Inhibition of Notch signaling pathway attenuates sympathetic hyperinnervation together with the augmentation of M2 macrophages in rats post-myocardial infarction

Activation in M1 but not M2 Macrophages Contributes to Cardiac Remodeling after Myocardial Infarction in Rats: a Critical Role of the Calcium Sensing Receptor/NRLP3 Inflammasome

(2015) Wenxiu Liu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cardiac macrophages and their role in ischaemic heart disease

(2014) Stefan Frantz et al.   CARDIOVASCULAR RESEARCH

Ly-6C high Monocytes Depend on Nr4a1 to Balance Both Inflammatory and Reparative Phases in the Infarcted Myocardium

(2014) Ingo Hilgendorf et al.   CIRCULATION RESEARCH

Epigenetic Modification at Notch Responsive Promoters Blunts Efficacy of Inducing Notch Pathway Reactivation After Myocardial Infarction

(2014) Giulia Felician et al.   CIRCULATION RESEARCH

Interleukin-13 Deficiency Aggravates Healing and Remodeling in Male Mice After Experimental Myocardial Infarction

(2014) Ulrich Hofmann et al.   Circulation-Heart Failure

Macrophages are required for neonatal heart regeneration

(2014) Arin B. Aurora et al.   JOURNAL OF CLINICAL INVESTIGATION

Caveolin-1 deletion exacerbates cardiac interstitial fibrosis by promoting M2 macrophage activation in mice after myocardial infarction

(2014) Pooja Shivshankar et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Perioperative aspirin improves neurological outcome after focal brain ischemia possibly via inhibition of Notch 1 in rat

(2014) Zhongxing Wang et al.   Journal of Neuroinflammation

Up-regulation of heme oxygenase-1 after infarct initiation reduces mortality, infarct size and left ventricular remodeling: experimental evidence and proof of concept

(2014) Claudia Kusmic et al.   Journal of Translational Medicine

Targeted NGF siRNA Delivery Attenuates Sympathetic Nerve Sprouting and Deteriorates Cardiac Dysfunction in Rats with Myocardial Infarction

(2014) Hesheng Hu et al.   PLoS One

Pharmacological Inhibitor of Notch Signaling Stabilizes the Progression of Small Abdominal Aortic Aneurysm in a Mouse Model

(2014) Jeeyun Cheng et al.   Journal of the American Heart Association

Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation

(2013) D. Kurotaki et al.   BLOOD

Expanding Role of Delta-Like 4 Mediated Notch Signaling in Cardiovascular and Metabolic Diseases

(2013) Daiju Fukuda et al.   CIRCULATION JOURNAL

Sympathetic denervation of peri-infarct myocardium requires the p75 neurotrophin receptor

(2013) Christina U. Lorentz et al.   EXPERIMENTAL NEUROLOGY

Acute and subacute IL-1β administrations differentially modulate neuroimmune and neurotrophic systems: possible implications for neuroprotection and neurodegeneration

(2013) Cai Song et al.   Journal of Neuroinflammation

Contribution of Macrophages to Enhanced Regenerative Capacity of Dorsal Root Ganglia Sensory Neurons by Conditioning Injury

(2013) M. J. Kwon et al.   JOURNAL OF NEUROSCIENCE

Transcranial amelioration of inflammation and cell death after brain injury

(2013) Theodore L. Roth et al.   NATURE

Myocardial infarction induces sympathetic hyperinnervation via a nuclear factor-κB-dependent pathway in rabbit hearts

(2013) Ye Wang et al.   NEUROSCIENCE LETTERS

Notch-1 Signaling Regulates Microglia Activation via NF-κB Pathway after Hypoxic Exposure In Vivo and In Vitro

(2013) Linli Yao et al.   PLoS One

Simvastatin attenuates sympathetic hyperinnervation to prevent atrial fibrillation during the postmyocardial infarction remodeling process

(2012) Tao Yu et al.   JOURNAL OF APPLIED PHYSIOLOGY

Notch–RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization

(2012) Haixia Xu et al.   NATURE IMMUNOLOGY

Notch1 in Bone Marrow–Derived Cells Mediates Cardiac Repair After Myocardial Infarction

(2011) Yuxin Li et al.   CIRCULATION

Differential effects of NADPH oxidase and xanthine oxidase inhibition on sympathetic reinnervation in postinfarct rat hearts

(2011) Tsung-Ming Lee et al.   FREE RADICAL BIOLOGY AND MEDICINE

Statin Attenuates Experimental Anti-Glomerular Basement Membrane Glomerulonephritis Together with the Augmentation of Alternatively Activated Macrophages

(2010) Emiko Fujita et al.   AMERICAN JOURNAL OF PATHOLOGY

Alteration of Parasympathetic/Sympathetic Ratio in the Infarcted Myocardium After Schwann Cell Transplantation Modified Electrophysiological Function of Heart: A Novel Antiarrhythmic Therapy

(2010) H. Zhang et al.   CIRCULATION

Monocytes: Protagonists of Infarct Inflammation and Repair After Myocardial Infarction

(2010) Matthias Nahrendorf et al.   CIRCULATION

Corneal myofibroblast generation from bone marrow-derived cells

(2010) Flavia L. Barbosa et al.   EXPERIMENTAL EYE RESEARCH

Notch1 Deficiency Results in Decreased Inflammation during Wound Healing and Regulates Vascular Endothelial Growth Factor Receptor-1 and Inflammatory Cytokine Expression in Macrophages

(2010) H. Hamilton Outtz et al.   JOURNAL OF IMMUNOLOGY

Comparative investigation of the left ventricular pressure-volume relationship in rat models of type 1 and type 2 diabetes mellitus

(2009) Tamás Radovits et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Macrophage depletion suppresses sympathetic hyperinnervation following myocardial infarction

(2009) Gwenaelle Wernli et al.   BASIC RESEARCH IN CARDIOLOGY

Effect of N-acetylcysteine on sympathetic hyperinnervation in post-infarcted rat hearts

(2009) T.-M. Lee et al.   CARDIOVASCULAR RESEARCH

Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1β release through pyrophosphates

(2009) Pablo Pelegrin et al.   EMBO JOURNAL

Notch1 upregulates LPS-induced macrophage activation by increasing NF-κB activity

(2009) Eva Monsalve et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Jagged1 regulates the activation of astrocytes via modulation of NFκB and JAK/STAT/SOCS pathways

(2009) Eleonora Morga et al.   GLIA

Classically and alternatively activated macrophages contribute to tissue remodelling after myocardial infarction

(2009) C. Troidl et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Dexamethasone treatment of post-MI rats attenuates sympathetic innervation of the infarct region

(2007) Viviane El-Helou et al.   JOURNAL OF APPLIED PHYSIOLOGY