Cyclin F‐dependent degradation of E2F7 is critical for DNA repair and G2‐phase progression

Cyclin F Controls Cell-Cycle Transcriptional Outputs by Directing the Degradation of the Three Activator E2Fs

(2019) Linda Clijsters et al.   MOLECULAR CELL

Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation

(2019) Maria C. Cuitiño et al.   Cell Reports

Chk1 and 14‐3‐3 proteins inhibit atypical E2Fs to prevent a permanent cell cycle arrest

(2018) Ruixue Yuan et al.   EMBO JOURNAL

An E2F7-dependent transcriptional program modulates DNA damage repair and genomic stability

(2018) Jone Mitxelena et al.   NUCLEIC ACIDS RESEARCH

Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells

(2018) Kristen E Clements et al.   NUCLEIC ACIDS RESEARCH

The E3 Ubiquitin Ligase SCF(Cyclin F) Transmits AKT Signaling to the Cell-Cycle Machinery

(2017) Rajarshi Choudhury et al.   Cell Reports

Feedback regulation between atypical E2Fs and APC/CCdh1coordinates cell cycle progression

(2016) Michiel Boekhout et al.   EMBO REPORTS

E2f8 mediates tumor suppression in postnatal liver development

(2016) Lindsey N. Kent et al.   JOURNAL OF CLINICAL INVESTIGATION

Cyclin F-Mediated Degradation of SLBP Limits H2A.X Accumulation and Apoptosis upon Genotoxic Stress in G2

(2016) John F. Dankert et al.   MOLECULAR CELL

Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer

(2016) I Thurlings et al.   ONCOGENE

SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication

(2016) David Walter et al.   Nature Communications

APC/C and SCF cyclin F Constitute a Reciprocal Feedback Circuit Controlling S-Phase Entry

(2016) Rajarshi Choudhury et al.   Cell Reports

CRISPR/Cas9-Mediated Genome Editing of Herpesviruses Limits Productive and Latent Infections

(2016) Ferdy R. van Diemen et al.   PLoS Pathogens

Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control

(2015) Ditte Kjærsgaard Klein et al.   Nature Communications

Single cell resolution in vivo imaging of DNA damage following PARP inhibition

(2015) Katherine S. Yang et al.   Scientific Reports

βTrCP controls the lysosome-mediated degradation of CDK1, whose accumulation correlates with tumor malignancy

(2015) Joaquín Herrero-Ruiz et al.   Oncotarget

Hypermutability and error catastrophe due to defects in ribonucleotide reductase

(2013) D. Ahluwalia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cyclin F-Mediated Degradation of Ribonucleotide Reductase M2 Controls Genome Integrity and DNA Repair

(2012) Vincenzo D'Angiolella et al.   CELL

The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence

(2012) O. Aksoy et al.   GENES & DEVELOPMENT

A cyclin without cyclin-dependent kinases: cyclin F controls genome stability through ubiquitin-mediated proteolysis

(2012) Vincenzo D’Angiolella et al.   TRENDS IN CELL BIOLOGY

E2F7 represses a network of oscillating cell cycle genes to control S-phase progression

(2011) Bart Westendorp et al.   NUCLEIC ACIDS RESEARCH

SCFCyclin F controls centrosome homeostasis and mitotic fidelity through CP110 degradation

(2010) Vincenzo D’Angiolella et al.   NATURE

Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools

(2010) D. Kumar et al.   NUCLEIC ACIDS RESEARCH

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

Broad Overexpression of Ribonucleotide Reductase Genes in Mice Specifically Induces Lung Neoplasms

(2008) X. Xu et al.   CANCER RESEARCH

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

DNA-damage response control of E2F7 and E2F8

(2008) L Panagiotis Zalmas et al.   EMBO REPORTS