HPO-Shuffle: an associated gene prioritization strategy and its application in drug repurposing for the treatment of canine epilepsy

Species differences in metabolism of a new antiepileptic drug candidate, DSP‐0565 [2‐(2'‐fluoro[1,1'‐biphenyl]‐2‐yl)acetamide]

(2019) Masahiro Yahata et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Novel mutations and phenotypes of epilepsy-associated genes in epileptic encephalopathies

(2018) P. Zhou et al.   GENES BRAIN AND BEHAVIOR

Genome-Scale In Silico Analysis for Enhanced Production of Succinic Acid in Zymomonas mobilis

(2018) Hanifah Widiastuti et al.   Processes

OMIM.org: leveraging knowledge across phenotype–gene relationships

(2018) Joanna S Amberger et al.   NUCLEIC ACIDS RESEARCH

Tubulin β-III modulates seizure activity in epilepsy

(2017) Xin Xu et al.   JOURNAL OF PATHOLOGY

Suspected Phenobarbital-Induced Pseudolymphoma in a Dog

(2017) R. Lampe et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Pretreatment behavior and subsequent medication effects in childhood absence epilepsy

(2017) Ruth C. Shinnar et al.   NEUROLOGY

ClinVar: improving access to variant interpretations and supporting evidence

(2017) Melissa J Landrum et al.   NUCLEIC ACIDS RESEARCH

Upregulation of breast cancer resistance protein and major vault protein in drug resistant epilepsy

(2017) Aparna Banerjee Dixit et al.   SEIZURE-EUROPEAN JOURNAL OF EPILEPSY

Exploring the pathogenesis of canine epilepsy using a systems genetics method and implications for anti-epilepsy drug discovery

(2017) Ze-Jia Cui et al.   Oncotarget

Aspirin for the Primary Prevention of Cardiovascular Events: A Systematic Evidence Review for the U.S. Preventive Services Task Force

(2016) Janelle M. Guirguis-Blake et al.   ANNALS OF INTERNAL MEDICINE

Explaining the disease phenotype of intergenic SNP through predicted long range regulation

(2016) Jingqi Chen et al.   NUCLEIC ACIDS RESEARCH

Complex disease and phenotype mapping in the domestic dog

(2016) Jessica J. Hayward et al.   Nature Communications

7,8-dihydroxyflavone, a small molecular TrkB agonist, is useful for treating various BDNF-implicated human disorders

(2016) Chaoyang Liu et al.   Translational Neurodegeneration

International Veterinary Epilepsy Task Force consensus proposal: medical treatment of canine epilepsy in Europe

(2015) Sofie F.M. Bhatti et al.   BMC Veterinary Research

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes

(2015) J. Pinero et al.   Database-The Journal of Biological Databases and Curation

Second-generation PLINK: rising to the challenge of larger and richer datasets

(2015) Christopher C Chang et al.   GigaScience

A Quantitative Systems Pharmacology Perspective on Cancer Immunology

(2015) Christina Byrne-Hoffman et al.   Processes

Distinct Physiological Effects of Dopamine D4 Receptors on Prefrontal Cortical Pyramidal Neurons and Fast-Spiking Interneurons

(2014) Ping Zhong et al.   CEREBRAL CORTEX

A Hypothesis Regarding the Molecular Mechanism Underlying Dietary Soy-Induced Effects on Seizure Propensity

(2014) Cara Jean Westmark   Frontiers in Neurology

Genome wide association studies (GWAS) and common forms of human epilepsy

(2013) Russell J. Buono   EPILEPSY & BEHAVIOR

Role of the mTOR signaling pathway in epilepsy

(2013) Xiang-Fei Meng et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

The Human Phenotype Ontology project: linking molecular biology and disease through phenotype data

(2013) Sebastian Köhler et al.   NUCLEIC ACIDS RESEARCH

Inherited Epilepsy in Dogs

(2013) Kari J. Ekenstedt et al.   Topics in Companion Animal Medicine

Action of nicotine and analogs on acetylcholine receptors having mutations of transmitter-binding site residue αG153

(2012) Snehal Jadey et al.   JOURNAL OF GENERAL PHYSIOLOGY

Importazole, a Small Molecule Inhibitor of the Transport Receptor Importin-β

(2011) Jonathan F. Soderholm et al.   ACS Chemical Biology

Two-stage genome-wide association study identifies variants in CAMSAP1L1 as susceptibility loci for epilepsy in Chinese

(2011) Youling Guo et al.   HUMAN MOLECULAR GENETICS

A truncating mutation in ATP13A2 is responsible for adult-onset neuronal ceroid lipofuscinosis in Tibetan terriers

(2011) Fabiana H.G. Farias et al.   NEUROBIOLOGY OF DISEASE

GWASdb: a database for human genetic variants identified by genome-wide association studies

(2011) Mulin Jun Li et al.   NUCLEIC ACIDS RESEARCH

LGI2 Truncation Causes a Remitting Focal Epilepsy in Dogs

(2011) Eija H. Seppälä et al.   PLoS Genetics

Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study

(2010) Dalia Kasperavičiūtė et al.   BRAIN

A Missense Mutation in CanineCLN6in an Australian Shepherd with Neuronal Ceroid Lipofuscinosis

(2010) Martin L. Katz et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

A Synthetic 7,8-Dihydroxyflavone Derivative Promotes Neurogenesis and Exhibits Potent Antidepressant Effect

(2010) Xia Liu et al.   JOURNAL OF MEDICINAL CHEMISTRY

A mutation in canine PPT1 causes early onset neuronal ceroid lipofuscinosis in a Dachshund

(2010) Douglas N. Sanders et al.   MOLECULAR GENETICS AND METABOLISM

A canine Arylsulfatase G (ARSG) mutation leading to a sulfatase deficiency is associated with neuronal ceroid lipofuscinosis

(2010) M. Abitbol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

(2009) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks

(2009) Gabriela Bindea et al.   BIOINFORMATICS

WGCNA: an R package for weighted correlation network analysis

(2008) Peter Langfelder et al.   BMC BIOINFORMATICS

Gene expression analysis in absence epilepsy using a monozygotic twin design

(2008) Ingo Helbig et al.   EPILEPSIA