Vamorolone, a dissociative steroidal compound, reduces collagen antibody-induced joint damage and inflammation when administered after disease onset

Phase 1 trial of vamorolone, a first-in-class steroid, shows improvements in side effects via biomarkers bridged to clinical outcomes

(2018) Eric P. Hoffman et al.   STEROIDS

Cryptic glucocorticoid receptor-binding sites pervade genomic NF-κB response elements

(2018) William H. Hudson et al.   Nature Communications

Membrane Stabilization by Modified Steroid Offers a Potential Therapy for Muscular Dystrophy Due to Dysferlin Deficit

(2018) Sen Chandra Sreetama et al.   MOLECULAR THERAPY

VBP15, a novel dissociative steroid compound, reduces NFκB-induced expression of inflammatory cytokines in vitro and symptoms of murine trinitrobenzene sulfonic acid-induced colitis

(2016) Jesse M. Damsker et al.   INFLAMMATION RESEARCH

Global, regional, and national incidence, prevalence, and years lived with disability for 310 diseases and injuries, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

(2016) Theo Vos et al.   LANCET

Glucocorticoids in Early Rheumatoid Arthritis: Are the Benefits of Joint-Sparing Effects Offset by the Adverse Effect of Osteoporosis? The Effects on Bone in the Utrecht Study and the CAMERA-II Study

(2015) Johannes W.G. Jacobs et al.   NEUROIMMUNOMODULATION

Glucocorticoids in the treatment of rheumatoid arthritis: still used after 65 years

(2014) Johannes W.J. Bijlsma et al.   Annals of the New York Academy of Sciences

VBP15, a Novel Anti-Inflammatory, is Effective at Reducing the Severity of Murine Experimental Autoimmune Encephalomyelitis

(2014) Blythe C. Dillingham et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Role of cathepsin B in regulating migration and invasion of fibroblast-like synoviocytes into inflamed tissue from patients with rheumatoid arthritis

(2014) B. Tong et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

VBP15: Preclinical characterization of a novel anti-inflammatory delta 9,11 steroid

(2013) Erica K.M. Reeves et al.   BIOORGANIC & MEDICINAL CHEMISTRY

What do we know about the safety of corticosteroids in rheumatoid arthritis?

(2013) Olivier Ethgen et al.   CURRENT MEDICAL RESEARCH AND OPINION

VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

(2013) Christopher R. Heier et al.   EMBO Molecular Medicine

VBP15, a Glucocorticoid Analogue, Is Effective at Reducing Allergic Lung Inflammation in Mice

(2013) Jesse M. Damsker et al.   PLoS One

Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency

(2012) Duygu B. Bas et al.   ARTHRITIS AND RHEUMATISM

The multiple facets of glucocorticoid action in rheumatoid arthritis

(2012) Ulrike Baschant et al.   Nature Reviews Rheumatology

Developing an effective treatment algorithm for rheumatoid arthritis

(2012) E. C. Keystone et al.   RHEUMATOLOGY

Non-invasive Optical Imaging of Muscle Pathology in mdx Mice Using Cathepsin Caged Near-Infrared Imaging

(2010) Andreas R. Baudy et al.   MOLECULAR IMAGING AND BIOLOGY