Connexin 43 dephosphorylation contributes to arrhythmias and cardiomyocyte apoptosis in ischemia/reperfusion hearts

Regulation of the phosphoprotein phosphatase 2A system and its modulation during oxidative stress: A potential therapeutic target?

(2019) I.S. Elgenaidi et al.   PHARMACOLOGY & THERAPEUTICS

Connexin43 dephosphorylation at serine 282 is associated with connexin43-mediated cardiomyocyte apoptosis

(2019) Yutong Yang et al.   CELL DEATH AND DIFFERENTIATION

Things get broken: the hypoxia-inducible factor prolyl hydroxylases in ischemic heart disease

(2019) Timm Schreiber et al.   BASIC RESEARCH IN CARDIOLOGY

Connexin 43-serine 282 modulates serine 279 phosphorylation in cardiomyocytes

(2019) Zhipeng Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Spatio-temporal regulation of connexin43 phosphorylation and gap junction dynamics

(2018) Joell L. Solan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Regulation of cardiac gap junctions by protein phosphatases

(2017) Ashleigh R. Hood et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Increased Cardiac Arrhythmogenesis Associated With Gap Junction Remodeling With Upregulation of RNA-Binding Protein FXR1

(2017) Miensheng Chu et al.   CIRCULATION

Sphingosine-1-phosphate reduces ischaemia–reperfusion injury by phosphorylating the gap junction protein Connexin43

(2016) Sandrine Morel et al.   CARDIOVASCULAR RESEARCH

Connexin 43 is an emerging therapeutic target in ischemia/reperfusion injury, cardioprotection and neuroprotection

(2015) Rainer Schulz et al.   PHARMACOLOGY & THERAPEUTICS

p38 MAPK in cardioprotection - are we there yet?

(2014) E D Martin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cx43 phosphorylation on S279/282 and intercellular communication are regulated by IP3/IP3 receptor signaling

(2014) Man Kang et al.   Cell Communication and Signaling

Genetic deletion of the adaptor protein p66Shc increases susceptibility to short-term ischaemic myocardial injury via intracellular salvage pathways

(2014) Alexander Akhmedov et al.   EUROPEAN HEART JOURNAL

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

(2014) Edward T. Chouchani et al.   NATURE

Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels

(2013) Indra Lübkemeier et al.   BASIC RESEARCH IN CARDIOLOGY

Extracellular matrix protein CCN1 regulates cardiomyocyte apoptosis in mice with stress-induced cardiac injury

(2013) P.-L. Hsu et al.   CARDIOVASCULAR RESEARCH

Injury-triggered Akt phosphorylation of Cx43: a ZO-1-driven molecular switch that regulates gap junction size

(2013) C. A. Dunn et al.   JOURNAL OF CELL SCIENCE

Mechanism and consequence of the autoactivation of p38α mitogen-activated protein kinase promoted by TAB1

(2013) Gian Felice De Nicola et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The antiarrhythmic dipeptide ZP1609 (danegaptide) when given at reperfusion reduces myocardial infarct size in pigs

(2013) Andreas Skyschally et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Cardiomyocyte-specific deletion of survivin causes global cardiac conduction defects

(2012) Jan Wilko Schrickel et al.   BASIC RESEARCH IN CARDIOLOGY

Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury

(2012) Nan Wang et al.   BASIC RESEARCH IN CARDIOLOGY

Conduction Remodeling in Human End-Stage Nonischemic Left Ventricular Cardiomyopathy

(2012) Alexey V. Glukhov et al.   CIRCULATION

A new method of ultrasonic nonviral gene delivery to the adult myocardium

(2012) Youakim Saliba et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Connexin43 phosphorylation and cytoprotection in the heart

(2011) Maya M. Jeyaraman et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Phosphatase-Resistant Gap Junctions Inhibit Pathological Remodeling and Prevent Arrhythmias

(2011) Benjamin F. Remo et al.   CIRCULATION RESEARCH

A Peptide Mimetic of the Connexin43 Carboxyl Terminus Reduces Gap Junction Remodeling and Induced Arrhythmia Following Ventricular Injury

(2011) Michael P. O'Quinn et al.   CIRCULATION RESEARCH

Mitochondrial connexin 43 impacts on respiratory complex I activity and mitochondrial oxygen consumption

(2011) Kerstin Boengler et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Ischemia and reperfusion—from mechanism to translation

(2011) Holger K Eltzschig et al.   NATURE MEDICINE

Connexin Modulators and Their Potential Targets under the Magnifying Glass

(2010) S. B. Bodendiek et al.   CURRENT MEDICINAL CHEMISTRY

Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium

(2010) James W. Smyth et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitogen-Activated Protein Kinase Signaling in the Heart: Angels Versus Demons in a Heart-Breaking Tale

(2010) Beth A. Rose et al.   PHYSIOLOGICAL REVIEWS

Connexin43 phosphorylation: structural changes and biological effects

(2009) Joell L. Solan et al.   BIOCHEMICAL JOURNAL

Connexin43 in cardiomyocyte mitochondria contributes to mitochondrial potassium uptake

(2009) Elisabet Miro-Casas et al.   CARDIOVASCULAR RESEARCH

Phosphorylation of connexin-43 at serine 262 promotes a cardiac injury-resistant state

(2009) Wattamon Srisakuldee et al.   CARDIOVASCULAR RESEARCH

Connexin-related signaling in cell death: to live or let die?

(2009) E Decrock et al.   CELL DEATH AND DIFFERENTIATION

Ion Channel Subunit Expression Changes in Cardiac Purkinje Fibers

(2009) Ange Maguy et al.   CIRCULATION RESEARCH

Electrophysiological Consequences of Acute Regional Ischemia/Reperfusion in Neonatal Rat Ventricular Myocyte Monolayers

(2008) Carlos de Diego et al.   CIRCULATION

Nuclear Ca2+ sparks and waves mediated by inositol 1,4,5-trisphosphate receptors in neonatal rat cardiomyocytes

(2007) Dali Luo et al.   CELL CALCIUM