SCFCyclin F-dependent degradation of CDC6 suppresses DNA re-replication

Cyclin F suppresses B-Myb activity to promote cell cycle checkpoint control

(2015) Ditte Kjærsgaard Klein et al.   Nature Communications

DNA Replication and Oncogene-Induced Replicative Stress

(2014) Stephanie A. Hills et al.   CURRENT BIOLOGY

Destabilization of CDC6 upon DNA damage is dependent on neddylation but independent of Cullin E3 ligases

(2013) Chia Yee Tan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Cyclin F-Mediated Degradation of Ribonucleotide Reductase M2 Controls Genome Integrity and DNA Repair

(2012) Vincenzo D'Angiolella et al.   CELL

Phosphorylation of ORC2 Protein Dissociates Origin Recognition Complex from Chromatin and Replication Origins

(2012) Kyung Yong Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Re-replication induced by geminin depletion occurs from G2 and is enhanced by checkpoint activation

(2012) K. Klotz-Noack et al.   JOURNAL OF CELL SCIENCE

Global Identification of Modular Cullin-RING Ligase Substrates

(2011) Michael J. Emanuele et al.   CELL

MCM2-7 Form Double Hexamers at Licensed Origins inXenopusEgg Extract

(2011) Agnieszka Gambus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NEDD8-Targeting Drug MLN4924 Elicits DNA Rereplication by Stabilizing Cdt1 in S Phase, Triggering Checkpoint Activation, Apoptosis, and Senescence in Cancer Cells

(2010) J. J. Lin et al.   CANCER RESEARCH

Replication licensing and the DNA damage checkpoint

(2010) Jeanette Gowen Cook   Frontiers in Bioscience-Landmark

Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS Proteins

(2010) Ivar Ilves et al.   MOLECULAR CELL

SCFCyclin F controls centrosome homeostasis and mitotic fidelity through CP110 degradation

(2010) Vincenzo D’Angiolella et al.   NATURE

Loss of DNA Replication Control Is a Potent Inducer of Gene Amplification

(2010) B. M. Green et al.   SCIENCE

Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing

(2009) Dirk Remus et al.   CELL

An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

(2009) Teresa A. Soucy et al.   NATURE

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

(2009) C. Evrin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA