From and to the Golgi – defining the Wilson disease protein road map

ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis

(2019) Vinit Shanbhag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pluripotent stem cell-derived bile canaliculi-forming hepatocytes to study genetic liver diseases involving hepatocyte polarity

(2019) Arend W. Overeem et al.   JOURNAL OF HEPATOLOGY

Ratiometric two-photon microscopy reveals attomolar copper buffering in normal and Menkes mutant cells

(2019) M. Thomas Morgan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trafficking mechanisms of P-type ATPase copper transporters

(2019) Cortnie Hartwig et al.   CURRENT OPINION IN CELL BIOLOGY

The Function of ATPase Copper Transporter ATP7B in Intestine

(2018) Hannah Pierson et al.   GASTROENTEROLOGY

Characterization of the most frequent ATP7B mutation causing Wilson disease in hepatocytes from patient induced pluripotent stem cells

(2018) Silvia Parisi et al.   Scientific Reports

ATP7A and ATP7B copper transporters have distinct functions in the regulation of neuronal dopamine-β-hydroxylase

(2018) Katharina Schmidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The interactome of the copper transporter ATP7A belongs to a network of neurodevelopmental and neurodegeneration factors

(2017) Heather S Comstra et al.   eLife

A Role for The ATP7A Copper Transporter in Tumorigenesis and Cisplatin Resistance

(2017) Sha Zhu et al.   Journal of Cancer

Myosin Vb mediates Cu+export in polarized hepatocytes

(2016) Arnab Gupta et al.   JOURNAL OF CELL SCIENCE

Basolateral sorting and transcytosis define the Cu+-regulated translocation of ATP7B to the bile canaliculus

(2016) Vasiliki Lalioti et al.   JOURNAL OF CELL SCIENCE

The emerging role of lysosomes in copper homeostasis

(2016) Elena V. Polishchuk et al.   Metallomics

Functional analysis and drug response to zinc and D-penicillamine in stableATP7Bmutant hepatic cell lines

(2016) Gursimran Chandhok et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Synthetic fluorescent probes for studying copper in biological systems

(2015) Joseph A. Cotruvo et al.   CHEMICAL SOCIETY REVIEWS

Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor

(2015) Avanti Gokhale et al.   HUMAN MOLECULAR GENETICS

COMMD1 is linked to the WASH complex and regulates endosomal trafficking of the copper transporter ATP7A

(2015) Christine A. Phillips-Krawczak et al.   MOLECULAR BIOLOGY OF THE CELL

Polarized sorting of the copper transporter ATP7B in neurons mediated by recognition of a dileucine signal by AP-1

(2015) Shweta Jain et al.   MOLECULAR BIOLOGY OF THE CELL

Wilson Disease Protein ATP7B Utilizes Lysosomal Exocytosis to Maintain Copper Homeostasis

(2014) Elena V. Polishchuk et al.   DEVELOPMENTAL CELL

Adaptor proteins involved in polarized sorting

(2014) Juan S. Bonifacino   JOURNAL OF CELL BIOLOGY

DKWSLLL, a Versatile DXXXLL-Type Signal with Distinct Roles in the Cu+-Regulated Trafficking of ATP7B

(2014) Vasiliki Lalioti et al.   TRAFFIC

Copper Directs ATP7B to the Apical Domain of Hepatic Cells via Basolateral Endosomes

(2014) Lydia K. Nyasae et al.   TRAFFIC

MEDNIK syndrome: a novel defect of copper metabolism treatable by zinc acetate therapy

(2013) Diego Martinelli et al.   BRAIN

Golgi in copper homeostasis: a view from the membrane trafficking field

(2013) Roman Polishchuk et al.   HISTOCHEMISTRY AND CELL BIOLOGY

An Extended Proteome Map of the Lysosomal Membrane Reveals Novel Potential Transporters

(2013) Agnès Chapel et al.   MOLECULAR & CELLULAR PROTEOMICS

The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky–Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIα

(2013) P. V. Ryder et al.   MOLECULAR BIOLOGY OF THE CELL

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

(2013) Florian Steinberg et al.   NATURE CELL BIOLOGY

Charting the travels of copper in eukaryotes from yeast to mammals

(2012) Tracy Nevitt et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Distinct and Overlapping Roles for AP-1 and GGAs Revealed by the “Knocksideways” System

(2012) Jennifer Hirst et al.   CURRENT BIOLOGY

Advances in the Understanding of Mammalian Copper Transporters

(2012) Yanfang Wang et al.   Advances in Nutrition

Critical roles for the COOH terminus of the Cu-ATPase ATP7B in protein stability, trans-Golgi network retention, copper sensing, and retrograde trafficking

(2011) L. Braiterman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Human copper transporters: mechanism, role in human diseases and therapeutic potential

(2009) Arnab Gupta et al.   Future Medicinal Chemistry

Apical targeting and Golgi retention signals reside within a 9-amino acid sequence in the copper-ATPase, ATP7B

(2008) Lelita Braiterman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Sorting of lysosomal proteins

(2008) Thomas Braulke et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH