Fenofibrate increases very-long-chain sphingolipids and improves blood glucose homeostasis in NOD mice

Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point

(2018) Rayner Rodriguez-Diaz et al.   Cell Metabolism

Loss of IDO1 Expression From Human Pancreatic β-Cells Precedes Their Destruction During the Development of Type 1 Diabetes

(2018) Florence Anquetil et al.   DIABETES

Abnormal islet sphingolipid metabolism in type 1 diabetes

(2018) Laurits J. Holm et al.   DIABETOLOGIA

Age-Dependent Changes to Sphingolipid Balance in the Human Hippocampus are Gender-Specific and May Sensitize to Neurodegeneration

(2018) Timothy A. Couttas et al.   JOURNAL OF ALZHEIMERS DISEASE

Metabolomics and Lipidomics Study of Mouse Models of Type 1 Diabetes Highlights Divergent Metabolism in Purine and Tryptophan Metabolism Prior to Disease Onset

(2018) Steven A. Murfitt et al.   JOURNAL OF PROTEOME RESEARCH

L-serine supplementation lowers diabetes incidence and improves blood glucose homeostasis in NOD mice

(2018) Laurits J. Holm et al.   PLoS One

Type II NKT Cells: An Elusive Population With Immunoregulatory Properties

(2018) Avadhesh Kumar Singh et al.   Frontiers in Immunology

Therapeutic targeting of diabetic retinal neuropathy as a strategy in preventing diabetic retinopathy

(2016) Gabriela de Moraes et al.   CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY

Human Type 1 Diabetes Is Characterized by an Early, Marked, Sustained, and Islet-Selective Loss of Sympathetic Nerves

(2016) Thomas O. Mundinger et al.   DIABETES

Sphingolipids and phospholipids in insulin resistance and related metabolic disorders

(2016) Peter J. Meikle et al.   Nature Reviews Endocrinology

Human acid sphingomyelinase structures provide insight to molecular basis of Niemann–Pick disease

(2016) Yan-Feng Zhou et al.   Nature Communications

Sulfatide Preserves Insulin Crystals Not by Being Integrated in the Lattice but by Stabilizing Their Surface

(2016) Karsten Buschard et al.   Journal of Diabetes Research

The Role of 3-O-Sulfogalactosylceramide, Sulfatide, in the Lateral Organization of Myelin Membrane

(2015) Sara Grassi et al.   NEUROCHEMICAL RESEARCH

Glycemic Variability: How Do We Measure It and Why Is It Important?

(2015) Sunghwan Suh et al.   Diabetes & Metabolism Journal

CerS2 Haploinsufficiency Inhibits β-Oxidation and Confers Susceptibility to Diet-Induced Steatohepatitis and Insulin Resistance

(2014) Suryaprakash Raichur et al.   Cell Metabolism

Neural regulation of pancreatic islet cell mass and function

(2014) B. Thorens   DIABETES OBESITY & METABOLISM

Non-neural tyrosine hydroxylase, via modulation of endocrine pancreatic precursors, is required for normal development of beta cells in the mouse pancreas

(2014) Patricia Vázquez et al.   DIABETOLOGIA

Sphingolipid metabolites in inflammatory disease

(2014) Michael Maceyka et al.   NATURE

Sphingolipid Metabolism and Interorganellar Transport: Localization of Sphingolipid Enzymes and Lipid Transfer Proteins

(2014) Toshiyuki Yamaji et al.   TRAFFIC

Phospholipid Synthesis and Transport in Mammalian Cells

(2014) Jean E. Vance   TRAFFIC

Ablation of Ceramide Synthase 2 Causes Chronic Oxidative Stress Due to Disruption of the Mitochondrial Respiratory Chain

(2013) Hila Zigdon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sympathetic Innervation during Development Is Necessary for Pancreatic Islet Architecture and Functional Maturation

(2013) Philip Borden et al.   Cell Reports

Early Loss of the Glucagon Response to Hypoglycemia in Adolescents With Type 1 Diabetes

(2012) A. Siafarikas et al.   DIABETES CARE

Ablation of very long acyl chain sphingolipids causes hepatic insulin resistance in mice due to altered detergent-resistant membranes

(2012) Joo-Won Park et al.   HEPATOLOGY

NKT Cells Stimulated by Long Fatty Acyl Chain Sulfatides Significantly Reduces the Incidence of Type 1 Diabetes in Nonobese Diabetic Mice

(2012) Lakshmimathy Subramanian et al.   PLoS One

Noninvasive in vivo model demonstrating the effects of autonomic innervation on pancreatic islet function

(2012) R. Rodriguez-Diaz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liver Hypertrophy

(2012) A. P. Hall et al.   TOXICOLOGIC PATHOLOGY

Roles of ceramide and sphingolipids in pancreatic β-cell function and dysfunction

(2012) Ebru Boslem et al.   Islets

Innervation Patterns of Autonomic Axons in the Human Endocrine Pancreas

(2011) Rayner Rodriguez-Diaz et al.   Cell Metabolism

Synthetic isoforms of endogenous sulfatides differently modulate indoleamine 2,3-dioxygenase in antigen presenting cells

(2011) Emanuela Altomare et al.   LIFE SCIENCES

Membrane lipidome of an epithelial cell line

(2011) Julio L. Sampaio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chain length-specific properties of ceramides

(2011) Sabine Grösch et al.   PROGRESS IN LIPID RESEARCH

Metabolic Regulation in Progression to Autoimmune Diabetes

(2011) Marko Sysi-Aho et al.   PLoS Computational Biology

Lysophosphatidylcholine Containing Docosahexaenoic Acid at the sn-1 Position is Anti-inflammatory

(2010) Long Shuang Huang et al.   LIPIDS

Loss of islet sympathetic nerves and impairment of glucagon secretion in the NOD mouse: relationship to invasive insulitis

(2009) G. J. Taborsky et al.   DIABETOLOGIA

Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

(2009) C. S. Ejsing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes

(2008) Matej Orešič et al.   JOURNAL OF EXPERIMENTAL MEDICINE