Recent advances in transition-metal-catalyzed incorporation of fluorine-containing groups

Recent Advances in Transition-Metal-Mediated Chelation- Assisted Sulfonylation of Unactivated C−H Bonds

(2019) Jidan Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Copper-Catalyzed Remote C(sp3 )−H Trifluoromethylation of Carboxamides and Sulfonamides

(2019) Zhonglin Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Merging Visible-Light Catalysis for the Direct Late-Stage Group 16-Trifluoromethyl Bond Formation

(2019) Clément Ghiazza et al.   CHEMISTRY-A EUROPEAN JOURNAL

The fluorination of C-H bonds: developments and perspectives

(2019) Veronique Gouverneur et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed C3−H Difluoroacetylation of Quinoxalinones with Ethyl Bromodifluoroacetate

(2019) Liping Wang et al.   ADVANCED SYNTHESIS & CATALYSIS

Synthesis of Tri- and Difluoromethoxylated Compounds by Visible-Light Photoredox Catalysis

(2019) Johnny W. Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Benzylic Fluorination of Aza-Heterocycles Induced by Single-Electron Transfer to Selectfluor

(2018) Kelley E. Danahy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Radical Revolution for Trifluoromethoxylation

(2018) Basudev Sahoo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic C−H Trifluoromethoxylation of Arenes and Heteroarenes

(2018) Weijia Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Highly Stereoselective Trifluoromethylation and Difluoroalkylation of Secondary Propargyl Sulfonates

(2018) Xing Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-Light Photocatalysis: Does It Make a Difference in Organic Synthesis?

(2018) Leyre Marzo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bulky Diamine Ligand Promotes Cross-Coupling of Difluoroalkyl Bromides by Iron Catalysis

(2018) Lun An et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Radical Trifluoromethoxylation of Arenes Triggered by a Visible-Light-Mediated N-O Redox Fragmentation

(2018) Antonio Togni et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Ruthenium(II)-Catalyzed C−H Difluoromethylation of Ketoximes: Tuning the Regioselectivity from the meta to the para Position

(2018) Chunchen Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fe(II)-Catalyzed Site-selective Functionalization of Unactivated C(sp3)-H Bonds Guided by Alkoxyl Radical

(2018) Lei Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Progress in copper-catalyzed trifluoromethylation

(2018) Guan-bao Li et al.   Beilstein Journal of Organic Chemistry

Synthesis of Alpha-trifluoromethylthio Carbonyl Compounds: A Survey of the Methods for the Direct Introduction of the SCF3 Group on to Organic Molecules

(2018) Sergio Rossi et al.   ChemCatChem

Coordinating Activation Strategy-Induced Selective C−H Trifluoromethylation of Anilines

(2018) Jun Xu et al.   ChemCatChem

Fluoroalkylation reactions in aqueous media: a review

(2018) Hai-Xia Song et al.   GREEN CHEMISTRY

Pd-Catalyzed, ortho C–H Methylation and Fluorination of Benzaldehydes Using Orthanilic Acids as Transient Directing Groups

(2018) Xiao-Yang Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids

(2018) Jacob A. Kautzky et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlling Pd(iv) reductive elimination pathways enables Pd(ii)-catalysed enantioselective C(sp3)−H fluorination

(2018) Hojoon Park et al.   Nature Chemistry

Iron-catalyzed ortho trifluoromethylation of anilines via picolinamide assisted photoinduced C–H functionalization

(2018) Chengcai Xia et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Nitrate-promoted Selective C–H Fluorination of Benzamides and Benzeneacetamides

(2018) Xing-Qian Ning et al.   ORGANIC LETTERS

Nickel-Catalyzed Direct C–H Trifluoromethylation of Free Anilines with Togni’s Reagent

(2018) Xianying Gao et al.   ORGANIC LETTERS

Site selectivities in fluorination

(2018) Syo Ishida et al.   TETRAHEDRON LETTERS

Ruthenium(II)-enabled para-selective C–H difluoromethylation of anilides and their derivatives

(2018) Chunchen Yuan et al.   Nature Communications

Visible-light photocatalytic trifluoromethylthiolation of aryldiazonium salts: conversion of amino group into trifluoromethylthiol group

(2018) Xia Zhao et al.   Organic Chemistry Frontiers

Metal-Mediated Halogen Exchange in Aryl and Vinyl Halides: A Review

(2018) Gwilherm Evano et al.   Frontiers in Chemistry

Transition-Metal (Cu, Pd, Ni)-Catalyzed Difluoroalkylation via Cross-Coupling with Difluoroalkyl Halides

(2018) Zhang Feng et al.   ACCOUNTS OF CHEMICAL RESEARCH

Selective C(sp3)-H and C(sp2)-H Fluorination of Alcohols Using Practical Auxiliaries

(2018) Yang-Jie Mao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox-Active Reagents for Photocatalytic Generation of the OCF3 Radical and (Hetero)Aryl C−H Trifluoromethoxylation

(2018) Weijia Zheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-catalysed electrophilic aromatic C–H fluorination

(2018) Kumiko Yamamoto et al.   NATURE

Radical Aromatic Trifluoromethylthiolation: Photoredox Catalysis vs. Base Mediation

(2017) Denis Koziakov et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Coupling of Acyl Chlorides with gem-Difluorinated Organozinc Reagents via Acyl Dithiocarbamates

(2017) Salavat S. Ashirbaev et al.   JOURNAL OF ORGANIC CHEMISTRY

Silver-Catalyzed Decarboxylative Trifluoromethylation of Aliphatic Carboxylic Acids

(2017) Xinqiang Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phosphovanadomolybdic acid catalyzed direct C–H trifluoromethylation of (hetero)arenes using NaSO2CF3 as the CF3 source and O2 as the terminal oxidant

(2017) Chifeng Li et al.   NEW JOURNAL OF CHEMISTRY

Nickel(II)-Catalyzed Site-Selective C–H Bond Trifluoromethylation of Arylamine in Water through a Coordinating Activation Strategy

(2017) Jun Xu et al.   ORGANIC LETTERS

A catalytic fluoride-rebound mechanism for C(sp3)-CF3bond formation

(2017) Mark D. Levin et al.   SCIENCE

Palladium-Catalyzed Synthesis of Aryl and Heteroaryl Difluoromethylated Phosphonates

(2017) Thomas Poisson et al.   SYNTHESIS-STUTTGART

Asymmetric Synthesis of Allylic Fluorides via Fluorination of Racemic Allylic Trichloroacetimidates Catalyzed by a Chiral Diene-Iridium Complex

(2017) Jason C. Mixdorf et al.   ACS Catalysis

Visible-Light Photocatalytic Decarboxylation of α,β-Unsaturated Carboxylic Acids: Facile Access to Stereoselective Difluoromethylated Styrenes in Batch and Flow

(2017) Xiao-Jing Wei et al.   ACS Catalysis

Copper-catalyzed trifluoromethylation of styrene derivatives with CF3SO2Na

(2017) Liu-Hai Wu et al.   Organic Chemistry Frontiers

The Evolution of Pd0/PdII-Catalyzed Aromatic Fluorination

(2016) Aaron C. Sather et al.   ACCOUNTS OF CHEMICAL RESEARCH

Site-Selective Tertiary Alkyl-Fluorine Bond Formation from α-Bromoamides Using a Copper/CsF Catalyst System

(2016) Takashi Nishikata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthetic Approaches to Trifluoromethoxy-Substituted Compounds

(2016) Anis Tlili et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Gold-Catalyzed Highly Selective Photoredox C(sp2 )−H Difluoroalkylation and Perfluoroalkylation of Hydrazones

(2016) Jin Xie et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Modern Transition-Metal-Catalyzed Carbon–Halogen Bond Formation

(2016) David A. Petrone et al.   CHEMICAL REVIEWS

Trifluoromethylthiolation and Trifluoromethylselenolation of α-Diazo Esters Catalyzed by Copper

(2016) Christian Matheis et al.   CHEMISTRY-A EUROPEAN JOURNAL

Visible-Light-Promoted Trifluoromethylthiolation of Styrenes by Dual Photoredox/Halide Catalysis

(2016) Roman Honeker et al.   CHEMISTRY-A EUROPEAN JOURNAL

Visible Light-Promoted Decarboxylative Di- and Trifluoromethylthiolation of Alkyl Carboxylic Acids

(2016) Lisa Candish et al.   CHEMISTRY-A EUROPEAN JOURNAL

Visible-Light-Promoted Activation of Unactivated C(sp3)–H Bonds and Their Selective Trifluoromethylthiolation

(2016) Satobhisha Mukherjee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iron-Catalyzed, Fluoroamide-Directed C–H Fluorination

(2016) Brian J. Groendyke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Quantitative Scale for the Trifluoromethylthio Cation-Donating Ability of Electrophilic Trifluoromethylthiolating Reagents

(2016) Man Li et al.   ORGANIC LETTERS

Palladium-catalyzed electrophilic C–H fluorination of arenes using oxazoline as a removable directing group

(2016) David A. Gutierrez et al.   TETRAHEDRON LETTERS

Silver(I)-catalyzed denitrative trifluoromethylation of β-nitrostyrenes with CF 3 SO 2 Na

(2016) Ping Huang et al.   TETRAHEDRON LETTERS

C–H Difluoroalkylation of Aldehyde Hydrazones with Functionalized Difluoromethyl Bromides under Copper Catalysis

(2016) Alexis Prieto et al.   ACS Catalysis

Copper-Catalyzed Trifluoromethylation of Hydrazones Leading to the Formation of Quaternary α-Trifluoromethyl Diazenes

(2016) Alexis Prieto et al.   Asian Journal of Organic Chemistry

2-Diazo-1-phenyl-2-((trifluoromethyl)sulfonyl)ethan-1-one: Another Utility for Electrophilic Trifluoromethylthiolation Reactions

(2016) Zhongyan Huang et al.   ChemistryOpen

New entries toward the synthesis of OCF3-containing molecules

(2016) Tatiana Besset et al.   Organic Chemistry Frontiers

Copper-catalyzed 8-amido chelation-induced regioselective C–H fluoroalkylation of quinolines

(2016) Li-Kun Jin et al.   Organic Chemistry Frontiers

Photochemical Perfluoroalkylation with Pyridine N -Oxides: Mechanistic Insights and Performance on a Kilogram Scale

(2016) Joel W. Beatty et al.   Chem

Copper-Catalyzed Trifluoromethylation of AliphaticN-Arylhydrazones: A Concise Synthetic Entry to 2-Trifluoromethylindoles from Simple Aldehydes

(2015) Alexis Prieto et al.   ADVANCED SYNTHESIS & CATALYSIS

Visible-Light Photoredox-Catalyzed C−H Difluoroalkylation of Hydrazones through an Aminyl Radical/Polar Mechanism

(2015) Pan Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Monofluorination of Organic Compounds: 10 Years of Innovation

(2015) Pier Alexandre Champagne et al.   CHEMICAL REVIEWS

Carbon Trifluoromethylation Reactions of Hydrocarbon Derivatives and Heteroarenes

(2015) Concepción Alonso et al.   CHEMICAL REVIEWS

Transition metal complex assisted Csp3–F bond formation

(2015) Xiaoxi Lin et al.   DALTON TRANSACTIONS

Regioselective Oxidative Trifluoromethylation of Imidazoheterocycles via C(sp2)–H Bond Functionalization

(2015) Kamarul Monir et al.   JOURNAL OF ORGANIC CHEMISTRY

A Fluorinated Ligand Enables Room-Temperature and Regioselective Pd-Catalyzed Fluorination of Aryl Triflates and Bromides

(2015) Aaron C. Sather et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Iridium-Catalyzed Enantioselective Fluorination of Racemic, Secondary Allylic Trichloroacetimidates

(2015) Qi Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of Chiral β-Fluoro α-Amino Acids via Pd(II)-Catalyzed Fluorination of Unactivated Methylene C(sp3)–H Bonds: Scope and Mechanistic Studies

(2015) Qi Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A mild and fast continuous-flow trifluoromethylation of coumarins with the CF3 radical derived from CF3SO2Na and TBHP

(2015) Xiaodan Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Palladium-Catalyzed Site-Selective Fluorination of Unactivated C(sp3)–H Bonds

(2015) Jinmin Miao et al.   ORGANIC LETTERS

Efficient Palladium-Catalyzed C–H Fluorination of C(sp3)–H Bonds: Synthesis of β-Fluorinated Carboxylic Acids

(2015) Qihua Zhu et al.   ORGANIC LETTERS

Direct trifluoromethylation of imidazoheterocycles in a recyclable medium at room temperature

(2015) Xiao-Ming Ji et al.   RSC Advances

Recent Advances in Research and Development of Fluorinated Drugs and New Methods for Fluorination, Mono-, Di-and Tri-fluoromethylation

(2015) Ji Zhang et al.   CHINESE JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed CF Bond FormationviaDirected CH Activation

(2014) Yan Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Mild and Versatile Nitrate-Promoted CH Bond Fluorination

(2014) Shao-Jie Lou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mild Copper-Catalyzed Fluorination of Alkyl Triflates with Potassium Fluoride

(2014) Hester Dang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct Catalytic Trifluoromethylthiolation of Boronic Acids and Alkynes Employing Electrophilic Shelf-StableN-(trifluoromethylthio)phthalimide

(2014) Roman Pluta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direct C–H trifluoromethylation of di- and trisubstituted alkenes by photoredox catalysis

(2014) Ren Tomita et al.   Beilstein Journal of Organic Chemistry

Copper-catalyzed olefinic C–H difluoroacetylation of enamides

(2014) Gilles Caillot et al.   CHEMICAL COMMUNICATIONS

Iron(iii)–salan complexes catalysed highly enantioselective fluorination and hydroxylation of β-keto esters and N-Boc oxindoles

(2014) Xin Gu et al.   CHEMICAL COMMUNICATIONS

Modern Carbon–Fluorine Bond Forming Reactions for Aryl Fluoride Synthesis

(2014) Michael G. Campbell et al.   CHEMICAL REVIEWS

Advances in Catalytic Enantioselective Fluorination, Mono-, Di-, and Trifluoromethylation, and Trifluoromethylthiolation Reactions

(2014) Xiaoyu Yang et al.   CHEMICAL REVIEWS

Beyond the Balz–Schiemann Reaction: The Utility of Tetrafluoroborates and Boron Trifluoride as Nucleophilic Fluoride Sources

(2014) Alexander J. Cresswell et al.   CHEMICAL REVIEWS

Good Partnership between Sulfur and Fluorine: Sulfur-Based Fluorination and Fluoroalkylation Reagents for Organic Synthesis

(2014) Chuanfa Ni et al.   CHEMICAL REVIEWS

Synthetic Methods for Compounds Having CF3–S Units on Carbon by Trifluoromethylation, Trifluoromethylthiolation, Triflylation, and Related Reactions

(2014) Xiu-Hua Xu et al.   CHEMICAL REVIEWS

Trifluoromethyltrimethylsilane: Nucleophilic Trifluoromethylation and Beyond

(2014) Xiao Liu et al.   CHEMICAL REVIEWS

Electrophilic Trifluoromethylation by Use of Hypervalent Iodine Reagents

(2014) Julie Charpentier et al.   CHEMICAL REVIEWS

Recent Progress in Direct Introduction of Fluorinated Groups on Alkenes and Alkynes by means of CH Bond Functionalization

(2014) Tatiana Besset et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Fluorination of 2-Oxind­oles by Structure-Micro-TunedN-Fluorobenzenesulfonamides

(2014) Fajie Wang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Direct Trifluoromethylthiolation Reactions: The “Renaissance” of an Old Concept

(2014) Fabien Toulgoat et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Recent advances in the trifluoromethylation methodology and new CF3-containing drugs

(2014) Wei Zhu et al.   JOURNAL OF FLUORINE CHEMISTRY

Palladium-Catalyzed ortho-Selective C–H Fluorination of Oxalyl Amide-Protected Benzylamines

(2014) Changpeng Chen et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd-Catalyzed Nucleophilic Fluorination of Aryl Bromides

(2014) Hong Geun Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Catalyzed Radical Fluorination of Alkylboronates in Aqueous Solution

(2014) Zhaodong Li et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Late Stage Benzylic C–H Fluorination with [18F]Fluoride for PET Imaging

(2014) Xiongyi Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-Light-Promoted Radical C–H Trifluoromethylation of Free Anilines

(2014) Jin Xie et al.   ORGANIC LETTERS

Copper-Catalyzed β-Trifluoromethylation of Conjugated Hydrazones

(2014) Alexis Prieto et al.   ORGANIC LETTERS

Copper-Catalyzed Synthesis of α-Trifluoromethylthio-Substituted Ketones

(2014) Yangjie Huang et al.   ORGANIC LETTERS

Catalytic C–H α-Trifluoromethylation of α,β-Unsaturated Carbonyl Compounds

(2014) Zhongxue Fang et al.   ORGANIC LETTERS

Late-stage [18F]fluorination: new solutions to old problems

(2014) Allen F. Brooks et al.   Chemical Science

Vanadium-catalyzed C(sp3)–H fluorination reactions

(2014) Ji-Bao Xia et al.   Organic Chemistry Frontiers

Direct Trifluoromethylation of the CH Bond

(2013) Hui Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

Formation of CSCF3Bonds through Direct Trifluoromethylthiolation

(2013) Anis Tlili et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Controlled Trifluoromethylation Reactions of Alkynes through Visible-Light Photoredox Catalysis

(2013) Naeem Iqbal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Manganese-Catalyzed Oxidative Benzylic C-H Fluorination by Fluoride Ions

(2013) Wei Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Trifluoromethylation ofN,N-Dialkylhydrazones

(2013) Etienne Pair et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Regioselective Fluorination of Allylic Halides

(2013) Zuxiao Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Directing-Group-Assisted Copper-Catalyzed Olefinic Trifluoromethylation of Electron-Deficient Alkenes

(2013) Chao Feng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed trifluoromethylation of alkenes with an electrophilic trifluoromethylating reagent

(2013) Xiao-Ping Wang et al.   Beilstein Journal of Organic Chemistry

Pd(OAc)2-catalyzed regioselective aromatic C–H bond fluorination

(2013) Shao-Jie Lou et al.   CHEMICAL COMMUNICATIONS

Copper-mediated C–H trifluoromethylation of quinones

(2013) Nadia O. Ilchenko et al.   CHEMICAL COMMUNICATIONS

CuCl-catalyzed ortho trifluoromethylation of arenes and heteroarenes with a pivalamido directing group

(2013) Shangjun Cai et al.   CHEMICAL COMMUNICATIONS

Visible-light-induced synthesis of a variety of trifluoromethylated alkenes from potassium vinyltrifluoroborates by photoredox catalysis

(2013) Yusuke Yasu et al.   CHEMICAL COMMUNICATIONS

Room temperature decarboxylative trifluoromethylation of α,β-unsaturated carboxylic acids by photoredox catalysis

(2013) Pan Xu et al.   CHEMICAL COMMUNICATIONS

Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)

(2013) Jiang Wang et al.   CHEMICAL REVIEWS

Copper-Boxmi Complexes as Highly Enantioselective Catalysts for Electrophilic Trifluoromethylthiolations

(2013) Qing-Hai Deng et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper-Mediated Trifluoromethylation of Terminal Alkynes byS-(Trifluoromethyl)diarylsulfonium Salt

(2013) Xiaoping Wang et al.   CHINESE JOURNAL OF CHEMISTRY

One-Pot, Two-Step, Microwave-Assisted Palladium-Catalyzed Conversion of Aryl Alcohols to Aryl Fluorides via Aryl Nonaflates

(2013) Johan Wannberg et al.   JOURNAL OF ORGANIC CHEMISTRY

Metal-Catalyzed Benzylic Fluorination as a Synthetic Equivalent to 1,4-Conjugate Addition of Fluoride

(2013) Steven Bloom et al.   JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Allylic C–H Fluorination

(2013) Marie-Gabrielle Braun et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium(III)-Catalyzed Fluorination of Arylboronic Acid Derivatives

(2013) Anthony R. Mazzotti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed, Directing Group-Assisted Fluorination of Arene and Heteroarene C–H Bonds

(2013) Thanh Truong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cu(OTf)2-Mediated Fluorination of Aryltrifluoroborates with Potassium Fluoride

(2013) Yingda Ye et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Trifluoromethanesulfonyl Hypervalent Iodonium Ylide for Copper-Catalyzed Trifluoromethylthiolation of Enamines, Indoles, and β-Keto Esters

(2013) Yu-Dong Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper Catalyzed β-Difluoroacetylation of Dihydropyrans and Glycals by Means of Direct C–H Functionalization

(2013) Marie-Charlotte Belhomme et al.   ORGANIC LETTERS

Trifluoromethylation of Allylsilanes under Photoredox Catalysis

(2013) Satoshi Mizuta et al.   ORGANIC LETTERS

An Improved Catalyst System for the Pd-Catalyzed Fluorination of (Hetero)Aryl Triflates

(2013) Hong Geun Lee et al.   ORGANIC LETTERS

Iron(II)-Catalyzed Benzylic Fluorination

(2013) Steven Bloom et al.   ORGANIC LETTERS

Copper-Catalyzed Direct C–H Trifluoromethylation of Quinones

(2013) Xi Wang et al.   ORGANIC LETTERS

Copper- and Iron-Catalyzed Decarboxylative Tri- and Difluoromethylation of α,β-Unsaturated Carboxylic Acids with CF3SO2Na and (CF2HSO2)2Zn via a Radical Process

(2013) Zejiang Li et al.   ORGANIC LETTERS

Cu-Catalyzed Fluorination of Diaryliodonium Salts with KF

(2013) Naoko Ichiishi et al.   ORGANIC LETTERS

Catalytic Decarboxylative Fluorination for the Synthesis of Tri- and Difluoromethyl Arenes

(2013) Satoshi Mizuta et al.   ORGANIC LETTERS

Pd(II)-Catalyzed Ortho-Trifluoromethylation of Benzylamines

(2013) Masanori Miura et al.   ORGANIC LETTERS

Efficient SN2 Fluorination of Primary and Secondary Alkyl Bromides by Copper(I) Fluoride Complexes

(2013) Yanpin Liu et al.   ORGANOMETALLICS

Copper(II)-Catalyzed Enantioselective Fluorination of β-Keto Esters Using Chiral Spiro Oxazoline Ligands

(2013) Kazutaka Shibatomi et al.   SYNLETT

Copper/Silver-Mediated Decarboxylative Trifluoromethylation of α,β-Unsaturated Carboxylic Acids with CF3SO2Na

(2013) Yaming Li et al.   SYNTHESIS-STUTTGART

Pd(PPh3)4-catalyzed direct ortho-fluorination of 2-arylbenzothiazoles with an electrophilic fluoride N-fluorobenzenesulfonimide (NFSI)

(2013) Qiuping Ding et al.   TETRAHEDRON

Enantioselective fluorination of α-chloro-β-keto phosphonates in the presence of chiral palladium complexes

(2013) Saet Byeol Woo et al.   TETRAHEDRON LETTERS

Enantioselective fluorination of β-ketoesters using tartrate derived bidentate bioxazoline-Cu(II) complexes

(2013) Kaluvu Balaraman et al.   TETRAHEDRON-ASYMMETRY

Copper-catalyzed fluorination of 2-pyridyl aryl bromides

(2013) Xin Mu et al.   Chemical Science

Efficient enantioselective fluorination of β-keto esters/amides catalysed by diphenylamine-linked bis(thiazoline)–Cu(OTf)2complexes

(2013) Jiahuan Peng et al.   RSC Advances

Copper-Catalyzed Trifluoromethylation of Allylsilanes

(2012) Ryo Shimizu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Polycomponent Metal-Catalyzed Aliphatic, Allylic, and Benzylic Fluorination

(2012) Steven Bloom et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Di- and Trifluoromethylation of α,β-Unsaturated Carboxylic Acids: A Protocol for Vinylic Fluoroalkylations

(2012) Zhengbiao He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Mono-Fluorination of α-Keto Esters: Synthesis of Optically Active β-Fluoro-α-Hydroxy and β-Fluoro-α-Amino Acid Derivatives

(2012) Shoko Suzuki et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Iron(II)-Catalyzed Trifluoromethylation of Potassium Vinyltrifluoroborates

(2012) Andrew T. Parsons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-catalyzed trifluoromethylation of aryl- and vinylboronic acids with generation of CF3-radicals

(2012) Yang Li et al.   CHEMICAL COMMUNICATIONS

Trifluoromethylation of Allylsilanes under Copper Catalysis

(2012) Satoshi Mizuta et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct CH Functionalization of Enamides and Enecarbamates by Using Visible-Light Photoredox Catalysis

(2012) Heng Jiang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Axially Chiral C2-Symmetric N-Heterocyclic Carbene (NHC) Palladium Complex-Catalyzed Asymmetric Fluorination and Amination of Oxindoles

(2012) Rui Zhang et al.   CHINESE JOURNAL OF CHEMISTRY

Palladium-Mediated Heck-Type Reactions of [(Bromodifluoromethyl)sulfonyl]benzene: Synthesis of α-Alkenyl- and α-Heteroaryl-Substituted α,α-Difluoromethyl Phenyl Sulfones

(2012) Nakin Surapanich et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

SPANphos Ligands in Palladium-Catalyzed Asymmetric Fluorination

(2012) Olivier Jacquet et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Copper-Catalyzed Oxidative Trifluoromethylation of Terminal Alkynes and Aryl Boronic Acids Using (Trifluoromethyl)trimethylsilane

(2012) Xueliang Jiang et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Enantioselective Fluorination of Unprotected 3-Substituted Oxindoles: One-Step Synthesis of BMS 204352 (MaxiPost)

(2012) Jun Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Trifluoromethylation of Alkenes by Visible Light Photoredox Catalysis

(2012) Naeem Iqbal et al.   JOURNAL OF ORGANIC CHEMISTRY

Pd(II)-Catalyzed Ortho Trifluoromethylation of Arenes and Insights into the Coordination Mode of Acidic Amide Directing Groups

(2012) Xing-Guo Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Catalyzed Decarboxylative Fluorination of Aliphatic Carboxylic Acids in Aqueous Solution

(2012) Feng Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Enantioselective Copper-Catalyzed Electrophilic Trifluoromethylation of β-Ketoesters

(2012) Qing-Hai Deng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Trifluoromethylation of Aromatic C–H Bond Directed by an Acetamino Group

(2012) Li-Sheng Zhang et al.   ORGANIC LETTERS

Palladium-Catalyzed Allylic Fluorination of Cinnamyl Phosphorothioate Esters

(2012) Andrew M. Lauer et al.   ORGANIC LETTERS

Pd-Catalyzed C–H Fluorination with Nucleophilic Fluoride

(2012) Kate B. McMurtrey et al.   ORGANIC LETTERS

Oxidative Aliphatic C-H Fluorination with Fluoride Ion Catalyzed by a Manganese Porphyrin

(2012) W. Liu et al.   SCIENCE

Mild copper-catalyzed trifluoromethylation of terminal alkynes using an electrophilic trifluoromethylating reagent

(2012) Zhiqiang Weng et al.   TETRAHEDRON

Copper-catalyzed trifluoromethylation of terminal alkynes using Umemoto’s reagent

(2012) Dong-Fen Luo et al.   TETRAHEDRON LETTERS

Synthesis of trifluoromethylated acetylenes via copper-catalyzed trifluoromethylation of alkynyltrifluoroborates

(2012) Huidong Zheng et al.   TETRAHEDRON LETTERS

Oxytrifluoromethylation of multiple bonds using copper catalyst under mild conditions

(2012) Hiromichi Egami et al.   TETRAHEDRON LETTERS

Copper-catalyzed olefinic trifluoromethylation of enamides at room temperature

(2012) Chao Feng et al.   Chemical Science

Regio- and stereoretentive synthesis of branched, linear (E)- and (Z)-allyl fluorides from allyl carbonates under Ir-catalysis

(2012) Elena Benedetto et al.   Chemical Science

Rhenium-Catalyzed Trifluoromethylation of Arenes and Heteroarenes by Hypervalent Iodine Reagents

(2012) Esteban Mejía et al.   ACS Catalysis

Palladium-Catalyzed Allylic Fluorination

(2011) Charlotte Hollingworth et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed Selective Monofluorination of Benzoic Acids Using a Practical Auxiliary: A Weak-Coordination Approach

(2011) Kelvin S. L. Chan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper-Catalyzed Trifluoromethylation of Unactivated Olefins

(2011) Andrew T. Parsons et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Oxidative Trifluoromethylation of Indoles at Room Temperature

(2011) Xin Mu et al.   CHEMISTRY-A EUROPEAN JOURNAL

The Synthesis of a New Class of Chiral Pincer Ligands and Their Applications in Enantioselective Catalytic Fluorinations and the Nozaki-Hiyama-Kishi Reaction

(2011) Qing-Hai Deng et al.   CHEMISTRY-A EUROPEAN JOURNAL

An Improved Copper-Mediated Oxidative Trifluoromethylation of Terminal Alkynes

(2011) Ke Zhang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Iridium-Catalyzed Allylic Fluorination of Trichloroacetimidates

(2011) Joseph J. Topczewski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Regio- and Enantioselective Fluorination of Acyclic Allylic Halides

(2011) Matthew H. Katcher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Copper-Catalyzed C(sp3)–C(sp3) Bond Formation Using a Hypervalent Iodine Reagent: An Efficient Allylic Trifluoromethylation

(2011) Xi Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Mediated Trifluoromethoxylation of Aryl Stannanes and Arylboronic Acids

(2011) Chenghong Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalysis for fluorination and trifluoromethylation

(2011) Takeru Furuya et al.   NATURE

Trifluoromethylation of arenes and heteroarenes by means of photoredox catalysis

(2011) David A. Nagib et al.   NATURE

Enantioselectivegem-Chlorofluorination of Active Methylene Compounds Using a Chiral Spiro Oxazoline Ligand

(2011) Kazutaka Shibatomi et al.   ORGANIC LETTERS

Copper-Catalyzed Trifluoromethylation of Aryl and Vinyl Boronic Acids with An Electrophilic Trifluoromethylating Reagent

(2011) Tianfei Liu et al.   ORGANIC LETTERS

The Palladium-Catalyzed Trifluoromethylation of Vinyl Sulfonates

(2011) Eun Jin Cho et al.   ORGANIC LETTERS

SPANamine derivatives in the catalytic asymmetric α-fluorination of β-keto esters

(2011) Olivier Jacquet et al.   TETRAHEDRON-ASYMMETRY

Catalytic Enantioselective Fluorination of α-Chloro-β-keto Esters in the Presence of Chiral Nickel Complexes

(2010) Seung Hee Kang et al.   ADVANCED SYNTHESIS & CATALYSIS

Aromatic and heterocyclic perfluoroalkyl sulfides. Methods of preparation

(2010) Vladimir N Boiko   Beilstein Journal of Organic Chemistry

Enantioselective α-Fluorination and Chlorination of β-Ketoesters by Cobalt Catalyst

(2010) Motoi Kawatsura et al.   CHEMISTRY LETTERS

Functionalization of Organic Molecules by Transition-Metal-Catalyzed C(sp3)H Activation

(2010) Rodolphe Jazzar et al.   CHEMISTRY-A EUROPEAN JOURNAL

Copper-Mediated Aerobic Oxidative Trifluoromethylation of Terminal Alkynes with Me3SiCF3

(2010) Lingling Chu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Palladium-Catalyzed Asymmetric Synthesis of Allylic Fluorides

(2010) Matthew H. Katcher et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pd(II)-Catalyzedortho-Trifluoromethylation of Arenes Using TFA as a Promoter

(2010) Xisheng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Catalyzed Late-Stage Fluorination

(2010) Pingping Tang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Palladium-Catalyzed Trifluoromethylation of Aryl Chlorides

(2010) E. J. Cho et al.   SCIENCE

Molecular Imaging with PET

(2008) Simon M. Ametamey et al.   CHEMICAL REVIEWS

Dehydrofluorination of Hydrofluorocarbons by Titanium Alkylidynes via Sequential C−H/C−F Bond Activation Reactions. A Synthetic, Structural, and Mechanistic Study of 1,2-CH Bond Addition and β-Fluoride Elimination

(2008) Alison R. Fout et al.   ORGANOMETALLICS

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS

Versatile application of trifluoromethyl triflate

(2007) Alexander A. Kolomeitsev et al.   TETRAHEDRON LETTERS