Blocking Notch signal pathway suppresses the activation of neurotoxic A1 astrocytes after spinal cord injury

Inhibition of Stat3‐mediated astrogliosis ameliorates pathology in an Alzheimer's disease model

(2019) Nicole Reichenbach et al.   EMBO Molecular Medicine

The origin, fate, and contribution of macrophages to spinal cord injury pathology

(2019) Lindsay M. Milich et al.   ACTA NEUROPATHOLOGICA

Role of Jagged1/ STAT 3 signalling in platinum‐resistant ovarian cancer

(2019) Jiang Yang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Thymosin beta 4 attenuates oxidative stress-induced injury of spinal cord-derived neural stem/progenitor cells through the TLR4/MyD88 pathway

(2019) Hongwei Li et al.   GENE

Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury

(2018) Hong-Mei Zhang et al.   PLoS One

MFG-E8 reverses microglial-induced neurotoxic astrocyte (A1) via NF-κB and PI3K-Akt pathways

(2018) Xiaotian Xu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Neuronal Polarity: MAP2 Shifts Secretory Vesicles into High Gear for Long-Haul Transport down the Axon

(2017) Luís F. Ribeiro et al.   NEURON

Notch Signaling in Development, Tissue Homeostasis, and Disease

(2017) Chris Siebel et al.   PHYSIOLOGICAL REVIEWS

Traumatic spinal cord injury

(2017) Christopher S. Ahuja et al.   Nature Reviews Disease Primers

Inhibition of Notch signaling pathway attenuates sympathetic hyperinnervation together with the augmentation of M2 macrophages in rats post-myocardial infarction

(2016) Jie Yin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

SnapShot: Astrocytes in Health and Disease

(2015) Shane Liddelow et al.   CELL

The JAK/STAT3 Pathway Is a Common Inducer of Astrocyte Reactivity in Alzheimer's and Huntington's Diseases

(2015) L. Ben Haim et al.   JOURNAL OF NEUROSCIENCE

Synergistic association of Notch and NFκB signaling and role of Notch signaling in modulating epithelial to mesenchymal transition in colorectal adenocarcinoma

(2014) Natarajan Gopalakrishnan et al.   BIOCHIMIE

Incidence of traumatic spinal cord injury worldwide: a systematic review

(2014) Seyed Behzad Jazayeri et al.   EUROPEAN SPINE JOURNAL

Non-mammalian model systems for studying neuro-immune interactions after spinal cord injury

(2014) Ona Bloom   EXPERIMENTAL NEUROLOGY

Astrocytic TGF-  Signaling Limits Inflammation and Reduces Neuronal Damage during Central Nervous System Toxoplasma Infection

(2014) E. Cekanaviciute et al.   JOURNAL OF IMMUNOLOGY

‘Hit & Run’ Model of Closed-Skull Traumatic Brain Injury (TBI) Reveals Complex Patterns of Post-Traumatic AQP4 Dysregulation

(2013) Zeguang Ren et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Emerging roles of astrocytes in neural circuit development

(2013) Laura E. Clarke et al.   NATURE REVIEWS NEUROSCIENCE

Notch-1 Signaling Regulates Microglia Activation via NF-κB Pathway after Hypoxic Exposure In Vivo and In Vitro

(2013) Linli Yao et al.   PLoS One

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Evidence that  -Secretase-Mediated Notch Signaling Induces Neuronal Cell Death via the Nuclear Factor- B-Bcl-2-Interacting Mediator of Cell Death Pathway in Ischemic Stroke

(2011) T. V. Arumugam et al.   MOLECULAR PHARMACOLOGY

Notch Activation Enhances the Microglia-Mediated Inflammatory Response Associated With Focal Cerebral Ischemia

(2011) Zelan Wei et al.   STROKE

Proliferating Reactive Astrocytes Are Regulated by Notch-1 in the Peri-Infarct Area After Stroke

(2011) Issei S. Shimada et al.   STROKE

Autoamplification of Notch Signaling in Macrophages by TLR-Induced and RBP-J-Dependent Induction of Jagged1

(2010) J. Foldi et al.   JOURNAL OF IMMUNOLOGY

Guidance Molecules in Axon Regeneration

(2010) R. J. Giger et al.   Cold Spring Harbor Perspectives in Biology

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

RBP-J promotes neuronal differentiation and inhibits oligodendroglial development in adult neurogenesis

(2009) Motoaki Fujimoto et al.   DEVELOPMENTAL BIOLOGY

Molecular dissection of reactive astrogliosis and glial scar formation

(2009) Michael V. Sofroniew   TRENDS IN NEUROSCIENCES

Expression of Notch-1 receptor and its ligands Jagged-1 and Delta-1 in amoeboid microglia in postnatal rat brain and murine BV-2 cells

(2008) Qiong Cao et al.   GLIA

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

(2008) J. E. Herrmann et al.   JOURNAL OF NEUROSCIENCE