VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

VBP15: Preclinical characterization of a novel anti-inflammatory delta 9,11 steroid

(2013) Erica K.M. Reeves et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Use of Quantitative Membrane Proteomics Identifies a Novel Role of Mitochondria in Healing Injured Muscles

(2012) Nimisha Sharma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A call for transparent reporting to optimize the predictive value of preclinical research

(2012) Story C. Landis et al.   NATURE

Hsp72 preserves muscle function and slows progression of severe muscular dystrophy

(2012) Stefan M. Gehrig et al.   NATURE

Glucocorticoid-Treated Mice Are an Inappropriate Positive Control for Long-Term Preclinical Studies in the mdx Mouse

(2012) Arpana Sali et al.   PLoS One

A Molecular Bandage for Diseased Muscle

(2012) D. J. Burkin et al.   Science Translational Medicine

Recombinant MG53 Protein Modulates Therapeutic Cell Membrane Repair in Treatment of Muscular Dystrophy

(2012) N. Weisleder et al.   Science Translational Medicine

Restoring Dystrophin Expression in Duchenne Muscular Dystrophy Muscle

(2011) Eric P. Hoffman et al.   AMERICAN JOURNAL OF PATHOLOGY

Growing muscle has different sarcolemmal properties from adult muscle: A proposal with scientific and clinical implications

(2011) Miranda D. Grounds et al.   BIOESSAYS

Membrane Sealant Poloxamer P188 Protects Against Isoproterenol Induced Cardiomyopathy in Dystrophin Deficient Mice

(2011) Christopher F Spurney et al.   BMC Cardiovascular Disorders

Improvement of cardiac contractile function by peptide-based inhibition of NF-κB in the utrophin/dystrophin-deficient murine model of muscular dystrophy

(2011) Dawn A Delfín et al.   Journal of Translational Medicine

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(2011) Jennifer Peterson et al.   MOLECULAR MEDICINE

Enhancing translation: Guidelines for standard pre-clinical experiments in mdx mice

(2011) Raffaella Willmann et al.   NEUROMUSCULAR DISORDERS

Promotion of plasma membrane repair by vitamin E

(2011) Amber C. Howard et al.   Nature Communications

Chronic administration of membrane sealant prevents severe cardiac injury and ventricular dilatation in dystrophic dogs

(2010) DeWayne Townsend et al.   JOURNAL OF CLINICAL INVESTIGATION

Non-invasive Optical Imaging of Muscle Pathology in mdx Mice Using Cathepsin Caged Near-Infrared Imaging

(2010) Andreas R. Baudy et al.   MOLECULAR IMAGING AND BIOLOGY

Combination of Myostatin Pathway Interference and Dystrophin Rescue Enhances Tetanic and Specific Force in Dystrophic mdx Mice

(2010) Julie Dumonceaux et al.   MOLECULAR THERAPY

In-frame Dystrophin Following Exon 51-Skipping Improves Muscle Pathology and Function in the Exon 52–Deficient mdx Mouse

(2010) Yoshitsugu Aoki et al.   MOLECULAR THERAPY

Dysferlin Deficiency and the Development of Cardiomyopathy in a Mouse Model of Limb-Girdle Muscular Dystrophy 2B

(2009) Thomas H. Chase et al.   AMERICAN JOURNAL OF PATHOLOGY

Contrasting effects of steroids and angiotensin-converting-enzyme inhibitors in a mouse model of dystrophin-deficient cardiomyopathy

(2009) Ralf Bauer et al.   EUROPEAN JOURNAL OF HEART FAILURE

A robust in vitro screening assay to identify NF-κB inhibitors for inflammatory muscle diseases

(2009) Andreas R. Baudy et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Prevention of Dystrophic Pathology in Severely Affected Dystrophin/Utrophin-deficient Mice by Morpholino-oligomer-mediated Exon-skipping

(2009) Aurélie Goyenvalle et al.   MOLECULAR THERAPY

Preclinical drug trials in themdxmouse: Assessment of reliable and sensitive outcome measures

(2009) Christopher F. Spurney et al.   MUSCLE & NERVE

Developing standard procedures for murine and canine efficacy studies of DMD therapeutics: report of two expert workshops on “Pre-clinical testing for Duchenne dystrophy”: Washington DC, October 27th–28th 2007 and Zürich, June 30th-July 1st 2008

(2009) Kanneboyina Nagaraju et al.   NEUROMUSCULAR DISORDERS

Mammalian animal models for Duchenne muscular dystrophy

(2009) Raffaella Willmann et al.   NEUROMUSCULAR DISORDERS

DNA Binding Site Sequence Directs Glucocorticoid Receptor Structure and Activity

(2009) S. H. Meijsing et al.   SCIENCE

Disodium cromoglycate protects dystrophin-deficient muscle fibers from leakiness

(2007) Maria Julia Marques et al.   MUSCLE & NERVE