Molecular basis for GIGYF–Me31B complex assembly in 4EHP-mediated translational repression

GIGYF1/2-Driven Cooperation between ZNF598 and TTP in Posttranscriptional Regulation of Inflammatory Signaling

(2019) Maxim A.X. Tollenaere et al.   Cell Reports

Direct role for the Drosophila GIGYF protein in 4EHP-mediated mRNA repression

(2019) Vincenzo Ruscica et al.   NUCLEIC ACIDS RESEARCH

Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes

(2018) Tobias Brandmann et al.   EMBO JOURNAL

4EHP-independent repression of endogenous mRNAs by the RNA-binding protein GIGYF2

(2018) Cinthia C Amaya Ramirez et al.   NUCLEIC ACIDS RESEARCH

ZNF598 Is a Quality Control Sensor of Collided Ribosomes

(2018) Szymon Juszkiewicz et al.   MOLECULAR CELL

GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression

(2017) Daniel Peter et al.   GENES & DEVELOPMENT

ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality Control Function by Mediating Regulatory 40S Ribosomal Ubiquitylation

(2017) Elayanambi Sundaramoorthy et al.   MOLECULAR CELL

Cap-binding protein 4EHP effects translation silencing by microRNAs

(2017) Clément Chapat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs

(2017) Aitor Garzia et al.   Nature Communications

Split-BioID a conditional proteomics approach to monitor the composition of spatiotemporally defined protein complexes

(2017) Isabel Myriam Schopp et al.   Nature Communications

DDX6 Represses Aberrant Activation of Interferon-Stimulated Genes

(2017) Jennifer H. Lumb et al.   Cell Reports

The DEAD-Box Protein Dhh1p Couples mRNA Decay and Translation by Monitoring Codon Optimality

(2016) Aditya Radhakrishnan et al.   CELL

Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements

(2016) Rui Fu et al.   RNA

The conformational plasticity of eukaryotic RNA-dependent ATPases

(2015) Sevim Ozgur et al.   FEBS Journal

Mextli proteins use both canonical bipartite and novel tripartite binding modes to form eIF4E complexes that display differential sensitivity to 4E-BP regulation

(2015) Daniel Peter et al.   GENES & DEVELOPMENT

Molecular Architecture of 4E-BP Translational Inhibitors Bound to eIF4E

(2015) Daniel Peter et al.   MOLECULAR CELL

DDX6 Orchestrates Mammalian Progenitor Function through the mRNA Degradation and Translation Pathways

(2015) Ying Wang et al.   MOLECULAR CELL

Structure of a Human 4E-T/DDX6/CNOT1 Complex Reveals the Different Interplay of DDX6-Binding Proteins with the CCR4-NOT Complex

(2015) Sevim Ozgur et al.   Cell Reports

A DDX6-CNOT1 Complex and W-Binding Pockets in CNOT9 Reveal Direct Links between miRNA Target Recognition and Silencing

(2014) Ying Chen et al.   MOLECULAR CELL

Structural and Biochemical Insights to the Role of the CCR4-NOT Complex and DDX6 ATPase in MicroRNA Repression

(2014) Hansruedi Mathys et al.   MOLECULAR CELL

4E-BPs require non-canonical 4E-binding motifs and a lateral surface of eIF4E to repress translation

(2014) Cátia Igreja et al.   Nature Communications

DDX6 and its orthologs as modulators of cellular and viral RNA expression

(2014) Dirk H. Ostareck et al.   Wiley Interdisciplinary Reviews-RNA

The role of disordered protein regions in the assembly of decapping complexes and RNP granules

(2013) S. Jonas et al.   GENES & DEVELOPMENT

Structural basis for the recruitment of the human CCR4–NOT deadenylase complex by tristetraprolin

(2013) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Human 4E-T represses translation of bound mRNAs and enhances microRNA-mediated silencing

(2013) A. Kamenska et al.   NUCLEIC ACIDS RESEARCH

Structural analysis of the yeast Dhh1–Pat1 complex reveals how Dhh1 engages Pat1, Edc3 and RNA in mutually exclusive interactions

(2013) Humayun Sharif et al.   NUCLEIC ACIDS RESEARCH

A Novel 4EHP-GIGYF2 Translational Repressor Complex Is Essential for Mammalian Development

(2012) M. Morita et al.   MOLECULAR AND CELLULAR BIOLOGY

Translational control in cellular and developmental processes

(2012) Jian Kong et al.   NATURE REVIEWS GENETICS

AU-Rich-Element-Dependent Translation Repression Requires the Cooperation of Tristetraprolin and RCK/P54

(2011) M.-Y. Qi et al.   MOLECULAR AND CELLULAR BIOLOGY

Conserved β-Hairpin Recognition by the GYF Domains of Smy2 and GIGYF2 in mRNA Surveillance and Vesicular Transport Complexes

(2010) Miriam-Rose Ash et al.   STRUCTURE

Structural Basis for the Mutually Exclusive Anchoring of P Body Components EDC3 and Tral to the DEAD Box Protein DDX6/Me31B

(2009) Felix Tritschler et al.   MOLECULAR CELL

Cytoplasmic Prep1 Interacts with 4EHP Inhibiting Hoxb4 Translation

(2009) J. Carlos Villaescusa et al.   PLoS One

Similar Modes of Interaction Enable Trailer Hitch and EDC3 To Associate with DCP1 and Me31B in Distinct Protein Complexes

(2008) F. Tritschler et al.   MOLECULAR AND CELLULAR BIOLOGY