immune Tolerance

(2015) Hiromi Hayashita-Kinoh et al.   MOLECULAR THERAPY

TNF-α-Induced microRNAs Control Dystrophin Expression in Becker Muscular Dystrophy

(2015) Alyson A. Fiorillo et al.   Cell Reports

Extracellular microRNAs are dynamic non-vesicular biomarkers of muscle turnover

(2013) Thomas C. Roberts et al.   NUCLEIC ACIDS RESEARCH

Dystromirs as Serum Biomarkers for Monitoring the Disease Severity in Duchenne Muscular Dystrophy

(2013) Irina T. Zaharieva et al.   PLoS One

Loss of miR-29 in Myoblasts Contributes to Dystrophic Muscle Pathogenesis

(2012) Lijun Wang et al.   MOLECULAR THERAPY

Building Muscle: Molecular Regulation of Myogenesis

(2012) C. F. Bentzinger et al.   Cold Spring Harbor Perspectives in Biology

miRNAs as serum biomarkers for Duchenne muscular dystrophy

(2011) Davide Cacchiarelli et al.   EMBO Molecular Medicine

miR-31 modulates dystrophin expression: new implications for Duchenne muscular dystrophy therapy

(2011) Davide Cacchiarelli et al.   EMBO REPORTS

Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector

(2011) Dawn E Bowles et al.   MOLECULAR THERAPY

Improvement of the mdx mouse dystrophic phenotype by systemic in utero AAV8 delivery of a minidystrophin gene

(2010) B M Koppanati et al.   GENE THERAPY

North Star Ambulatory Assessment, 6-minute walk test and timed items in ambulant boys with Duchenne muscular dystrophy

(2010) Elena Mazzone et al.   NEUROMUSCULAR DISORDERS

Mutational spectrum of DMD mutations in dystrophinopathy patients: application of modern diagnostic techniques to a large cohort

(2009) Kevin M. Flanigan et al.   HUMAN MUTATION

Acceleration of muscle regeneration by local injection of muscle-specific microRNAs in rat skeletal muscle injury model

(2009) Tomoyuki Nakasa et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Diagnosis and management of Duchenne muscular dystrophy, part 1: diagnosis, and pharmacological and psychosocial management

(2009) Katharine Bushby et al.   LANCET NEUROLOGY

Systemic humanminidystrophingene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice

(2008) Bing Wang et al.   JOURNAL OF ORTHOPAEDIC RESEARCH