Amelioration of Diabetic Mouse Nephropathy by Catalpol Correlates with Down-Regulation of Grb10 Expression and Activation of Insulin-Like Growth Factor 1 / Insulin-Like Growth Factor 1 Receptor Signaling

Interplay of oxidative, nitrosative/nitrative stress, inflammation, cell death and autophagy in diabetic cardiomyopathy

(2015) Zoltán V. Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Inhibition of insulin/IGF-1 receptor signaling protects from mitochondria-mediated kidney failure

(2015) C. Ising et al.   EMBO Molecular Medicine

Monoallelic Loss of the Imprinted Gene Grb10 Promotes Tumor Formation in Irradiated Nf1+/- Mice

(2015) Rana Mroue et al.   PLoS Genetics

Heme oxygenase-1 attenuates cadmium-induced mitochondrial-caspase 3- dependent apoptosis in human hepatoma cell line

(2015) Akeem O. Lawal et al.   BMC Pharmacology & Toxicology

Protective effect of catalpol on lipopolysaccharide-induced acute lung injury in mice

(2014) Kai Fu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Catalpol Suppresses Proliferation and Facilitates Apoptosis of OVCAR-3 Ovarian Cancer Cells through Upregulating MicroRNA-200 and Downregulating MMP-2 Expression

(2014) Na Gao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Grb10 Deletion Enhances Muscle Cell Proliferation, Differentiation and GLUT4 Plasma Membrane Translocation

(2014) Nancy Mokbel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Negative Regulation of Grb10 Interacting GYF Protein 2 on Insulin-Like Growth Factor-1 Receptor Signaling Pathway Caused Diabetic Mice Cognitive Impairment

(2014) Jing Xie et al.   PLoS One

A Central Role for GRB10 in Regulation of Islet Function in Man

(2014) Inga Prokopenko et al.   PLoS Genetics

Neuroprotective activities of catalpol against CaMKII-dependent apoptosis induced by LPS in PC12 cells

(2013) Wenna Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Growth receptor binding protein 10 inhibits glucose-stimulated insulin release from pancreatic β-cells associated with suppression of the insulin/insulin-like growth factor-1 signalling pathway

(2013) Ling Li et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Renoprotection of Danshen Injection on streptozotocin-induced diabetic rats, associated with tubular function and structure

(2013) DengKe Yin et al.   JOURNAL OF ETHNOPHARMACOLOGY

Growth Factor Receptor-Bound Protein 10-Mediated Negative Regulation of the Insulin-Like Growth Factor-1 Receptor-Activated Signalling Pathway Results in Cognitive Disorder in Diabetic Rats

(2013) L. Ma et al.   JOURNAL OF NEUROENDOCRINOLOGY

Radio-protective effect of catalpol in cultured cells and mice

(2013) C. Chen et al.   JOURNAL OF RADIATION RESEARCH

The utility of the IGF-I generation test in children with chronic kidney disease

(2013) Amira Al-Uzri et al.   PEDIATRIC NEPHROLOGY

Effect of catalpol on diabetic nephropathy in rats

(2013) Zhao Dong et al.   PHYTOMEDICINE

Disruption of Growth Factor Receptor-Binding Protein 10 in the Pancreas Enhances  -Cell Proliferation and Protects Mice From Streptozotocin-Induced  -Cell Apoptosis

(2012) J. Zhang et al.   DIABETES

Grb10 regulates the development of fiber number in skeletal muscle

(2012) Lowenna J. Holt et al.   FASEB JOURNAL

Catalpol inhibits LPS plus IFN-γ-induced inflammatory response in astrocytes primary cultures

(2012) Jing Bi et al.   TOXICOLOGY IN VITRO

Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

(2011) Y. Yu et al.   SCIENCE

Andrographolide and 14-deoxy-11,12-didehydroandrographolide from Andrographis paniculata attenuate high glucose-induced fibrosis and apoptosis in murine renal mesangeal cell lines

(2010) Meng-Jen Lee et al.   JOURNAL OF ETHNOPHARMACOLOGY

Pathologic Classification of Diabetic Nephropathy

(2010) T. W. C. Tervaert et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Grb10 interacts with Bim L and inhibits apoptosis

(2010) Zhi-qian Hu et al.   MOLECULAR BIOLOGY REPORTS

Immunity to Growth Factor Receptor-Bound Protein 10, a Signal Transduction Molecule, Inhibits the Growth of Breast Cancer in Mice

(2008) I. O-Sullivan et al.   CANCER RESEARCH